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Feb 22, 2023 20 tweets 12 min read Read on X
A #CROI2023 special session on #mpox. Some live tweets: Image
Dr. John Brooks, an internist at CDC office of prevention, speaks about #mpox. He notes that we've seen declines worldwide in new cases. 2/ Image
Mpox likely transmitted most via contact with skin and the anorectal area. #CROI2023 3/ Image
Dr. Brooks says, "We don't really know" why #mpox has declined so dramatically. He speculates vaccination and sexual behavior change in gay and bi men likely contributed. He does not mention my theory that the virus ran out of people with high frequency of new partners to infect. Image
Dr. Brooks calls for completion of the clinical trial of antiviral TPOXX , something that is difficult without many cases of #mpox occurring. He says people need to get vaccinated against mpox now before Pride season returns. #CROI2023 Image
Dr. Brooks notes that presymptomatic transmission of #mpox is possible. #CROI2023 Image
Dr. Sharon Frey, Clinical Director, Center for Vaccine Development, St. Louis University: MOLECULAR PATHOGENESIS AND THERAPEUTIC TARGETS FOR MPOX VIRUS lecture
Jynneos has been vaccinated intradermally: Image
Dr. Frey compares smallpox and #mpox at #CROI2023. "The presentation of mpox when it is sexually transmitted is very different from what we know of mpox in the past." Image
Dr. Frey reviews the history of smallpox vaccination. #CROI2023 Image
Post-9/11, Iraq war era, Bush's administration was afraid that Iraq would use biological warfare. It turns out Iraq did not have smallpox on hand. Regardless, a program began to develop a new vaccine for smallpox. #CROI2023 Image
The history of #mpox. #CROI2023
Dr. Frey says that quote about the virus disappearing because of ecological changes has the matter backward. Image
The 21st century #mpox outbreaks.
#CROI2023 Image
A play-by-play of the 2022 #mpox outbreak. Note that researchers later realized there had been signs of the virus in the UK by early April. #CROI2023 Image
The CDC's John Brooks says that there are an est 2M Americans who would be good candidates for #mpox vaccination, because they are a man who has sex with men at risk of sexual acquisition and/or a person with HIV. 1.2M doses have been given; only 470,000 people have both doses.
A PhD student from @fredhutch says there has been "historical revisionism" going on in the talks in today's session. Yes, he says, there was decrease in sexual activity. "I think the LGBTQ community felt very let down by the public health infrastructure."
The @fredhutch student says, "We kind of had to take care of ourselves." He refers to the delay in the vaccine arriving on US shores. "I don't mean to tell you that this is bad or anything, but I don't necessarily think this is as rosy as being presented." (Applause)
"Now is the time to protect yourself. Prepare to be protected so you can take care of yourself in the future," said Dr. John Brooks of CDC at #CROI2023, anticipating that #mpox might rise again with the arrival of #LGBTQ Pride season. Will we see another mpox summer? Image
@MegDoherty_HIV of @WHO in Geneva says there's no guarantee that the public health emergency of international concern regarding #mpox will continue. She asks about the best way to continue monitoring and surveillance and not to lose momentum in combatting the virus. #CROI2023
Dr. John Brooks says, "We have the tools that work, how do we make sure we have equitable access to those around the world." The problem of #mpox, he says at #CROI2023, is growing in W and Central Africa.

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More from @benryanwriter

Mar 24
100s of NIH research grants have been summarily canceled over the past couple of weeks, on the grounds that they support DEI, trans issues, or are at Columbia. Now Trump is targeting mRNA studies, which scientists tell me could jeopardize research into new cancer treatments, for one, as well as the quest for and HIV vaccine. Many of these grants have nothing to do with DEI per se or are particularly focused on transgender people in particular. They seem to have been flagged simply because they have key words that have drawn the attention, and ire, of DOGE. I only have second-hand reports of what DOGE has been doing inside of the NIH and the NIAID.
Today, a titan of biomedical research called me and was reduced to pleading over and over, “Why are they doing this?” as he watched in fear that his life’s work would be destroyed by the Trump administration.
I spoke with one prominent epidemiologist who said that their skills would not be of use outside of academia and that they’d discussed having to move to some cheap place in the country to be able to survive financially.
Read 5 tweets
Mar 12
LEAKED: Trans-Care Training Videos By Beleaguered Top Gender-Clinic Doctor, Part 1

I have obtained 12 hours of videos of top pediatric-gender-clinic physician Dr. Johanna Olson-Kennedy and her colleagues, including her husband, providing training to mental-health providers on how to treat minors who have gender dysphoria or otherwise identify as transgender or nonbinary.

This is the first of 12 installments I will post during the coming weeks of these videos. Subscribe to my newsletter (link in bio) to receive all of them as I publish them.

A 19-year veteran of the pediatric gender medicine field and one of its leading physician-researchers and advocates, Dr. Olson-Kennedy is the medical director of the gender clinic at Children’s Hospital Los Angeles. According to figures she provided during this particular video, annual referrals to her clinic surged from just 25 in 2010 to 436 in 2022—following a similar pattern seen in clinics throughout the Western world.

The past six months have been challenging for Dr. Olson-Kennedy, to say the least.

Dr. Olson-Kennedy is the principal investigator on a National Institutes of Health grant for a long-running research project concerning pediatric gender-transition treatment, one that has received over $10 million to date. In October, The New York Times reported that she has withheld null findings from a study of puberty blockers funded by this grant, doing so for political reasons. The grant is now the subject of a probe by congressional Republicans. In November, however, she asserted in a sworn deposition in a civil case that the Times had mischaracterized her words.

In December, Dr. Olson-Kennedy was sued by a former patient, Clementine Breen, who reported that the gender doctor prescribed her puberty blockers at age 12—on her first appointment, without a psychological assessment—and testosterone at age 13, and then referred her to receive a double mastectomy at age 14. Ms. Breen, now 20, has since detransitioned, reverting to presenting and identifying as a woman.

The Trump administration has unleashed an onslaught against the field of pediatric gender medicine, seeking to wipe it off the map. In recent weeks, the NIH has been canceling research grants related to transgender people, including those conducted with animal models. There is currently a preliminary injunction in place to block the president’s executive order that would freeze federal funds to hospitals that provide gender-transition interventions to those under age 19. Prior to the injunction, Dr. Olson-Kennedy’s clinic had “paused” new cross-sex hormone treatments for youth, only to lift the pause a couple of weeks later.

It remains unclear whether the grant for which Dr. Olson-Kennedy is the top investigator has been canceled. But it is no longer listed on the NIH site where active grants are described.

I reached out to Dr. Olson-Kennedy and her co-principal investigators on the grant to ask about its status. I did not hear back.

Prior to the October Times article, Dr. Olson-Kennedy was perhaps best known by the general public for a previous leaked video in which she was giving a training in 2018 to mental health care providers on how to write referral letters for minors seeking gender-transition surgeries. In the video, she expresses exasperation with what she sees as hand wringing over whether natal girls will later regret having their breast removed during adolescence. (At least 1,000 such surgeries have been conducted annually in recent years.)

She says: “What we do know is that adolescents actually have the capacity to make a reasonable, logical decision. And here’s the other thing about chest surgery. If you want breasts at a later point in your life, you can go and get them!”

Ms. Breen recently reported that she was undergoing reconstructive surgery to provide herself with new breasts. However, it is very unlikely she will ever be able to breastfeed should she have children.

Dr. Olson-Kennedy is also newly the president of USPATH, the U.S. branch of the medical-activist group the World Professional Association for Transgender Health. WPATH, which despite is name is largely a U.S.-based organization, has been besieged by damaging publicity over the past year, in particular after internal documents subpoenaed by Alabama’s attorney general revealed that its leadership was aware that the evidence behind pediatric gender medicine was weak and sought to paper over this fact.

12 hours of leaked Olson-Kennedy training videos

The 12-hour training in what is known as the gender-affirming care method for minors who identify as trans or nonbinary took place in late April 2024—a few weeks after Britain published the Cass Review, which found that this medical field is based on “remarkably weak evidence.” The training was led by Dr. Olson-Kennedy; her husband, Aydin Olson-Kennedy, who has a doctorate in social work and is a transgender man; and licensed clinical social worker Darlene Tando.

I obtained the videos a few months ago.

The training videos are a window into not just the methods of these individuals, but their overall attitudes about gender dysphoria and transgender and nonbinary identification in children. A prevailing attitude they share is one of indignation and irritation with a medical system that demands that children betray a substantial level of distress before they are granted gender-transition medications. Overall, these three favor less gatekeeping and less pathologizing of the mental states and internal lives of the children in their care. If a gender-incongruent child arrives in their care absent any particular distress about their identification as the opposite sex, they believe that that child should be granted the opportunity to medically transition by taking puberty blockers and cross-sex hormones if the family wishes.

I have edited the videos to snip or crop out images that would identify the participants in the training, whether because of Zoom-chat questions that pop up in the right-hand corner of the screen, or moments when a matrix of the participants is visible. You can watch the video at the beginning of this Substack. Otherwise, I wrote a summary below:
LINK:
LEAKED: Trans-Care Training Videos By Beleaguered Top Gender-Clinic Doctor, Part 1
benryan.substack.com/p/leaked-trans…
I am publishing 12 hours of videos of Dr. Johanna Olson-Kennedy and colleagues in which they train mental-health providers on treating children who have gender dysphoria or otherwise identify as trans.

Subscribe to my newsletter to receive all the videos as I publish them.Image
Video number 1: Johanna Olson-Kennedy on the gender basics
benryan.substack.com/p/leaked-trans…
Dr. Olson-Kennedy opens the video by charting the recent shift in transgender visibility in popular media, which she says has improved dramatically in recent years. Previously, transgender people were frequently presented as sex workers, according to at GLAAD analysis. But these days, TV has benefited from the likes of Jazz Jennings and shows like Transparent and Pose that center on the transgender experience, Dr. Olson-Kennedy says. Having stories about youth in the media in particular, she says, has influenced the seeking of gender-transition treatment by young people.

She expresses concern that the trans kids whose stories have been told in the media are generally white. This is reflective, she says, of the disproportionately white patient population at gender clinics in the U.S. and Europe. “It is important for all of us to think about what those barriers to care are for other communities and work really hard to dismantle those barriers.”

This remark speaks to a common dichotomy among advocates in this medical field: They will at once characterize the number of children receiving these treatments as low (as Dr. Olson-Kennedy does a bit later in the video), emphasizing that the political firestorm over this population is disproportionate to its size, while also decrying how few kids are receiving the treatment.

Since 2021, Dr. Olson-Kennedy says, we’ve seen a “problematic” visibility of trans youth as states have moved to ban these treatments. She shows a Google search she conducted of “transgender youth care” the night before. “All of these six headlines, and there’s many more,” she says, “are negative, and they speak to moves being made to ban access to care.”Image
Read 20 tweets
Mar 9
Research indicates that even after undergoing lengthy testosterone suppression and estrogen treatment, natal males who identify as female hold a competitive advantage in women’s sports. This is not just about height. It’s about muscle strength, shoulder and hand size, oxygen processing, etc.

And there are teenage boys who can bear Katie Ledecky, one of the most unbeatable long-distance swimmers in history.Image
*beat Katie
Read 4 tweets
Mar 7
The difference between the trans sports question and past battles over interracial and same-sex marriage is that there was never any rational scientific support for opposition to those rights. But research does indicate that trans women maintain a competitive advantage in women’s sports. @mattyglesias @drvoltsImage
So is it “morally repugnant” as @drvolts claims, for @mattyglesias to back trans-girl exclusion from girls’ sports if their inclusion is unfair to c-s girls, per scientific research? Is inclusion more important than fairness?

I would be very interested to know why David Roberts thinks it is fair to include trans girls and women in girls and women’s sports.
Read 6 tweets
Feb 10
$544,000-a-Year, Newly Nonbinary @ACLU Executive Makes Incorrect Claims About Pediatric Gender Medicine: Will This Impact Landmark Supreme Court Case?

🧵👇I report for the @NewYorkSun: Hired in 2019 as the ACLU’s first DEI chief, AJ Hikes has also emerged at the center of a labor-rights case against the nonprofit that deemed it illegally fired a staffer on unsubstantiated claims of racism.Image
GIFT LINK: $544,000-a-Year, Nonbinary ACLU Executive Makes Incorrect Claims About Pediatric Gender Medicine: Will This Impact Landmark Supreme Court Case?
nysun.com/article/544000…
Hired in 2019 as the ACLU’s first DEI chief, AJ Hikes has also emerged at the center of a labor-rights case against the nonprofit that deemed it illegally fired a staffer on unsubstantiated claims of racism.Image
The @ACLU's 4th highest-paid staffer, AJ Hikes, who was hired in 2019 as its first DEI officer, whose 2023 salary exceeded $540K, and who wields considerable influence as a close advisor to the executive director, has drawn unflattering attention to the storied legal group. Image
Read 20 tweets
Feb 9
How the NIH cuts would decimate pediatrics research at UNC and likely undermine the hospital system:
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Recall how vitally important fertility is to JD Vance in particular. Keeping babies from dying is central to such an aim.
Read 4 tweets

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