Ashish M. Kamat, MD, MBBS Profile picture
Jan 21, 2023 11 tweets 24 min read Read on X
Help our debaters prep with your responses
Poll #1a: Does PDD/NBI etc help alter natural history of NMIBC?

@joanfundi @MarekBabjuk
Poll #1b: Do we still need random biopsies in era of PDD/NBI?

@MarekBabjuk @joanfundi
Poll #2: Should we be switching to en block TURBT for all bladder tumors?

#bladdercancer @paolo_gontero @JoshMeeks @bbmdmsk @joanfundi @MarekBabjuk @joostboormans @spsutkaMD @siadaneshmand @jteoh_hk
Poll #3b: in above scenario; does variant histology change your recommendation? (assume micropapillary, 15% specimen)

@priyaraomd @MaxKates @SWilliams_MD @WesKassouf @JanetKukreja @Agarwal_CaB @PatrickKenneyMD @evacomperat @h_alahmadie @MattGalsky
Poll #4a: In young healthy patient, is prostate sparing radical cystectomy a safe option for MIBC?

@angiesmith_uro @ParamMariappan @RenuEapen @Svet_MD @garysteinbergmd @JimCatto @uretericbud #bladdercancer @bcan_chisolm
Poll #6: Is there a role for local therapy to the bladder in patients with oligometastatic disease?

@AndreaNecchi @EfstathiouEleni @nnavai @UroCancer @PGrivasMDPhD @siadaneshmand @bbmdmsk @MarekBabjuk @joanfundi @MRoupret @mouwlab @Prof_Nick_James @achoud72 @drtanws

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More from @UroDocAsh

Apr 22
Bladder preservation in muscle-invasive bladder cancer (MIBC) is evidence-based, patient-centered, and underutilized

The latest @IBCG_BladderCA consensus in @EUplatinum offers global expert recommendations on when, how, and for whom bladder-sparing strategies are appropriate 🧵1/5

#BladderCancer #AUA25 #OncSurgery #PatientCenteredCare @shilpaonc @achoud72 @FaltasLab @mouwlab @AndreaNecchi @PGrivasMDPhD @UrogerliMD @danielgrassImage
🏛️ The backbone of bladder preservation is Trimodal Therapy (TMT):
🔹 Maximal TURBT
🔹 Radiation therapy
🔹 Concurrent chemo (cisplatin, 5-FU + MMC, gemcitabine, or carbogen + nicotinamide)
TMT can offer survival outcomes on par with cystectomy for well select patients @AlisonBirtle @Prof_Nick_James @Uromigos @scserendipity1 @DrFelixGuerrero 🧵2/5
@IBCG_BladderCA @EUplatinum @siadaneshmand @pjhensley11 @nnavai @JanetKukreja @WesKassouf @DrRosenbergMSK @urotoday @SWilliams_MD @TomFlaigMD @BladderCancerUS Who qualifies for TMT?
✅ Unifocal cT2 tumor
✅ No multifocal CIS
✅ No hydronephrosis
✅ Good bladder function
❗But even patients with cT3, CIS, or hydronephrosis should not be automatically excluded -> salvage RC is still option 🧵3/5 Image
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