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Federico Andres Lois Profile picture
@federicolois
Nov 25, 2022 • 14 tweets • 6 min read • Read on X
1/ Let me dispel some myths caused by credentialism statements like: "Trust me, I am a surgeon and I been doing this for decades".

First, there is evidence that they don't even work in the operating room. Image
2/ Let's start with the basics. Ritter et al. [1975] “the wearing of a surgical face mask had no effect upon the overall operating room environmental contamination.” Oops.
pubmed.ncbi.nlm.nih.gov/1157412/
3/ Ha’eri and Wiley [1980] they used albumin microspheres to the interior of the mask (source control) and they look for them in the OR and operating field. “Particle contamination of the wound was demonstrated in all experiments.” Mhhh.
europepmc.org/article/med/73…
4/ Laslett and Sabin [1989] “No infections were found in any patient, regardless of whether a cap or mask was used” onlinelibrary.wiley.com/doi/abs/10.100…
Bonus track: Sjøl and Kelbaek [2002] europepmc.org/article/med/11…
5/ Tunevall [1991] 1,537 surgeries with masks, infections in 4.7%. 1,551 surgeries without masks, infections in 3.5%. Double Oops!!!
link.springer.com/article/10.100…
6/ Skinner and Sutton [2001] “The evidence for discontinuing the use of surgical face masks would appear to be stronger than the evidence available to support their continued use.”
journals.sagepub.com/doi/pdf/10.117…
7/ Lahme et al [2001] “surgical face masks worn by patients during regional anesthesia, did not reduce the concentration of airborne bacteria over the operation field in our study. Thus they are dispensable.”
europepmc.org/article/med/11…
8/ Figueiredo et al. [2001] 5 years of peritoneal dialisis without face masks. Peritonitis rates at the unit no different than the ones found in hospitals that used face masks. advancesinpd.com/adv01/21Figuei…
Should I continue?
9/ Why shouldn't I, since there are so many more. Bahli [2009] “no significant difference in the incidence of postoperative wound infection was observed between masks groups and groups operated with no masks.”
semanticscholar.org/paper/Does-evi…
10/ Karolinska Institute [2010] “Our decision to no longer require routine surgical masks for personnel not scrubbed for surgery is a departure from common practice. But the evidence to support this practice does not exist,” wrote Dr. Eva Sellden.
pubs.asahq.org/anesthesiology…
11/ I don't want to bore you, but there is so much more. That is without even starting with pro-mask studies like the Syrian Hamsters that paradoxically show that the critters with higher viral load in the lungs are the masked ones.
Image
12/ Or aerosol exposure may lead to more severe illness. Triple Oops!!!

I understand MDs have lots of fluid and particulate dynamics classes about the physics of airborne particles in the nasopharynx.
13/ That is of-course without considering harms. Including potential exposure to carcinogenic substances.
14/ When someone, no matter how "credentialed", talks without evidence it is our duty to call BS on it. You know in the old age, they had been burning witches for ages until we realized that maybe it was not such a good idea. via @bobscartoons Image

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More from @federicolois

Federico Andres Lois Profile picture
Feb 10
1/ Alright, nerds buckle up. My read on todays news is @elonmusk playing 8D chess as usual. You have to hand it to him, he is smart as fuck. This isn’t just joking around trying to buy OpenAI. This is the AI industry’s version of Game of Thrones, and everyone’s got knives out.

Let’s break it down. 🧵👇
2/ First, OpenAI’s structure is a financial booby trap.

- There’s a nonprofit (OpenAI Inc.) that controls the for-profit OpenAI LP.
- That means you can’t just buy OpenAI outright—first, you gotta deal with the nonprofit board.
- It’s like saying, "I wanna buy Twitter," but the deal has to be approved by a secret society of monks.
3/ Musk’s move? Drop a $97.4 billion bid.

Now, did he actually wanna buy it? Probably not. This is a game theory 101 class onto adversarial games.

- If OpenAI rejects it, they must explain why, revealing their real motives.
- If they accept, Musk gets control and can shut down the Microsoft-aligned vision.
- If they try a legal loophole? He sues their pants off.

Either way, he wins.
Read 10 tweets
Federico Andres Lois Profile picture
Apr 24, 2024
1/ After almost 1.5 years of studying cancer research for personal reasons, I arrived at a realization that prompted me to write this tweet. I will lay out the hypothesis in this thread.
2/ Disclaimer: I am not a formally trained health researcher. More like a very curious and tenacious guy with a 15+ year background in research, development, & reproducibility in computer science (computer science).
3/ I am putting the hypothesis out there because it may make sense to others doing field work. Feel free to dissect this hypothesis, find holes in it, and play devil's advocate. We will all come out smarter from it.
Read 33 tweets
Federico Andres Lois Profile picture
Jan 3, 2024
1/ There is a very perverse dynamic on how Chavism (aka "the communist socialism") works. Let's use Argentina as the example. Over the first 20 years they initiate a process that we could call "Earnings Substitution" that will seal your fate over time.
2/ Your earnings/salary is going down and at the same time "subsidies" start to go up in order to fool people into think that nothing has changed. This works because the dirty job is done by inflation which is a much slower process.
3/ By the time people starts to realize that something is wrong, because some critical goods are not available (medicine, food, you name it) or inflation enters a death spiral; most people already depend on subsidies for spending.
Read 6 tweets
Federico Andres Lois Profile picture
Aug 2, 2023
1/ Recently some interesting papers have been doing the rounds in the health community. To me the most interesting ones have been the GlyNAC paper and the more recent Taurine deficiency as a driver of aging papers.
2/ Disclaimer: While I have been researching this for a year and even executed an experimental protocol tailored for myself based on the GlyNAC paper, I am NOT a health professional, and I am just taking my health into my own hands. This is not advice of any kind.
3/ Disclaimers aside, why do I think these 2 papers are interesting? First because the claim (if true) is a game changer. And second because they may be related but I haven’t seen this relationship spotlighted by anyone.
Read 14 tweets
Federico Andres Lois Profile picture
Apr 1, 2023
This just confirmed the weaponization of block lists. If enough people/bots block and mute you, they are essentially cancelling you. I find lots of people with I have never interacted with that has me blocked. Assuming there are third party block lists and block networks.
Normally that is an issue in general. Anyone that has done reinforcement learning had figure out (usually in the worst way) that you have to be incredible cautious with penalties. They are very prone to be gamed.
More on the issue:
Read 4 tweets
Federico Andres Lois Profile picture
Mar 20, 2023
1/ I asked #GPT4 to review our paper with @LDjaparidze. This is what happened and what I learned in the process. medrxiv.org/content/10.110…
2/ Since the general problem that practitioners find (in the worst way) is always training set tainting (guilty-as-charged). Habits die hard, the first thing I did is asking to do a review of the paper without any extra knowledge about what the paper says
3/ From the response alone I learned 2 things. First, our paper title was deadly accurate. I also learned that it has no information whatsoever on it, as the entire response can be generated from understanding the title itself.
Read 10 tweets

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