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Nov 3 19 tweets 4 min read
Seizure semiology and localization: not everything is generalized onset tonic-clonic. 🧠⛈️

Part 2: motor symptoms

🤔

#Neurology #neurotwitter #Teaching #Education #EndNeurophobia

1/🧵
Intro
The following symptoms are frequently seen in focal and focal to bilateral tonic-clonic seizures.

2/🧵 Image
🚨
This tweetorial is based on:
Epilepsy Behav. 2005 Aug;7(1):1-17.
doi: 10.1016/j.yebeh.2005.04.004
This paper was written using the previous classification system and some data may need an update, nevertheless I find it useful when teaching about seizure semiology. 📓

3/🧵 Image
Motor symptoms:
1⃣

Sx: Forced Head Turn and Eye Deviation.

Where? Frontal eye and motor areas anterior to the precentral gyrus (Brodmann areas 6 and 8). Contralateral to the head turn.

4/🧵 Image
Examples are found even in art!

The Transfiguration by Raphael de Sanzio.

5/🧵 Image
Motor symptoms:
2⃣

Sx: Late version at the end of a bilateral seizure.

Where? Ipsilateral Brodmann area 6.

6/🧵
Motor symptoms:
3⃣

Sx: Unilateral clonic activity.

Where? Contralateral primary motor area (Brodmann area 4).

7/🧵 Image
Motor symptoms:
4⃣

Sx: Last clonic jerk.

Where? Ipsilateral to the seizure onset.

8/🧵
Motor symptoms:
5⃣

Sx: Unilateral tonic activity.

Where? Contralateral frontal lobe.

9/ 🧵
Motor symptoms:
6⃣

Sx: Asymmetric tonic limb posturing ("figure-of-4 sign" and "Fencing Posture").

Where? Hemisphere (frontal supplemental motor area more than temporal) contralateral to the extended limb.

10/🧵 ImageImage
Motor symptoms:
7⃣

Sx: Unilateral dystonic posturing.

Where? Contralateral to the side of seizure onset.

11/🧵
Motor symptoms:
8⃣

Sx: Automatisms with preserved responsiveness.

Where? Nondominant temporal lobe.

12/🧵
Motor symptoms:
9⃣

Sx: Ictal spitting.

Where? Nondominant temporal lobe.

13/🧵
Motor symptoms:
🔟

Sx: Ictal vomiting.

Where? Lateral superior and inferior structures of the nondominant temporal lobe.

14/🧵
Motor symptoms:
1⃣1⃣

Sx: Unilateral ictal eye blinking.

Where? Ipsilateral to the ictal discharge.

15/🧵
Motor symptoms:
1⃣2⃣

Sx: Ictal paresis.

Where? Contralateral hemisphere.

16/🧵
This was the second part of the Seizure semiology tweetorial, wait for parts 3 (language features) and 4 (postictal features) in the next couple of days.

Below are the sources.

Hope you liked it! 🤓

17/17
Sources:
1.- Epilepsy Behav. 2005 Aug;7(1):1-17.
doi: 10.1016/j.yebeh.2005.04.004
2.- Epilepsia. 2017 Apr;58(4):522-530.
doi: 10.1111/epi.13670
3.- Blumenfield's Neuroanatomy Through Clinical Cases. 2nd Edition, 2010.
Sources:
4.- Mayo Clinic Board Review. Clinical neurology for initial certification and MOC. 2015.
5.- Epilepsy Behav. 2010 Feb;17(2):139-46.
doi: 10.1016/j.yebeh.2009.10.006

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More from @MedinaRiojaMD

Nov 2
In November 29, the World Movement Disorders day is celebrated.

#MoveDisorder #Neuro #Teaching #EndNeurophobia

1/🧵 Image
That is a great reason for a small tweetorial on how to approach phenomenology, the key element of this branch in Neurology. 🧠

2/🧵
But first, what is phenomenology?
That is a term that refers to the description of the movement. Instead of trying inmmediately to put a label on what you see, first I suggest start by watching and describing. 🤔

#Noticing

3/🧵 Image
Read 15 tweets
Oct 31
Seizure semiology and localization: not everything is generalized onset tonic-clonic. 🧠⛈️

Part 1: non motor symptoms

🤔

#Neurology #neurotwitter #Teaching #Education #EndNeurophobia

1/🧵
Intro
As the 2017 ILAE Classification of Seizure types states, there are many signs and symptoms that can have an epileptic origin. Some of them are motor and others are non motor.

2/🧵
Intro
The non motor symptoms are more frequently seen in focal epilepsies.

3/🧵
Read 18 tweets
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Today's reflection: brain health. 🧠🏥

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1/🧵
It is the only organ that cannot be transplanted and that can be changed literally by talking to it. It can perform 1 billion billion calculations per second and unlike artificial intelligence, can imagine, create, and anticipate.
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2/🧵
It is the most precious 3 pounds in the known
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🤔
3/3
Read 4 tweets
Oct 26
REM Sleep Behavior Disorder (RBD): what Miguel de Cervantes and Cinderella taught us. 😴😴💤🧠🧠👸✍️

A brief tweetorial.

#Neuro #NeuroTwitter #EndNeurophobia #Teaching #NeuroEducation #Sleep #RBD

1/🧵
The following thread has the objective to describe (in a general way) the main features of RBD, for more details, feel free to check the sources that I will add at the end of the tweetorial.

2/🧵
🥇What is REM sleep?
Sleep is divided in 4 phases, each of them is repeated during the 🌕in a cycle.

N1: vertex waves
N2: sleep spindles, k complexes
N3: slow-wave-sleep (restorative phase)
REM: rapid horizontal eye movement occurs, we dream and there is no muscle tone

3/🧵
Read 22 tweets
Oct 25
Clinical pearl of the week ⚪️

Lower limb 🦵paraparesis + Babinski + Lack of marked spasticity + absent ankle reflexes = think myeloneuropathy syndrome.

1/
And...
Lower limb 🦵paraparesis + Babinski + Marked spasticity = think spastic paraparesis syndrome.

2/
Remember:
🤔
Clinical syndrome: signs and symptoms with a common pathophysiological mechanism but with different ETIOLOGIES (metabolic, infectious, genetic, etc.)

3/
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1/🧵
Definition:
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🧑‍🏫
2/🧵
Many clinical SYNDROMES share Frontotemporal Lobar Degeneration Pathology (FTLD) and are grouped in this spectrum of disorders. 🔬

3/🧵
Read 20 tweets

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