Discover and read the best of Twitter Threads about #ketogenic

Most recents (24)

Starting a ketogenic diet? Ease into it. It's more comfortable and practical for most people to go slow, especially if you're on certain meds that affect blood pressure or blood sugar. 🧵(1/5)
Some of you are going to want to go fast and restrict carbs low right away. That's just more of your style. Just know that sustaining this big behavioral change can be easier to maintain when you give yourself a few weeks to get used to what you are doing. (2/5)
Regardless, it's important to set yourself up for success by working with someone who knows you and can help you figure out the best approach for your lifestyle, personality, and likes and dislikes when implementing a #ketogenic diet for #mentalillness. (3/5)
Read 5 tweets
Can eating a ketogenic diet improve symptoms of serious mental illness? Yes. Yes it can. And once again, I am not just making this up. 🧵(1/5)
A study was done at Clinique du Castelviel (Psychiatric Hospital) in Castelmarou, France, with 28 participants (12 #bipolar, 6 major #depression, and 10 #schizophrenia). (2/5)
They were put on classic keto macros. Do you want to know what happened in this severely mentally ill, hospitalized population? (3/5)
Read 5 tweets
What are the brain changes we see with a #ketogenic diet? This thread will refer to a published paper on #bipolar, but I want you to understand that any mental illness or neurological disorder will benefit from these changes. 1/13
First, let's begin by discussing changes in energy. Ketone bodies are a primary energy source for the brain leading to more efficient ATP (energy) production. They increase vascular density, which means more nutrition and oxygen for the brain. 2/13
Increased ketone bodies increase brain metabolism. You would think being able to burn more energy in a bipolar brain is a bad idea, but when there is an energy problem in the brain, neuronal structures become stressed and hyperexcitable. 3/13
Read 13 tweets
Twitter Thread Alert! 🧵It's time for a mini-review of the literature on the use of #ketogenic diets and #Autism. Now some of you identify as neurodivergent and are not interested in modifying these differences. #neurotwitter 1/29
You may also not want to participate in a discussion that sees these differences as pathology. If that is the case, this is not the thread for you. I am not interested in hosting that philosophical discussion in this thread. 2/29 #boundaries
This thread is for people who are experiencing distress around what they experience as symptoms, and they deserve to know all the ways they can feel better. And I am going to tell them. So with that caveat, let's begin.👇3/29
Read 29 tweets
In my clinical experience as a mental health counselor working with clients with bipolar disorder, I have seen a reduction in ##medication usage and stability in #mood 1/8
One of the most exciting parts of this work is seeing my clients imagine themselves as someone who is well. #Bipolar disorder can supersede someone's sense of self, making them believe their symptoms are their personality. 2/8
However, I see the opening of possibilities and improvement in function as they start to dream about doing other things. Some of my clients choose to stay on some medications, but usually, there is a lowering of the dosages and discontinuation of many. 3/8
Read 8 tweets
Thread Alert 🧵: Let's talk about Parkinson's Disease 1/25 #Parkinsons #neurotwitter
In 2005 there was this study that, although very small, showed benefits. "Unified Parkinson’s Disease Rating Scale scores improved in all five during hyperketonemia" 2/25…
It wasn't designed to rule out a placebo effect. But the result should have resulted in excitement and further studies being done. 3/25
Read 25 tweets
Would you like to know about a randomized crossover trial that used a modified #ketogenic diet in #Alzheimers disease? 1/9
26 patients with clinically confirmed #Alzheimers disease were randomly assigned to a modified ketogenic diet or a usual diet supplemented with low-fat “healthy” eating guidelines and enrolled them 2/9
in a single-phase, assessor-blinded, two-period crossover trial. That means (2) 12-week treatment periods, separated by a 10-week washout period. 3/9
Read 9 tweets
According to a 2018 Cochrane Review, most individuals affected with #epilepsy can eliminate seizures with medication, but about 30% cannot. 1/4
About 1/3 to ½ of people with drug-resistant #epilepsy can reduce seizure frequency by at least 50% with a #ketogenic diet 2/4…
Are people offered a ketogenic diet from the onset of diagnosis as an alternative to medication? Do they have the right to be offered a ketogenic intervention alongside medications as an option? 3/4
Read 4 tweets
Thread alert! Advice from @bschermd at @Metabolic_Mind about the #ketogenic diet as a treatment for #mentalillness 🧵⬇️ #depression #ADHD #Bipolar #Schizophrenia #OCD #Anxiety #PTSD (1/8)
@bschermd @Metabolic_Mind "Remember our caution. Therapeutic
nutritional #ketosis or simply starting
a ketogenic diet is a powerful #health
and medical intervention that can change
your body's #metabolism and could
dramatically alter (2/8)
@bschermd @Metabolic_Mind #brain function, medications, #sleep patterns, #energy levels, and other physiologic functions. You should not start a keto diet on your own. (3/8)
Read 8 tweets
The Unique Regulation of Glucose and Ketosis in the Brain 🧵(1/4)
Regulatory controls are tighter in the brain than in the periphery. Glucose and glycogen regulation happens in the glia in the brain. #glia (2/4)
Ketosis can take 24-36 hours to achieve in the periphery, but the brain goes into ketosis every night. Glial glycogen stores are depleted within 6-8 hours. #ketones (3/4)
Read 4 tweets
A well-formulated ketogenic diet for brain health excludes grains. Let me tell you why. (1/7) #ketogenic
The effect of glutens aside, you want the full benefit of your nutrient-rich diet. You don't want to eat things that bind to the minerals you eat and make them inaccessible for your use. Like, you can do that, but what's the point? (2/7) #nutrition
Your brain needs minerals for optimal functioning. It's all about the mitochondria. And they need those minerals. Check out these key points from this important paper 👇(3/7)…
Read 7 tweets
People with Generalized Anxiety Disorder are seen to suffer from hypometabolism in the basal ganglia and white matter. This is thought to contribute to their struggle to determine what concern deserves attention & worry constantly.
Could improvement in brain metabolism help reduce some of the symptoms seen in #GAD? In my clinical experience, I would say absolutely.
I help clients transition to a ketogenic diet to help treat brain hypometabolism. And in doing so I see an improvement in #GAD symptoms and a variety of other symptoms associated with other diagnoses.
Read 4 tweets
The less we eat, the longer we live

1. This seems to be true.
A recent extensive review of studies done in geographies with maximum 100+ aged people showed that most of them practiced some form of calories restriction (CR) right from childhood.
#fasting #Longevity #MedTwitter
2. Calorie restriction (CR) is defined as consuming fewer (10-30% lower) calories as compared to usual.
This can be achieved by either intermittent fasting, or time-restricted feeding or substantially reducing carbohydrate intake.
#nutrition #HealthyEating
3. In ageing, #Insulin increases and insulin sensitivity decreases, which increase the risk of #diabetes, #obesity and #cardiovascular diseases. CR reverses these- reduces insulin levels and increases insulin sensitivity. #Glucose levels also reduce with CR.
Read 10 tweets
🚨 NEW! Lean Mass Hyper-Responder Editorial🚨

👉 10 MD & PhD authors from 4 countries🌍coming together for 1st of it's kind Consensus Statement on #LMHR

👉 Published in official Journal of the National Lipid Association @LipidJournal

A thread 🧵👇… Image
2/ A bit of background to catch some of you up

Over the past 6 years a population of people has emerged who demonstrate ⬆️ LDL on a #ketogenic diet in the context of ⬇️TG +⬆️HDL

Phenotype was first observed by @realDaveFeldman and (historically) named Lean Mass Hyper-Responders Image
3/ 1 year ago, we started researching #LMHR more formally, and in this year, we've published 4 prior papers

Cohort Study
Case Report
Cholesterol drop protocol
Lipid Energy Model
Read 11 tweets
Restricting total carbs has a much bigger effect than just restricting sugars in the first 24 hours

Check out our latest study (led by @AaronHengist) on carb and sugar restriction 🧵 (1/11)…

#lchf #lowcarb #carbs #highfat #keto #ketogenic #diet #health
The main aim was to see if restricting sugars or total carbs alters physical activity levels

This is because previous studies suggested fasting can lower physical activity & this can happen quickly

We wanted to know if this was due to carbs or energy

What did we find?
25 people (15 female) ate 3 diets for 24 hours with a variety of metabolic and energy balance measures
Read 11 tweets
Sometimes something so cool comes out I can't wait until a Live Brain Fog Recovery Program Lesson to share some of the scientific reasons for doing the program! So here it goes... 🧵
In a recent study on the diet-microbiome-gut-brain nexus in acute and chronic brain injury, findings have shown that the microbiome is affected by neurodegenerative conditions and brain injury states.
While the specific changes to the microbiomes of people suffering from different neurological disorders vary, there is a theme seen in both acute and chronic brain injury. And that theme is that pathogenic and opportunistic bacteria increase and beneficial flora becomes depleted.
Read 5 tweets
Let's review quickly all of the science I've come across in the past week that applies to high-fat ketogenic carnivore type diets.

I'll post the link, an image of the abstract, the title, and some hashtags on each one.

1/n - My public Zotero Database:…
Red and processed meat intakes and cardiovascular disease and type 2 diabetes mellitus: An umbrella systematic review and assessment of causal relations using Bradford Hill’s criteria

"do not support causality"

#T2D #CVD #SystematicReview #RedMeat…
Do #Vegetarian Diets Provide Adequate Nutrient Intake during Complementary Feeding? A Systematic Review

Complementary Feeding is the period when you're weaning a child onto non-breastmilk foods.

TLDR: "Not safe, critical micronutrient deficiency risk"…
Read 23 tweets
1) Welcome to a new #accredited (0.75h CE/#CME) #tweetorial on challenging case presentations for pts with #cardiometabolic disease, #CaReMe #FOAMed.
Our expert author is Claire Davies. @claireyrivs is a specialist diabetes & endocrinology #pharmacist working in Gateshead in 🇬🇧. Image
2) She is a member of UKCPA Diabetes & Endocrinology committee @UKCPADiabetes & works across #diabetes, #endocrinology, & emergency/acute care in Secondary Care. She is currently involved in development of regional guidelines & education to support medicines optimisation for PLWD
3a) This program is intended for healthcare professionals and is supported by an educational grant from Boehringer Ingelheim Pharmaceuticals Inc. and Eli Lilly Company.
Read 36 tweets
1/ Have you seen the New Non-Nutritive sweeteners paper in Cell making the rounds!?! Fantastic!

Here's a video rundown:

And this thread contains a brief tweetorial...
2/ This study took 120 young health people who didn't consume non-nutritive sweeteners (NNS) and broke them into 6 groups, n = 20/group
👉 Control (no supplement)
👉 Glucose
👉 Sacchrin
👉 Sucralose
👉 Aspartame
👉 Stevia
7 day baseline, 14 day exposure, and 7 day follow-up
3/ There was a clear individualized response across NNS, with Sucralose and Saccharin having the largest impact on glucose tolerance on oral glucose tolerance test.

There were "responders" (who had worse glucose tolerance in response to NNS) and also non-responders.
Read 11 tweets
If I went #vegan #keto for 3 weeks, do you think I’d still be #LMHR? @realDaveFeldman @siobhan_huggins @drscottyk @AlbertSyMD
1/ Okay, I'm putting a bow on this. And, short answer is... yes, the 37% have it. You can be on a 0 cholesterol #vegan #ketogenic diet and be #LMHR. Now for a debrief with some reflections. @realDaveFeldman @AlbertSyMD @siobhan_huggins @drscottyk ... Image
2/ First and foremost, what did my diet look like?

Vegan and w/o no coconut to maintain low sat fat % <15% total fat. These are data from a day of soy protein, 1/4c tahini, 1lb eggplant, 100g broccoli, 6 Tbsp EVOO, 4 Tbsp avo oil, 2 oz ea macadamia and pecans, 200g asparagus Image
Read 12 tweets
We are excited to share our new work @Nature with @ThaissLab, uncovering the impact of ketogenic diet and beta-hydroxybutyrate on colorectal cancer, led by @OxDmitrieva. (1/7)…
We screened different diets for their potential to inhibit the development of colorectal cancer, and found that ketogenic diets had the most potent effect, in collaboration with @SGrivennikov. (2/7)
Ketogenic diets induce hepatic ketogenesis, similar to long periods of #fasting. We found that the ketone body beta-hydroxybutyrate (BHB) was similarly protective against colorectal cancer as ketogenic diet. (3/7)
Read 8 tweets
Ketogenic Diets: Not For Everyone?
The potential association between elevated blood lipids and a high fat, low carb diet.

#ketogenic #keto #ketodiet #longevity
The notion that in some cases food can be a medicine rings true. For better or for worse, diet can change one’s physiology.

One of the more popular diets today is the high-fat, very low-carbohydrate diet, also known as a ketogenic diet.
In some, the ketogenic diet may help to ameliorate obesity and type 2 diabetes and positively affect problematic cardiometabolic markers.
Read 8 tweets
Brand New Data #keto #immune

#keto diet improves adaptive immunity through immunometabolic reprogramming without up regulating innate immunity

Basically: stronger immune system with less inflammation 🔥…
2/ #Ketogenic diet could also prove to be a valuable measure in the
threatening situation of the current #COVID-19 pandemic” ya, no kidding... in more ways than one
3/ “These new immunological aspects of KD might contribute to the modern concept of metabolic therapy of cancer (Seyfried et al, 2017, 2020). KD not only targets the Warburg effect, but could also
strengthen anti-tumor immunity (Ferrere et al, 2021).” .@Sam_Apple1
#sugar #cancer
Read 3 tweets
Returning from a trip to attend memorial services for a dear vegetarian friend who died of Cancer.

Almost everyone I saw has Cancer, too.

And they all say:

“Why am I sick? I eat such a healthy diet, mostly fruit, vegetables and plant based!”
When I suggest it might be a chronic lack of protein, B-12, carnitine, carnosine, minerals, collagen, saturated fats and iron...and too much sugar and oxalates they are in complete denial. #vegan #cancer #breastcancer Image
I ate a lot of hummus, nut butter, tahini, rice, vegetables and fruit. (To be polite.)

I secretly cooked steaks on a small stove I travel with.
Read 12 tweets

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