More from @TuckerGoodrich

Tucker Goodrich

@TuckerGoodrich

Nov 13

1/ "Only a few previous studies have examined head-to-head the extent of excess risk explained through high concentrations of remnant cholesterol or triglycerides (substitute markers for high VLDL cholesterol) and high concentrations of LDL cholesterol separately...

2/ "...(18, 19), and none have used directly measured concentrations of both VLDL cholesterol and LDL cholesterol. Consequently, it is presently unknown to what extent directly measured cholesterol in large and small VLDLs, in IDL, and in LDL in head-to-head comparison...

3/ "...each explain excess risk of myocardial infarction in individuals with obesity."

This is from 2021, mind you. 🙄

Read 7 tweets

Tucker Goodrich

@TuckerGoodrich

Nov 6

Can we trust PhDs?

1/ Claim: "No upper limit (UL) has been set for linoleic acid because of a lack of a defined intake establishing adverse affects (2)."

Reference 2: “An upper boundary for linoleic acid is set at 10 percent of energy for three reasons: ...(3) high intakes

@MDVilntfluid

2/ "...of linoleic acid create a pro-oxidant state that may predispose to several chronic diseases, such as CHD and cancer."

Read both snapshots.

Hat tip to @MDVilntfluid for getting me to take another look at Whelan.

#lcl6

3/3 Claim in: "Linoleic Acid" doi.org/10.3945/an.113…

Ref 2: "Dietary Reference Intakes for ...Fat, Fatty Acids..." nap.edu/catalog/10490/…

Read 5 tweets

Tucker Goodrich

@TuckerGoodrich

Oct 17

#COVID19 wasn't bad enough. This is #Fauci's parting gift...

1/ "We generated chimeric recombinant SARS-CoV-2 encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate and compared this virus with the naturally circulating Omicron variant..."

2/ "The Omicron S-bearing virus robustly escapes vaccine-induced humoral immunity, mainly due to mutations in the receptor-binding motif (RBM), yet unlike naturally occurring Omicron, efficiently replicates in cell lines and primary-like distal lung cells."

3/ "In K18-hACE2 mice, while Omicron causes mild, non-fatal infection, the Omicron S-carrying virus inflicts severe disease with a mortality rate of 80%."

Read 6 tweets

Tucker Goodrich

@TuckerGoodrich

Oct 5

@haidut

1/ So apparently one thing folks didn't like about my discussion with @haidut was my bringing up the subject of organ failure with a low-fat, low-calorie, high-carb diet. (according to the Youtube comments, anyway.)

https://twitter.com/DavidGornoski/status/1575144807571259392

2/ So:

"After 8 weeks of dieting sludge was detected in 3 subjects and gallstones in 13(25.5%). In contrast, none of the nondieting subjects developed any detectable gallbladder abnormalities.

3/ "We conclude that this form of weight-reduction dieting predisposes to the development of gallstones and that gallstone formation is a risk of this type of prolonged calorie restriction.

Read 8 tweets

Tucker Goodrich

@TuckerGoodrich

Oct 5

@ZeroAcreFarms

1/4 Canola (rapeseed) oil is one of the better seed oils, it's ~20% linoleic acid.

But it still goes rancid (toxic), because it contains linoleic acid.

Safest and healthiest fats/oils to eat are low in linoleic acid!

@ZeroAcreFarms #lcl6

2/4 "Triacylglycerol (TG), the main component of edible oil, is oxidized by thermal- or photo- oxidation to form TG hydroperoxide (TGOOH) as the primary oxidation product.

3/4 "Since TGOOH and its subsequent oxidation products cause not only the deterioration of oil quality but also various toxicities, preventing the oxidation of edible oils is essential."

Read 4 tweets