Thread by @chydorina

"Covid-19 and Ehlers-Danlos syndrome: the dangers of the Spike protein of SARS-CoV-2"

Looks like there IS increased risk for #hEDS and #EDS and not just from Covid itself but also from the mRNA vaccine.

docs.google.com/document/d/1cn…

@remissionbiome #MECFS #LongCovid

@remissionbiome 1. Jean-Marc Sabatier – Although EDS is a rare genetic pathology, with an overall incidence of around 1 in 5,000 people (highly variable incidence depending on the type of EDS), I have observed that a very high number of people suffering from the most severe forms of long Covid

@remissionbiome 2. (post-infection or post-vaccination sequelae) had EDS. As mentioned earlier, EDS is systemic and directly linked to abnormalities in the connective tissue of genetic origin (production of collagen). It seems to me quite possible that the deficiency in proteins of

@remissionbiome 3. the extracellular matrix - which target membrane integrins - confers an exacerbated "sensitivity" to the viral or vaccine Spike protein also capable of targeting integrins, potentially leading to cell death, via caspase-3 or other activation.Notably, the Spike protein

@remissionbiome 4. binds to alpha-5 beta-1 and alpha-V beta-3 integrins, which are integrins also targeted by collagen (partially denatured exposing its cryptic/hidden RGD motifs) deficient in people with EDS. Thus, it seems to me that any anti-Covid-19 vaccination booster for

@remissionbiome 5. these high-risk people is not desirable, the benefit/risk balance being extremely unfavourable. In the event of SARS-CoV-2 infection, early outpatient treatment (eg high vitamin D supplementation) of these people seems appropriate.

@remissionbiome No peer-review studies yet as far as I can tell but all of this makes to anyone with a basic understanding of EDS. Studies that support these observations and links will probably start showing up soon.

@remissionbiome Huge thank you to @karenlubell and @renesugar who dug this up. I just made it into a google doc for easier dissemination.

@remissionbiome @karenlubell @renesugar

https://twitter.com/karenlubell/status/1612591541914304512