Last week, Julia Belluz (@juliaoftoronto) published an article not on what #obesity is, but what it isn't: a personal failing. In it, she argues that obesity is not one thing, it's many. That's right. It's not OBESITY. It's OBESITIES.
nytimes.com/2022/11/21/opi…
nytimes.com/2022/11/21/opi…
This week, my colleague Ilene Fennoy and I published a paper delineating the history of all of these obesities. Nonetheless, people still argue whether obesity is a problem of energy storage (#insulin) or a problem of energy balance (#calories).
karger.com/Article/FullTe…
karger.com/Article/FullTe…
Because both are true. One set of causes (insulin, cortisol, genetics, obesogens) are a problem of energy storage. Another set of causes (nutrition, sedentariness, addiction, epigenetics, microbiome) are a problem of energy balance.
So let's get past this roadblock. Different obesities are due to different mechanisms and call for different strategies for treatment and prevention. But the one cause that transcends both energy storage and energy balance is sugar. Because #sugar is a mitochondrial toxin.
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