Lea Alhilali, MD Profile picture
Feb 13, 2023 12 tweets 6 min read Read on X
1/Do you know all the aspects of, well, ASPECTS?

Many know the anterior circulation #stroke scoring system—but posterior circulation (pc) ASPECTS is often unknown

Here’s a #tweetorial to help you remember pc-ASPECTS
#medtwitter #neurotwitter #meded #neurorad #neurology #FOAMed Image
2/Many know anterior circulation ASPECTS. It uses a 10 point scoring system to semi-quantitate the amount of the MCA territory infarcted on non-contrast head CT.

If you need a review: here’s my tweetorial on ASPECTS: Image
3/But it’s only useful for the anterior circulation. Posterior circulation accounts for ~25% of infarcts. Even w/recanalization, many of these pts do poorly bc of the extent of already infarcted tissue. So there’s a need to quantitate the amount of infarcted tissue in these pts Image
4/Posterior circulation ASPECTS, or pc-ASPECTS for short, is also a 10 point system—but for the vertebrobasilar circulation. Patients get points for each region NOT infarcted on the initial CT. Image
5/Similar to anterior ASPECTS, points are GOOD

It’s like a city—when a region infarcts, it is like the lights go out in that city region (literally, tissue darkens on CT)

In ant & post ASPECTS, you are counting the regions where the lights are still on—so high ASPECTS is good Image
6/Which regions get scored?

The biggest prognostic factors in posterior strokes are time & amount of already infarcted tissue.

So my mnemonic to remember pc-ASPECTS regions is:

Time & Mortal Brain decide Posterior Circulation Outcomes
(mortal brain= infarcted brain) Image
7/How do you assign points?

It’s a little different than anterior ASPECTS, where every region just got one point

For pc-ASPECTS, think of it like a mother. She only has 2 arms. So if there are two kids, they have to split the arms—only one arm can be wrapped around each kid Image
8/So unpaired structures, like the brainstem, are like having only one kid—you get both arms wrapped around you = 2 arms = 2 points.

If the structures are paired, like the cerebellum, it’s like having two kids--they must split the arms. Each gets only 1 arm = 1 point Image
9/So lets go through our regions using the mnemonic.

Each thalmus is worth only 1 point, bc they’re paired & have to share their mother’s arms.

The unpaired midbrain is worth 2 points (gets both arms) Image
10/Pons is unpaired, so it is worth 2 points.

But the paired cerebellar hemispheres & occipital cortex are each only worth 1 point per side, as each side claims only one of the mother’s arms Image
11/While there’s evidence that higher pc-ASPECTS means poorer outcome, there’s no consensus about what pc-ASPECTS score definitively confers a UFO (unfavorable outcome).

But the consensus about what confers a UFO in anterior circulation ASPECTS may change soon as well! Image
12/So now you know the regions & scoring for pc-ASPECTS!

Remember, the anterior circulation isn’t the only aspect of ASPECTS! Image

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More from @teachplaygrub

Sep 15
1/Time is brain!

So you don’t have time to struggle w/that stroke alert head CT.

Here’s a thread to help you with the CT findings in acute stroke! Image
2/CT in acute stroke has 2 main purposes

(1) exclude hemorrhage (a contraindication to thrombolysis)

(2) exclude other pathologies mimicking acute stroke. But you can also see other findings to help diagnosis a stroke. Image
3/Infarct appearance depends on timing.

In first 12 hrs, the most common imaging finding is…a normal head CT

However, you may see a hyperdense artery or basal ganglia obscuration. Later, you see loss of gray white differentiation & sulcal effacement Image
Read 13 tweets
Sep 12
1/Do you feel there’s a back-log of findings in a spine MRI report?

Everyone talks about discs & facets, but not everyone talks about the endplates

Do you?

Do you need to talk about degenerative changes (Modic changes) of the endplates?

Here’s thread w/all you need to know! Image
2/Over 30 years ago, Modic et al. found there were 3 types of degenerative endplate changes:

(1) T2 bright changes (indicating edema, Modic 1)
(2) T1 bright changes (indicating fat, Modic 2)
(3) T1 & T2 dark changes (indicating sclerosis, Modic 3)

But what do they mean? Image
3/Let’s start w/Modic 1.

These are bright on T2, indicating edema

On pathology, it’s what you’d expect w/edema: inflammation, vascular granulation tissue, & high cellular turnover

Vascular granulation tissue means these can enhance on post contrast images—mimicking discitis! Image
Read 18 tweets
Sep 10
1/Are you FISHING for a way to better evaluate subarachnoid hemorrhage?

Are you hungry for a way to classify these patients?

Donut you worry!

Here’s a short thread to help you remember the modified Fisher scale for classifying subarachnoid hemorrhage. Image
2/Just think of the brain as a donut. Like a donut, it’s a bunch of stuff around a hole in the middle.

Ventricles are the hole in the middle of the brain just like there’s a hole in the middle of the dough in a donut.

Just don’t quote me to your neuroanatomy professor…. Image
3/Subarachnoid hemorrhage (SAH) added to the brain makes it less healthy, the same way adding toppings to a donut makes it less healthy.

Increasing severity of SAH is like increasingly unhealthy donut toppings. Fisher scale quantifies the vasospasm risk for increasing SAH Image
Read 8 tweets
Sep 8
1/Talk about twisting your back!

Do spine vascular lesions make your brain feel as tangled as the dilated vessels you see?

Want some more information on malformations?

Here’s a thread on spine vascular anatomy to give you durable knowledge on dural arteriovenous fistulas (dAVF)Image
2/To understand spinal dural AVFs, you need to understand basic spinal vascular anatomy.

The spine is LONG—to get blood from the top to the bottom is like going through the length of a marathon course Image
3/So we will need to tackle it like you tackle running a marathon.

When you run a marathon, you replenish yourself at aid/water stations along the way so you can make it all the way through.

Same w/spinal arterial vasculature—it needs to be replenished on the way down. Image
Read 19 tweets
Sep 3
1/Does the work up for dizziness make your head spin?

Wondering what to look for on an MR for dizziness

This month’s @theAJNR SCANtastic will tell you all you need about imaging Meniere’s disease!

ajnr.org/content/46/8/1…Image
@TheAJNR 2/The etiology for dizziness can have very diverse causes—each with very different treatments.

So it is important to try to differentiate

Meniere’s is a common cause & we can help diagnose it w/imaging! Image
@TheAJNR 3/To understand Meniere’s disease, you must know labyrinth anatomy

It has layers, like Russian nesting dolls. Outer doll is the bony labyrinth, holding perilymph & a second doll—membranous labyrinth.

Inside the membranous labyrinth is endolymph Image
Read 13 tweets
Aug 1
1/They say form follows function!

Brain MRI anatomy is best understood in terms of both form & function.

Here’s a short thread to help you to remember important functional brain anatomy--so you truly can clinically correlate! Image
2/Let’s start at the top. At the vertex is the superior frontal gyrus. This is easy to remember, bc it’s at the top—and being at the top is superior. It’s like the superior king at the top of the vertex. Image
3/It is also easy to recognize on imaging. It looks like a big thumb pointing straight up out of the brain. I always look for that thumbs up when I am looking for the superior frontal gyrus (SFG) Image
Read 12 tweets

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