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Ernesto LopezAlmaraz Profile picture
@kidney_doctor
Nov 6, 2022 • 10 tweets • 15 min read • Read on X
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Drug Induced Acute Interatitital Nephritis #AIN #AKI #KidneyWk @ASNKidney
In it’s pathogenesis allergic reaction mechanisms are involved #AIN #AKI #KidneyWk @ASNKidney
The p-i concept in #AIN indiuced #AKI #KidneyWk @ASNKidney also consider genetic susceptibility
… on clinical presentation it may have different characteristics that may mimic other conditions… #AIN #AKI #KidneyWk @ASNKidney
… some tools can be used for the diagnosis #AIN #AKI #KidneyWk @ASNKidney
Talking about Treatment! Steroid use has different evidence #AIN #AKI #KidneyWk @ASNKidney
What about prognosis?

#AIN #AKI #KidneyWk @ASNKidney
A word on Checkpoint Inhibitors (1/2) #AIN #AKI #KidneyWk @ASNKidney
Checkpoint inhibitors (2/2) #AIN #AKI #KidneyWk @ASNKidney
Unmet needs in #AIN #AKI #KidneyWk @ASNKidney

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More from @kidney_doctor

Ernesto LopezAlmaraz Profile picture
Nov 6, 2022
Different mechanisms related to Cyrstal Induced Kidney Damage
#CystalDamage #AKI #KidneyWk @ASNKidney
Sulfadiazine, Acyclovir, Methothrexate, Ataxanavir clinical vignettes of #CystalDamage #AKI #KidneyWk @ASNKidney
Summary of some medications causing crystalline nephropathies. #CystalDamage #AKI #KidneyWk @ASNKidney
Read 6 tweets
Ernesto LopezAlmaraz Profile picture
Nov 6, 2022
#DrugToxicity a focus on mithocondrial damage. Consider different factors related to drug toxicity.
#KidneyWk @ASNKidney
Proximal Convoluted Tubule involved in toxicity due to hi density of mitochondria #DrugToxicity #KidneyWk @ASNKidney
Clinical presentations of #DrugToxicity #KidneyWk @ASNKidney
Read 6 tweets
Ernesto LopezAlmaraz Profile picture
Nov 6, 2022
Plenary #3 at @ASNKidney #KidneyWk on Wearable Devices for Fluid Management: nanomaterials for #KidneyHealth - Silicon integrated circuits
Devices mounted in the human body at different sites to monitor health status: different capabilities, minimally invasive (i.e. neonatal)
#WearableDevices #KidneyWk @ASNKidney
Some approved by FDA, other already deployed outside the US
#WearableDevices #KidneyWk @ASNKidney
Read 11 tweets
Ernesto LopezAlmaraz Profile picture
Nov 5, 2022
Mechanical Circulatory Support Devices and the Kidney beyond Cardiogenic Shock (high incidence of AKI) #CirculatoryDevices
#KidneyWk @ASNKidney ImageImageImageImage
Intravascular Devices: IAMP and Impella and their relationship with GFR and/or AKI
#CirculatoryDevices
#KidneyWk @ASNKidney ImageImageImageImage
Impact of these intravascular devices on Kidney Function and AKI
#CirculatoryDevices
#KidneyWk @ASNKidney ImageImage
Read 9 tweets
Ernesto LopezAlmaraz Profile picture
Nov 5, 2022
Focus on POCUS in CRS #FluidManagement
First of all understand what is POCUS and how to use it
#KidneyWk @ASNKidney
Focused Clinical Questions in #AKI. Which are our regular tools and how they perform? @NephroP
#POCUS #KidneyWk @ASNKidney
Physical Exam in Real Life, Fluid Balance (I&O’s) in real life vs. FoCUS
#POCUS #KidneyWk @ASNKidney
Read 8 tweets
Ernesto LopezAlmaraz Profile picture
Nov 5, 2022
A MUST: “mRNA as a medicine” Melissa Moore, MD leads us through drug development, from Penicillin to MABs #KidneyWk @ASNKidney
More than 100 monoclonal antibodies have been approved by @US_FDA but they have multiple limitations #KidneyWk @ASNKidney
Proteins have been used as medicine, but only a small proportion can be used, whereas mRNA enable the body to produce “own medicine” #KidneyWk @ASNKidney
Read 9 tweets

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