Ten current papers for the curious cardiologist - 2023 week 40 - including CTCA in type 2 MI, peripartum cardiomyopathy outcomes, IE prophylaxis and enteric-coated Vs uncoated aspirin.
1) CTCA with FFR in 50 pts with type 2 MI showed 92% had CAD, and 26% had obstructive disease, supporting use of aspirin and lipid lowering therapy in pts with T2MI.
Ten current papers for the curious cardiologist, including transcatheter valve in the mitral position, NTproBNP in a healthy population, impact of diagnosing type 2 MI and effect of smoking cessation post PCI.
Ten current papers for the curious cardiologist, including mitraclip in secondary MR, possible cause of AVB in young pts, use of calcium score from non-gated chest CT to risk stratify pts pre non-cardiac surgery and HF pts and pregnancy.
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1) Use of MitraClip in pts with secondary MR – COAPT-PAS, US prospective observational study of 5000 pts, showed significantly⬇️mortality & HF hospitalisation compared to pts in COAPT-RCT GDMT arm ( 33.7% Vs 46.2%)
2) High Hs-cTnT post cardiac surgery is associated with ⬆️ 30d mortality but not 5yr. Thresholds defining mortality-associated postoperative myocardial injury were 170xURL for CABG (resulting in a 30d HR of 12.6) and 41xURL for AVR (30d HR of 4.4)
Ten current papers for the curious general cardiologist, including ticagrelor monotherapy post PCI, MRA use in cardiac amyloid, asystole post shock from wearable defibs & ⬇️in mortality using telemonitoring in HF
1) At 3 months post PCI, the TWILIGHT RCT published in @JACCJournals showed ticagrelor monotherapy compared to continued DAPT (ticagrelor and aspirin) resulted in lower bleeding risk with no increase in ischaemic risk
2) The MACT proof of concept pilot trial (200pts) showed in ACS pts undergoing PCI it was feasible to discontinue aspirin the day after PCI & continue ticagrelor or prasugrel antiplatelet monotherapy combined with low-dose colchicine.
Ten current papers for the curious general cardiologist, including troponin in stable CAD, coronary assessment in VT storm, balloon pulmonary angioplasty and CIED infections
1) Use of hs-cTnI to risk stratify pts with chronic CAD: 1 in 25 had trop >99th percentile & these pts had a 4x ⬆️risk MI/CV death vs pts <5ng/L. -MICA study in @JACCJournals
1) Should we use the highest beat/signal in AF? Slide shown by Sanjeev Bhattacharyya
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2) Peripartum cardiomyopathy - don't miss it and remember need to counsel/risk stratisfy if considering future pregnancies. Slide shown by @BSE_President Claire Colebourn at #BSEcho2022
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3) The adult ACHD population is larger than the paediatric one, and 86% have biventricular anatomies. Interesting UK data shown by Liam Corbett at #BSEcho2022