Lea Alhilali, MD Profile picture
Feb 13, 2023 12 tweets 6 min read Read on X
1/Do you know all the aspects of, well, ASPECTS?

Many know the anterior circulation #stroke scoring system—but posterior circulation (pc) ASPECTS is often unknown

Here’s a #tweetorial to help you remember pc-ASPECTS
#medtwitter #neurotwitter #meded #neurorad #neurology #FOAMed Image
2/Many know anterior circulation ASPECTS. It uses a 10 point scoring system to semi-quantitate the amount of the MCA territory infarcted on non-contrast head CT.

If you need a review: here’s my tweetorial on ASPECTS: Image
3/But it’s only useful for the anterior circulation. Posterior circulation accounts for ~25% of infarcts. Even w/recanalization, many of these pts do poorly bc of the extent of already infarcted tissue. So there’s a need to quantitate the amount of infarcted tissue in these pts Image
4/Posterior circulation ASPECTS, or pc-ASPECTS for short, is also a 10 point system—but for the vertebrobasilar circulation. Patients get points for each region NOT infarcted on the initial CT. Image
5/Similar to anterior ASPECTS, points are GOOD

It’s like a city—when a region infarcts, it is like the lights go out in that city region (literally, tissue darkens on CT)

In ant & post ASPECTS, you are counting the regions where the lights are still on—so high ASPECTS is good Image
6/Which regions get scored?

The biggest prognostic factors in posterior strokes are time & amount of already infarcted tissue.

So my mnemonic to remember pc-ASPECTS regions is:

Time & Mortal Brain decide Posterior Circulation Outcomes
(mortal brain= infarcted brain) Image
7/How do you assign points?

It’s a little different than anterior ASPECTS, where every region just got one point

For pc-ASPECTS, think of it like a mother. She only has 2 arms. So if there are two kids, they have to split the arms—only one arm can be wrapped around each kid Image
8/So unpaired structures, like the brainstem, are like having only one kid—you get both arms wrapped around you = 2 arms = 2 points.

If the structures are paired, like the cerebellum, it’s like having two kids--they must split the arms. Each gets only 1 arm = 1 point Image
9/So lets go through our regions using the mnemonic.

Each thalmus is worth only 1 point, bc they’re paired & have to share their mother’s arms.

The unpaired midbrain is worth 2 points (gets both arms) Image
10/Pons is unpaired, so it is worth 2 points.

But the paired cerebellar hemispheres & occipital cortex are each only worth 1 point per side, as each side claims only one of the mother’s arms Image
11/While there’s evidence that higher pc-ASPECTS means poorer outcome, there’s no consensus about what pc-ASPECTS score definitively confers a UFO (unfavorable outcome).

But the consensus about what confers a UFO in anterior circulation ASPECTS may change soon as well! Image
12/So now you know the regions & scoring for pc-ASPECTS!

Remember, the anterior circulation isn’t the only aspect of ASPECTS! Image

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More from @teachplaygrub

Apr 25
1/Have some confusion about tumor perfusion?

Do you go into a coma looking at scans for glioma?

Never fear!

Read on for this month's @theAJNR SCANtastic for what you need to know on the latest in brain tumor imaging!

ajnr.org/content/45/4/4…
Image
@TheAJNR 2/Since the prehistoric days of medicine (1979!), we knew that some brain tumor patients treated w/radiation (XRT) initially declined, but then get better.

Today, we see this on imaging, where it looks worse early, but then gets better.

Now we call this pseudoprogression. Image
@TheAJNR 3/Why does this happen?

XRT induces a lot of inflammatory changes—from initiating the complement cascade to opening the blood brain barrier (BBB)

It’s these inflammatory changes that make the imaging look worse. Image
Read 21 tweets
Apr 19
1/Having trouble remembering how to differentiate dementias on imaging?

Is looking at dementia PET scans one of your PET peeves?

Here’s a thread to show you how to remember the imaging findings in dementia & never forget! Image
2/The most common functional imaging used in dementia is FDG PET. And the most common dementia is Alzheimer’s disease (AD).

On PET, AD demonstrates a typical Nike swoosh pattern—with decreased metabolism in the parietal & temporal regions Image
3/The swoosh rapidly tapers anteriorly—& so does hypometabolism in AD in the temporal lobe. It usually spares the anterior temporal poles.

So in AD look for a rapidly tapering Nike swoosh, w/hypometabolism in the parietal/temporal regions—sparing the anterior temporal pole Image
Read 16 tweets
Apr 18
1/”That’s a ninja turtle looking at me!” I exclaimed.

My fellow rolled his eyes, “Why do I feel I’m going to see this on X or twitter soon…”

He was right!

A thread about one of my favorite imaging findings & pathology behind it ! Image
2/Now the ninja turtle isn’t an actual sign—yet!

But I am hoping to make it go viral as one.

To understand what this ninja turtle is, you first have to know the anatomy in this region.

I have always thought the medulla looks like a 3 leaf clover in this region. Image
3/ The most medial bump of the clover is the medullary pyramid (motor fibers).

Next to it is the inferior olivary nucleus (ION), & finally, the last largest leaf is the inferior cerebellar peduncle.

Now you can see that the ninja turtle eyes correspond to the ION. Image
Read 11 tweets
Apr 17
1/CSF leaks are controversial!

Some say they're overdiagnosed, others underdiagnosed

How can YOU make sure you aren’t under or overdiagnosing?

Are you BERN-ing to know when to suspect CSF leak?

Here’s a 🧵about the CSF leak Bern score so you don’t get BERN-ed by CSF leaks Image
2/In CSF leaks, everyone knows about brain sagging.

But this can happen w/other diseases, ie Chiari 1.

Other findings can be seen on brain MRI in CSF leaks.

But what are these findings & are some findings more suggestive than others?

Do⬆️findings = ⬆️suspicion? Image
3/The Bern group looked at 9 quantitative & 7 qualitative signs seen on brain MRI in CSF leaks to see which are most important.

Depending on type & # of findings, they developed a score to indicate what level of suspicion you should have for a leak. Image
Read 15 tweets
Apr 15
1/Is remembering cerebellar anatomy making you dizzy?

Need help telling your flocculus from your nodule?

How much cerebellar anatomy do YOU know?

Here’s some help w/an anatomy thread on the 9 lobules of the vermis! Image
2/Coming from anterior, the first lobule is the lingula

It sticks out from the front of the vermis & is connected to the superior cerebellar peduncle (SCP)

I remember this bc of its very appropriate name—lingula—it looks like a tongue sticking out of the vermis to lick the SCP Image
3/Moving clockwise, next is the central lobule

I remember this bc it's positioned exactly how a central lobule should be positioned, in the driver’s seat!

It's where the front driver position would be if the vermis was a car—up front, looking out a windshield over the lingula Image
Read 12 tweets
Apr 12
1/Time is brain! But what time is it?

If you don’t know the time of stroke onset, are you able to deduce it from imaging?

Here’s a thread to help you date a stroke on MRI! Image
2/In ~25% of acute stroke patients, the time of last known well is well, not known.

Then it’s important to use the stroke’s MR imaging features to help date its timing.

Is it hyperacute? Acute? Subacute? Or are the “stroke” symptoms from a seizure from their chronic infarct? Image
3/Strokes evolve, or grow old, the same way people evolve or grow old.

Appearance of stroke on imaging mirrors the life stages of a person—you just have to change days for a stroke into years for a person.

So 15 day old stroke has features of a 15 year old person, etc. Image
Read 22 tweets

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