Thread by @TumorBoardTues

1/#TumorBoardTuesday #OncTwitter

🗓️TODAY🗓 w @DrMMurphy & @DrTeplinsky
🎥#EndometrialCancer - Mnging TKI/IO AEs

#CMEℹ️ bit.ly/3Vqtabi
Support by edu grants from Eisai & @Merck

🚨Be ready @ 8p ET/5p PT
✅Answer #PreTest👇
🔁RT & tag 🩺

🟢Where r u in your career?

2/#TumorBoardTuesday #OncTwitter #GynCSM #gynonc
#CME🔗bit.ly/3YRDkog

🟢#PreTest Q 1️⃣
📊Diarrhea, nausea, & vomiting are common GI toxicities associated w pembro + lenvatinib combo therapy

🟢Which other tox may occur if these GI toxicities are not effectively managed?

3/#TumorBoardTuesday #GynCSM #EndometrialCancer
#CME🔗bit.ly/3YRDkog

🟢#PreTest Q 2️⃣
📊During tx w pembro + lenvatinib, pt develops grade 3 diarrhea
🛑Lenva held
💊Loperamide Rx
Grade3️⃣diarrhea persists

🟢What is the next step for this pt?
(cs=corticosteroid)

4/#TumorBoardTuesday #GynCSM
🟢#PreTest Q 3️⃣

📊Pt receiving pembro + lenva combo for past 12m
🗓@ f/u presented w persistently high levels of TSH
🟥Lenva withheld, but TSH levels remain high (>10mIU/L)

🟢What is the most appropriate next step in the mgmt of this pt?

5/#TumorBoardTuesday #BonumCE #OncTwitter #GynCSM #gynonc #EndometrialCancer
#CME 🔗bit.ly/3YRDkog

🟢#PreTest Q 4️⃣
📊During treatment w pembro + lenva, pt develops grade 3 HTN
🟢What is the most effective mgmt strategy for this patient? (CS = corticosteroid)