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Dr Elisa Perego Profile picture
@elisaperego78
Apr 1 • 8 tweets • 5 min read Twitter logo Read on Twitter
I am retweeting this thread of mine from last year on the so-called "medium covid". We're seeing this concept going around again, trying to minimize #LongCovid. And create confusion. You can be ill from SARS-CoV-2 infection for months, years, a lifetime. Be careful out there
From my last year's thread, actually, more research data have come out, which reinforce our concerns for the prolonged effects of SARS-CoV-2 infection on human health. For example, growing evidence about the association with autoimmune diseases

thelancet.com/journals/eclin…
There is increasing evidence about the effects of SARS-CoV-2 infection on our DNA and gene expression, with potential deleterious, nefarious implications for #LongCovid

nature.com/articles/s4156…

nature.com/articles/s4155…
Data about the increased cardiovascular risk following SARS-CoV-2 infection and in #LongCovid continue to accumulate (including about an increased risk for death, pulmonary embolism or deep vein thrombosis, cardiac arrhythmias, and ischemic stroke)

jamanetwork.com/journals/jama-…
This isn't really a surprise for anyone following the Covid crisis and the research closely: but even the CDC has officially admitted #LongCovid can kill. These data reported officially are likely very underestimated, but it's a start.

cnbc.com/2022/12/14/lon…
The evidence Covid is linked to diabetes, dyslipidaemia and metabolic disorders is growing further and further, including from omicron

thelancet.com/journals/landi…

cidrap.umn.edu/covid-19/covid…

news-medical.net/news/20230108/…
More research is being carried out, with concerning results, about exposure to SARS2 in utero i.e. during pregnancy, and negative effects on the newborn, like in this study on neurodevelopmental disorders (still have to read the study, but news attached)

hms.harvard.edu/news/utero-sar…
And, of course, new on #longSARS: some fresh, long-term data on a group of survivors from the first SARS. The study, in the Lancet just one month ago, showed many patients weren't fully recovered even after 18 years (small sample but important)

thelancet.com/journals/eclin…

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More from @elisaperego78

Dr Elisa Perego Profile picture
Apr 2
A kind reminder many survivors of the first SARS were ill for years and at least some (where analysis is done or first-hand testimonials are available) never recovered. I don't know how people can think mass infection with SARS-CoV-2 is ok, including for children

#longSARS
About the latest research on the long-term damage from SARS (#longSARS) this from just one month ago

thelancet.com/journals/eclin…
But it was already known before the current pandemic: SARS left many people who survived the acute phase of the disease with prolonged ill health, prolonged disease. A thread of mine on the topic from 2021, where you can find more sources

Read 4 tweets
Dr Elisa Perego Profile picture
Mar 22
“Long Covid as a multi-system disease: What the research tells us?”
My new blog on #LongCovid is out. Thanks @alitwy for the kind invitation to contribute to her project (which hosts my piece)
allaboutlongcovid.uk/2023/03/22/lon… via @alitwy
In my piece, I explore some mechanisms involved in the long-term manifestations of SARS-CoV-2 infection–Covid (#LongCovid), including potential risks associated with reinfections and lack of appropriate clinical evaluation for patients.
“#LongCovid is a multi-system, heterogeneous disease. As a disease entity, Long Covid can basically affect all systems and organs in the body.

sciencedirect.com/science/articl…
Read 35 tweets
Dr Elisa Perego Profile picture
Mar 22
Controlling the flow of information is a way of controlling people. Nothing knew. But we're now in one of the major, global health disasters in recent history: the Covid pandemic. Please keep yourself informed on Covid, Long Covid, and how SARS-CoV-2 spreads. Knowledge is power
This pandemic has been rife with misinformation, including by major actors in policymaking. Do you remember when we were told that Covid lasted on average two weeks, children didn't get sick, SARS-CoV-2 wasn't airborne, and the pandemic was going to end, like, ages ago?
Yet, we know SARS-CoV-2 can spread and linger in the air, a bit like cigarette smoke. We know Covid is "long", and comes with prolonged disease and delayed complications from infection (#LongCovid). We know the pandemic is still very much here. We know children can get very ill.
Read 4 tweets
Dr Elisa Perego Profile picture
Mar 21
"I hope to be able to play again"

Sport star Brandon Sutter, 34, opens up about his ongoing battle with #LongCovid, and recent improvements which could lead to a return to sport. Brandon got Covid in March 2021 and his career has been in jeopardy since

sportsnet.ca/nhl/article/af…
In 2022 Sutter said “Basically, I’ve been left with a lot of different things. With my lungs and my breathing and any exertion, I just can’t do it. I stop and feel like I have to cough something out and just feel like I can’t get oxygen into my body.
I still can’t do any cardio. I tried working out again in March and April [2022] to kind of get going again. But I’d have a really bad day and it would just crush me —
Read 8 tweets
Dr Elisa Perego Profile picture
Mar 20
Yes, #LongCovid comes with organ damage, coagulation abnormalities, cardiovascular disease, and many other conditions affected basically all body systems. This is scientifically proven by a significant amount of both biomedical papers and patient-driven data collection
Yes, #LongCovid isn't rare. It has been called a "mass disabling event", the effects of which we're fully starting to see on our economy and healthcare systems e.g.

cnbc.com/2023/01/30/lon…
Yes, #LongCovid, Long Haul Covid and long haulers are terms/ concepts created within the community of Covid survivors, who were the first to document, research, describe the disease. This patient-driven, collective effort has been a turning point in medical and pandemic history
Read 7 tweets
Dr Elisa Perego Profile picture
Mar 17
Thanks to Italy's press agency of pharmacists for publishing the research and advocacy note @MartaEsperti (@longcoviditalia) and I wrote on #LongCovid in occasion of #LongCovidAwarenessDay

rifday.it/2023/03/16/gio…
We underlined 15 March has been chosen by patients for patients to advocate for #LongCovidAwareness. We remembered Long Covid has been a term and a concept defined by patients from early 2020. We remembered the WHO recognized Long Covid in August 2020, and Italy in 2021
We underlined we have now a lot of scientific data on acute and #LongCovid (see PubMed). We noted Covid and Long Covid can basically hit all organs and body systems. We underlined the relapsing-remitting, sometimes progressive, and at times subclinical pathology in Long Covid
Read 6 tweets

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