Jeff Gilchrist Profile picture
Jan 23, 2023 42 tweets 13 min read Read on X
Real life example of impact from COVID infection and why we need clean air

@ahandvanish taught a grad course on generative music at NYU, works with machine learning, data sonification (auditory equivalent of data visualization), and more ( hannahishere.com/about-me/ ). 🧵1/ Photo of Hannah Davis. Imag...
An unrolled one-page web view for this long thread that may be easier to read or share can be found here ( ). 2/
Hannah Davis was recognized by Time Magazine as one of the 100 rising stars from across industries and around the world for 2022 ( time.com/collection/tim… ). 3.
@ahandvanish was also brave enough to share her real-life experience of COVID infection that drastically impacted her processing speed ( ). 4/
She happened to have done some neuro testing just before her COVID infection where she scored being faster than 96% of people. 5/
After her COVID infection, she started having brain issues and decided to redo the test again where she found out her processing speed had dropped from top 96% of people down to only faster than 14% of people. 6/ Graph showing processing sp...
Hannah explains in her thread how low processing speed affects everything from basic communication with people (talking, texting) not only in how long it takes but how much information you understand about what you are reading/hearing. 7/
This unfortunately makes relationships harder to maintain. She goes on to describe how actions that require you to make fast decisions such as driving are much scarier or often not possible to do at all. 8/
Even common sense decision making is related to processing speed and can be difficult. 9/
Processing speed also impacts memory by limiting how fast you can register memories and emotional awareness in how long it takes to know how you are feeling. Low processing speed ultimately impacts identity in a serious way. 10/
"Processing speed impacts how much you can hold in your head, how you weave the world together and make sense of it, the thoughts that come up when you think about the people, places, ideas that you love. It turns those processes into just a void, a blank wall." 11/
Hannah Davis wants people to understand what can happen after you become infected with COVID and how much #LongCOVID can change you, potentially permanently. This is not just a "mild" virus and should not be treated as such. 12/
Long COVID is not just happening to her or a small number of people, but it is estimated that at least 65 million people worldwide have Long COVID with cases increasing daily. 13/
Hannah Davis and others have put together and published major findings, mechanisms and recommendations on the subject ( nature.com/articles/s4157… ). 14/
This is why it is so important that we improve the infrastructure to provide clean air like we did for water to end the cholera epidemics two centuries ago ( thetyee.ca/Analysis/2023/… ). 15/
Unfortunately we can't easily see how dirty the air is and in many locations including schools and workplaces but if you could see the air in some places, it would look more like the left glass of water compared to the right glass of water ( ). 16/
Would you drink the glass of water on the left? If not, why are you still breathing in dirty air in poorly ventilated indoor spaces? 17/ Image of glass on the left ...
If spaces are not being regularly tested and monitored, you may have no idea how clean (or not) the air is that you are constantly breathing in or if equipment is actually functioning properly. 18/
For example, look at these two Corsi-Rosenthal (CR) boxes and how dirty the filters got in a school after 7 months despite have windows open 95% of the time and CO2 levels below 1200 ppm ( ). 19/ Image of two Corsi-Rosentha...
They were still removing that much crap from the air that otherwise would have been breathed in by our children and the teacher. 20/
Do you commute to work using the subway? Check out how dirty the filter on this respirator got (compared to the brand new clean one beside) after a few months taking the subway 2-3 times a week ( ). 21/ Image of a Prescient-X Brea...
People not wearing a respirator are all breathing this into their lungs every day they commute. 22/
We breathe so much more air (11,000L) than we drink water (4L) or consume food (2L) every day so it is even more important that we ensure we are breathing in clean air ( nasa.gov/mission_pages/… ). 23/
This image really helps you understand the relative difference in the amount ( ). 24/ Graphical representation of...
Did you know if you measure the amount of CO2 in an indoor space you can actually calculate how much of other people's exhaled breath you are breathing in? This handy calculate will help you ( docs.google.com/spreadsheets/d… ). 25/
I have seen some school classrooms measure higher than 3,000 ppm of CO2 which means all of those children are breathing in 28.3 liters of other people's breath every hour! 26/
Can you imagine yourself or your child breathing in the equivalent of 14 bottles of pop full of other people's air backwash every hour? 27/ Image of a 2L bottle of pop...
If you think it too hard to upgrade the infrastructure in current schools and buildings, Engineers are up for the challenge. They raised entire cities (Chicago, Seattle) almost 175 years ago to combat harmful pathogens ( ). 28/
Would improving ventilation actually help? A study in Italy actually found classrooms equipped with mechanical ventilation systems decreased the relative risk of COVID infection by at least 74% compared to classrooms with only natural ventilation ( frontiersin.org/articles/10.33… ). 29/ Graph comparison between th...
For classrooms that were able to obtain higher than ventilation rates greater than 10L per second per student, risk of infection decreased even further to at least 80% lower. 30/
Cleaner air not only reduces the risk from COVID infection but all other viruses that transmit in aerosols through the air like influenza and other respiratory viruses. Click "Show replies" 👇 to continue. 31/
This is important as there have also been links found with other viruses that significantly increased the risk of neurodegenerative disease ( cell.com/neuron/fulltex… ). H/T: @DFisman 32/ Graphical summary of hazard...
Even influenza with pneumonia was significantly associated with five of the six neurodegenerative diseases studied and some exposures were associated with an increased risk of neurodegeneration up to 15 years after infection. 33/
Are you sure you want to keep getting infected by multiple viruses each year if you don't have to? 34/
Remember, as we saw above, clean indoor air isn't just about COVID, but it can help protect against other pathogens and air pollutants linked to various health problems which you can learn more about here ( ). 35/
Ventilation is also important when cooking as harmful particulate matter (PM) particles can be generated and breathed in so please remember to turn on your kitchen fan when cooking if you have one. 36/
I was able to measure PM2.5 particle levels were 10x higher when I was frying vegetables on my induction stove with the range hood fan turned off using a CO2.click Model E IAQ monitor that was 7.6m (25 feet) away in our family room ( co2.click/ecommerce/en/M… ). 37/ Graph showing particulate m...
If you don't have a hood fan, a HEPA filter or Corsi-Rosenthal (CR) box may help reduce PM in your kitchen as well. You can learn how to build your own CR box here ( ). 38/
If you aren't sure how the filters in air cleaners or masks actually block viruses and other particles that are much smaller than the sizes of the holes in the filtering material, this thread explains *how* they do that ( ). 39/ Image visualizing the Relat...
If you want to read about another real-world example of the impact of COVID infection but this time from cardiovascular complications you can find that here ( ). 40/
The wealthy also believe it is important to clean the air of indoor spaces as they went out of their way to do for the recent WEF conference in Davos, Switzerland. The conference space before was not good enough so they upgraded it to be #DavosSafe ( ).41/
A real-world example of a young woman 28 years old disabled from the pandemic, infected in March 2020 before the vaccines were available with only a mild illness at first but then she never got better ( thetyee.ca/Analysis/2023/… ). 42/

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More from @jeffgilchrist

Jan 20
Similar to #Canada, babies in the #UK are at higher risk for #hospitalization and #ICU admission from #COVID. Their data looks deeper at infants < 6 months old which have higher ER attendance, hospital admission and severe hospitalisation rates than the oldest adults 90+! 🧵1/
That data from the UK was taken from this pre-print study ( ). 2/medrxiv.org/content/10.110…
In Canada, babies < 1 years old had the highest ICU admission rates of all age groups from Aug. 27, 2023 to Aug. 24, 2024. Read on to see more details including Flu and RSV too ( ). 3/
Read 7 tweets
Jan 19
The @elastomaskpro () is a NIOSH approved reusable N95 elastomeric respirator. It is made of silicone so a higher chance it will fit and seal well and is super breathable at the same time. Read on to find out more about my experience with it. 🧵1/ elastomaskpro.comA blue respirator mask, called ElastoMaskPro, rests on top of a blue and white box. The mask has a smooth, curved design with two circular filters on each side. The mask's straps are neatly arranged.
A light blue ElastoMaskPro N95 reusable respirator mask with a soft, flexible facepiece rests on top of its packaging box. The mask features a large opening in the center, showcasing white pleated filters. Two elastic straps are attached to the mask for securing it to the face.
Full disclosure: ElastoMaskPro sent me a unit to evaluate. There were no strings attached, they just asked that I provided feedback after I tried it. This thread is the first time they are seeing my feedback, they did not review anything before it being posted here. 2/
The ElastoMaskPro is very cost effective at the current sale price of $29.99 which includes two N95 filtering pucks. You can continue using the filters until they either get too dirty or there is increased breathing resistance. 3/ ElastoMaskPro Filter Puck. Filter Pucks are constructed using an adhesive-free process that incorporates a large volume of long-lasting, highly durable mechanical filtration media.
Read 43 tweets
Jan 6
#Ottawa, #Ontario, #Canada Virus Update:

Ottawa updated its #respiratory #virus data again after a break for the holidays, respiratory related ED visits are up especially in kids 0-3, then 4-11 and age 80+. 🧵1/ A line graph showing the number of respiratory-related emergency department (ED) visits per 100,000 population by week, from September 1, 2023, to November 1, 2024, across different age groups. Six lines represent the age groups: Age 0-3 (purple), Age 4-11 (blue), Age 12-17 (green), Age 18-54 (yellow), Age 55-79 (red), and Age 80+ (orange). The Age 0-3 group shows the highest number of visits, peaking around 1000 visits per 100,000 population, while other age groups generally have rates below 250 visits per 100,000 population. The graph exhibits seasonal fluctuations, with peaks in the wint...
Quite a mixture of different viruses testing positive in the lab right now so people can pick up a variety of bugs in the air. 2/ A stacked area chart displaying the percentage of positive tests for various viruses over time, from October 1, 2022, to December 22, 2024. The x-axis represents weeks within this period, while the y-axis represents the percentage, cumulatively stacked to 100%. The chart features the following viruses, each depicted in a distinct color: COVID-19 (red), Entero/Rhinovirus (yellow), Seasonal human coronavirus (blue), RSV (green), Parainfluenza (purple), Influenza B (light blue), Influenza A (light green), Human metapneumovirus (pink), and Adenovirus (dark blue). COVID-19 maintains a high posit...
New hospitalizations also jumped a lot in the last two reporting weeks, not just due to #RSV but a big spike in #COVID as well.

Follow the latest updates here ( ). 3/ covid.gilchrist.ca/Ottawa.htmlThe bar chart shows the number of new hospitalizations per week in Ottawa from August 27, 2023, to December 22, 2024. The y-axis represents the number of patients, ranging from 0 to 100. The x-axis represents the weeks. The bars are color-coded: blue for COVID-19, purple for Influenza, and teal for RSV. The chart shows fluctuations in hospitalizations, with peaks around late 2023 and early 2024, and another peak towards the end of 2024.
A line graph displaying the percentage of patients hospitalized due to COVID-19, Influenza, or RSV over time, from September 1, 2023, to December 22, 2024. The x-axis represents weeks within this period, and the y-axis shows percentages from 0% to 100%. The graph has three colored lines: blue for COVID-19, purple for Influenza, and teal for RSV. COVID-19 consistently shows the highest percentage of hospitalizations, with fluctuations throughout the period.
Read 4 tweets
Dec 24, 2024
#Variant update for #Ontario, #Canada (to Dec 10, 2024)

The KP.3.1.1 #DeFLuQE variant has finally been surpassed with XEC now in top place above 20% while the other 5 (MC.* and XEC.* descendants) remain < 7%. Graph tools by @Mike_Honey_ 🧵1/ A line graph showing the lineage frequency of the top 7 COVID-19 genomes in Ontario, Canada, up to December 10, 2024. The graph includes data from 4,928 sequenced genomes. The x-axis represents dates from October 27 to December 08, while the y-axis represents lineage frequency percentages from 0% to 35%. Different colored lines represent different genome lineages: KP.3.1.1 (blue), MC.1 (green), MC.13 (purple), MC.16 (pink), MC.24 (orange), XEC (brown), and XEC.8 (yellow). Below the main graph, there is a bar chart showing the number of samples (n) collected each day, ranging from 0 to 200 s...
XEC is a combination of KP.3.3 and KS.1.1 that recombined together. MC.1 is a direct descendant of KP.3.1.1 with one spike mutation at T571I. To learn more about how variant naming works, you can read this article I wrote with @paulseaman31 ( ). 2/docs.google.com/document/d/1q0…
This Sankey graph shows the proportion of variants from PCR test genomic sequencing in Ontario since October 27, 2024. You can follow the lineage backwards to see where a variant is a descendant from. 3/ The Sankey diagram visually displays the evolution and distribution of sequenced genomes in Ontario, Canada, up to December 10, 2024. The diagram uses colored bars and curved lines to show the flow and relationships between different genome variants over time. Each variant is labeled, such as "XEC," "BA.2," "BA.2.86," "JN.1," "KP.3," and various sub-variants. These bars and lines illustrate the transitions and derivations from one variant to another. The total number of sequenced genomes depicted is 4,928. This visualization helps to underst...
Read 16 tweets
Dec 22, 2024
Population rate vs raw numbers

This is a good example of why it is useful to understand the importance of population *rate* and not just look at raw numbers. The first graph shows raw numbers and the second graph population rate. 🧵1/ #ED #Respiratory #Virus #Population #Ottawa Chart of Respiratory Related ED Visits by Week and Age (Ottawa, ON, Canada) with raw numbers
Chart of Respiratory Related ED Visits by Week and Age (Ottawa, ON, Canada) with population rate per 100K
Ottawa Public Health makes only the raw data available for All causes and respiratory-related emergency department visits to Ottawa hospitals by age group and week ( ). 2/open.ottawa.ca/datasets/ottaw…
If I take the data and plot all the ages together, you can at least see all of the age groups at the same time but it is just the raw numbers. 3/
Read 12 tweets
Dec 17, 2024
This is amazing, not only a lower cost CPC for measuring mask fit and ultrafine particles in a room, but also a new probe to measure fit of a respirator without destroying it, check out the video from @OpenAeros and @masknerd to see how it works ( ). 🧵1/ Woman wearing N95 head band respirator inserting new probe design in side of respirator so you don't have to puncture the front, the new OpenAeros OpenCPC machine operating on the table showing the ultrafine particle levels and Aaron Collins (@masknerd) holding the new blue probe against his face to show what it looks like.
@masknerd also demonstrates how you can use OpenCPC to measure how well an air cleaner is filtering particles when you insert the probe into the output vent where particles dropped to 6.4/cm^3 from the regular 700-800/cm^3 for the room. 2/ Aaron Collins (@masknerd) holding the OpenCPC probe inside the fins of a portable air cleaner to measure particle concentration showing it has dropped significantly.
When Aaron Collins moves the probe to a couple of feet in front of the portable air cleaner, levels go back up to 785/cm^3 which is the same as the room concentration indicating this type is filtering the air but doesn't create a "clean bubble" in front of it. 3/ Aaron Collins (@masknerd) holding the OpenCPC probe a couple of feet in front of a portable air cleaner to measure particle concentration, showing it has gone back up to room concentrations.
Read 6 tweets

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