1/4 Interesting study regarding #LDL-C vs all cause mortality*
✅NHANES -- so it's #OpenScience 👏
✅Lowest LDL-C associates with highest ACM
⚠️ No short term censoring (more on this below)
(*had in my reading list, but forgot until ht
@BobJohnson462) nature.com/articles/s4159…
✅NHANES -- so it's #OpenScience 👏
✅Lowest LDL-C associates with highest ACM
⚠️ No short term censoring (more on this below)
(*had in my reading list, but forgot until ht
@BobJohnson462) nature.com/articles/s4159…
2/4
A couple notes...
1️⃣ Many assume the higher ACM associated with LDL-C is due to "reverse causality". It's a hypothesis, to be sure, but one I think worth exploring.
Thus, it would have been ideal of the authors tried at least one or more analyses censoring 2-3 years.
A couple notes...
1️⃣ Many assume the higher ACM associated with LDL-C is due to "reverse causality". It's a hypothesis, to be sure, but one I think worth exploring.
Thus, it would have been ideal of the authors tried at least one or more analyses censoring 2-3 years.
3/4
2️⃣ As always, be aware these data are observational.
And as I say often👇
(Always worth a mention of Bradford Hill and his criteria, btw)
2️⃣ As always, be aware these data are observational.
And as I say often👇
(Always worth a mention of Bradford Hill and his criteria, btw)
https://twitter.com/realDaveFeldman/status/1500482422164504577?s=20&t=io36HL5D34UszTRMZqhYoA
4/4 Lastly, you may want to check out my most recent analysis on NHANES where I counted up the centenarians in the current data.
And to be sure, this has a massive amount of early death censoring (15-20 years!)
And to be sure, this has a massive amount of early death censoring (15-20 years!)
https://twitter.com/realDaveFeldman/status/1595197619310993408?s=20&t=io36HL5D34UszTRMZqhYoA
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