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Anybody who is paying even the slightest attention knows that ketogenic diets (KD) can have positive effects on neurodegenerative diseases and mental disorders. (1/7)
The beneficial effects in treating mood disorders are thought to involve the alleviation of neuroinflammation, hippocampal neurogenesis, neuroendocrine regulation, and gut microbiota composition. (2/7)
On a molecular level, the cornerstone of these effects is improved energy metabolism resulting in reduced production of free radicals and cell death. This, in turn, is thought to have a positive impact on the body's inflammation levels. (3/7)
Although there have been no RCTs proving the efficacy of Ketogenic Diets in Major Depressive Disorder and Bipolar patients, there is some pretty impressive data about to drop in the form of a single-arm clinical trial for MDD and ongoing RCT for Schizophrenia (4/7) #StayTuned
Potential underlying mechanisms of the antidepressant effect of KD have been investigated in several preclinical studies. (5/7)
We do have published case reports in peer-reviewed journals. And a resounding crowd of people benefitting and sharing their stories of feeling exponentially better on a ketogenic diet. (6/7)
If you have such a story to share, go ahead and do so in the comments. It will be my joy to celebrate with you and retweet it! (7/7)
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