1/ Highlighting the strawman &loose associations bw diet &othr beliefs is a standard tactic 2 get clicks and rile the base
But you'd think this fellow would have insight not to TW this fluff directly after we published an editorial refuting his claims sciencedirect.com/science/articl…
2/ I don't have an issue if one wants to make a counterpoint to a direct claim
But all he's doing by pulling out the broad brush and capitalizing on stereotypes is exacerbating pre-existing polarizations and thus undermining efforts to engage in productive & educational dialogue
3/ Also pitiful when a medical "professional" feels the need to make himself a joke and brand-build by consistently targeting a dietary pattern
Might the evidently many hours spent teasing others be better spent on trying to write something productive?
2/ in the largest prospective trial to date (WHS, median follow-up was 21.4 years. N=28 024 women aged >45 years). LP-IR had an adjusted hazards ratio of 6.4 for coronary disease, as compared to 4.3 for obesity 3.9 for smoking and only 1.3 for LDL-C.
3/ in other words, there was ~ 540% increase in coronary disease risk with insulin resistance but only ~30-40% for LDL-C. Furthermore, there was likely an interaction between terms as the association didn’t hold for large LDL but was driven by small LDL, which is associated w/ IR
1/ Have you seen the New Non-Nutritive sweeteners paper in Cell making the rounds!?! Fantastic!
Here's a video rundown:
And this thread contains a brief tweetorial...
2/ This study took 120 young health people who didn't consume non-nutritive sweeteners (NNS) and broke them into 6 groups, n = 20/group
👉 Control (no supplement)
👉 Glucose
👉 Sacchrin
👉 Sucralose
👉 Aspartame
👉 Stevia
7 day baseline, 14 day exposure, and 7 day follow-up
3/ There was a clear individualized response across NNS, with Sucralose and Saccharin having the largest impact on glucose tolerance on oral glucose tolerance test.
There were "responders" (who had worse glucose tolerance in response to NNS) and also non-responders.
2/ The story behind this study started back in the fall, when a grass-roots group of my peers expressed interest in designing a "Metabolic Health Immersion" program to help us learn about how lifestyle impacts metabolism and health...
3/ 40 students wore CGM for 10-40 days, and a subgroup also engaged in journal clubs, patient panels, dietary tracking, and took intake and completion questionnaires with qualitative and quantitative components 👇