📍Hydroxyzine is a first-generation H1 antagonist

📌Sedative action is pronounced

#pharmacology #MedStudentTwitter #MedTwitter
📍Cetirizine is a second generation H1 antagonist

📌An active metabolite of hydroxyzine

📌Less sedative action when compared to hydroxyzine but has higher sedative action than most of the other second generation H1 antagonists
📍Levocetirizine is the active enantiomer of cetirizine

📌More potent than cetirizine and can be used at half the dose of cetirizine with lesser sedation

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