Paul Saladino, MD Profile picture
Apr 5, 2023 8 tweets 3 min read Read on X
5 foods you think are healthy that are NOT:

1. Oatmeal
2. Peanut butter
3. Spinach
4. Chia seeds
5. Almond milk Image
Oatmeal:

-Oats contain significant amounts of phytic acid, a molecule that chelates minerals and prevents their absorption.

-Most of this phytic acid survives cooking (though fermentation can degrade phytic acid).

tldr: oatmeal robs you of minerals Image
Peanut butter:

-Major source of aflatoxin (well known carcinogen) from mold on peanuts.

-Peanut lectin is known to enter the blood stream, where it can act as a possible immune trigger...

-Peanut oil (seed oil) is ~ 30% linoleic acid = high levels of oxidation on shelves. Image
Spinach:

- Huge source of oxalates (545mg per 100g), known contributors to the most common type of kidney stones (calcium oxalate).

-Oxalate is not degraded by cooking Image
Chia seeds:

- Very poorly digestible by humans. Documented cases of bowel/esophageal obstruction.

- That "fun" gelatinous coating around them prevents their digestion... Image
Almond "Milk:"

- Many contain seed oils (canola, safflower etc.) and/or carrageenan (sulfated polysaccharide from algae implicated in gut irritation/inflammation).

- Phytic acid (as above).

- Oxalates (as above). Image
Getting rid of these 5 "healthy" foods could significantly IMPROVE your health!
What should you eat?

Think for yourself and be curious, but I'd recommend meat and organs as the center of your diet with some fruit/honey for carbohydrates. #animalbased

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More from @paulsaladinomd

Sep 15
Taurine is the next creatine.

Hear me out...

RCTs in humans show clear benefits from taurine (1-6g per day) in both disease states and for exercise performance.

Taurine is powerful stuff. 🧵 Image
Blood pressure reduction (PMID: 26781281), both SBP (systolic) and DBP (diastolic)

Improved vascular function in Type 2 DM (40546935)

Improved markers of metabolic syndrome including SBP/DBP, decreased triglycerides, decreased fasting glucose (38755142)
Decreased HgbA1c, fasting glucose, HOMA-IR, fasting insulin in type II DM and obesity cohorts (35769396, 39796489)
Read 16 tweets
Sep 15
Biggest nutrient deficiency in the US?

Potassium? Choline? Vitamin D?

Nope, it’s infrared light (760-1000nm). 🧵 Image
Believe it or not, the mitochondria in every cell in your body make the MAJORITY of your melatonin. (>95%) in response to infrared light (PMID 36671781, 29164625)

And almost NONE of us are getting enough of it.
We spend >97% of our lives indoors, where there is very little IR light.

If you live 86 years, you will spend 83 of them indoors.

Most of us spend less than 30 minutes per day truly outside. No bueno.
Read 8 tweets
Apr 2
I am not a fan of methylene blue. The data clearly shows that unless you have a block in your electron transport chain, it LOWERS ATP production in your mitochondria.

I think most people are conflating MAO-A inhibition and serotonergic effects with mitochondrial benefit.
Yes, metabolic dysfunction is common but methylene blue is not the way to address this.

The easy root cause solution is to cut out seed oils and processed sugars rather than turning your tongue (and brain) blue.
PMID: 21454572, 25277417, 35777722
Read 4 tweets
Mar 9
Sugar is bad for you, but not for the reason you think.

Sugar is NOT bad for you because it raises your blood sugar.

Sugar is bad for you because it causes dysbiosis in your gut => increases endotoxin =>inflammation/metabolic dysfunction.

A thread... 🧵 Image
From the outset, it's important to point out that "naked sugar" (think table sugar= sucrose and high fructose corn syrup) has different effects in the body than sugar consumed as a part of fruits/fruit juice/honey etc.. we'll get to this eventually...
Most believe that "naked sugar" is bad for you because if raises your blood glucose, but there is a dearth of evidence to actually suggest that raising your blood sugar is harmful for humans at all independent of pre-existing diabetes (PMID: 30249012). Image
Read 25 tweets
Jan 1
Fasting insulin is a SINGLE, CHEAP, EASY BLOOD TEST that could change the health landscape in the United States over night. Image
If every doctor ordered a fasting insulin ($30) on their patients -and knew how to interpret it**- we would immediately understand how great the burden of metabolic dysfunction in our country is and we could begin targeting it effectively.
The problem here is doctors are NOT taught that:

a) metabolic dysfunction (aka insulin resistance) lies at the root of the MAJORITY of chronic illness in our country...

b) metabolic dysfunction is EASILY diagnosable...

c) metabolic dysfunction is EASILY reversible.
Read 16 tweets
Aug 25, 2024
Seed oils ARE inflammatory. Full stop.

They increase oxidized LDL (PMIDs: 2008870, 14739118, 8432867, 28503188, 9488997).

Oxidized LDL is known to worsen atherosclerosis (PMID 24222937) and to bind C-reactive protein (CRP) (12244213) a marker of inflammation.

(All studies cited are in humans)

1/8Image
Seed oils increase Lp(a) (PMIDs: 21466598, 14739118).

Lp(a) is known to be pro-atherogenic, pro-thrombotic and pro-inflammatory (32453609)

2/8
Seed oils increase Lp-PLA2 (Lipoprotein-associated phosholipase A2) (PMID: 28503188).

Increased LP-PLA2 is strongly associated with increased cardiovascular disease (PMIDs: 22499993, 17431184) and cleaves oxidized phospholipids in LDL.

3/8
Read 8 tweets

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