Rheum Cat Profile picture
Nov 11, 2022 10 tweets 8 min read Read on X
#ACR22 #ReviewCourse resuming with paraneoplastic syndromes in rheumatology
This is not an iRAE talk but the main points at the outset highlight the need to understand how to talk with our oncology colleagues to best treat patients with malignancy and rheumatic disease

#ACR22 #ReviewCourse
RS3PE:

If no pitting edema of the hands, think if this is the right dx!

#ACR22 #CourseReview
Palmar fasciitis & polyarthritis (there's a Thieves Market poster on this!)

palmar skin: 🌴woody texture

if no cancer found: limited benefit with steroids, DMARDs 💊

#ACR22 #ReviewCourse
Pancreatitis Panniculitis Polyarthritis

🦵panniculitis looks like E nodosum & occurs in lower extremities

more a/w acute pancreatitis than pancreatic ca

💊tx resistant; pred starting dose 40mg

#ACR22 #ReviewCourse
Hypertrophic osteoarthropathy

🩻a/w lung cancer; HRCT if resp sxs

🩻clubbing (distal phalanges)
🦵periostitis (tibia, fibula); can see knee effusions

#ACR22 #Reviewcourse
Eosinophlic fasciitis

👉usually idiopathic rather than paraneoplastic but can be a/w hematologic disorders

🔍don't need peripheral or tissue eosinophilia to make a dx

#ACR22 #ReviewCourse
Fascial enhancement on MRI (STIR sequence) that resolves with MTX treatment

CK for the most part nml; aldolase may be ⬆️

💊Prednisone first line
💊MTX if refractory

#ACR22 #REviewcourse
LCV: typically limited to the skin (palpable purpura, ulceration)

Erythromelalgia: a/w heme malignancy.
🔥Pain can be excruciating & burning

#ACR22 #Reviewcourse
What about the strength of association with malignancy risk?

Why does it matter? Because it affects:

👉How concerned we should be that there is an underlying malignancy

👉How hard should we look for an underlying malignancy

#ACR22 #ReviewCourse

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More from @rheum_cat

Nov 13, 2022
#ACR22 social media talk, very meta
Part 1️⃣: optimize your conference tweeting
If you're reading this you probably know all of this!

The first pro-tip was figure out the conference hashtag
The second? Engage with others in rheum
#ACR22
What else?

👉amplify your group
👉amplify speakers and sessions of interest
👉amplify your colleagues so they will amplify you in turn

#ACR22
Read 10 tweets
Nov 13, 2022
#ACR22 infection (COVID) posters Image
Abs 0784 @CCalabreseDO

Cleveland Clinic breakthrough infections, including data on n=21 who received Evusheld

📌Publication here: pubmed.ncbi.nlm.nih.gov/35791921/

#ACR22
@CCalabreseDO Abs 0779 @CCalabreseDO

Experience with evusheld PrEP with IMID on BCDT at Cleveland Clinic

📌Publication here: pubmed.ncbi.nlm.nih.gov/36123015/

#ACR22
Read 13 tweets
Nov 13, 2022
The EULAR e posters were tiny (bad) but speakers could zoom in and out (good)

That would have been nice for #IgniteTalks #ACR22
The sound is adequate though. EULAR issue was that the sound was poor in their (smaller) poster tour stages #ACR22 #IgniteTalk
Read 4 tweets
Nov 13, 2022
#ACR22 epidemiology posters Image
Abs 0700 @zach_wallace_md
💻Using NLP, ML algorithms to identify ANCA vasculitis cases

They also looked at the difference in performance metrics with/without filtering keywords

An explosion of NLP studies in rheum! #ACR22
@zach_wallace_md Abs 0732 Ho, et al. @JYazdanyMD @MilenaGianfran
💻Part of the explosion of NLP studies in rheum

Here the UCSF group aimed to capture VZV cases (differentiate from vaccination); and to capture active vs historical cases

See their diagrams explaining the steps!
#ACR22
Read 13 tweets
Nov 13, 2022
We have learned quite quickly that a virtual ONLY poster hall mixed into a hybrid meeting doesn't work well.

Poor wifi and the crashing platform compound the problem

And if it's online ONLY, is that truly hybrid?

#ACR22
This is not a complaint thread. I am hoping we can have discussion about what works/doesn't work, and what could be done next year for #ACR23
It goes without saying that an in-person poster hall is the most requested item on the wishlist for #ACR23

@GrantSchulert @Tuhina_Neogi
Read 5 tweets
Nov 13, 2022
Biostatician @MikeLaValley8 @BU_BMC_Rheum presents a quick overview on how to appropriately interpret results from studies #ACR22

Of course this is not an exhaustive deep dive, but covers some common errors of interpretation Image
@MikeLaValley8 @BU_BMC_Rheum First, what is your research question? What is the question you are trying to answer with t he study?

👉Does this exposure CAUSE this outcome?

#ACR22 Image
@MikeLaValley8 @BU_BMC_Rheum What are common observational study designs and what are big issues to watch out for?

These are issues that can affect the validity of their results.

There are more potential issues within these study designs that is beyond the scope of this table

#ACR22 Image
Read 15 tweets

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