Maryanne Demasi, PhD Profile picture
May 5, 2023 8 tweets 6 min read Read on X
🧵 Thread on my statin research 👇🏼

Our analysis in @JAMAInternalMed
21 statin trials, 143,532 participants

The benefits of #statins were minimal & most trial participants who took statins, derived no clinical benefit.

Reducing LDL-C with statins showed an inconsistent/weak… twitter.com/i/web/status/1… Image
We respond to a critique by @PeterAttiaMD of our systematic review and meta analysis of #statin trials

tinyurl.com/rssdns32 Image
Proposed guidelines in the UK recommend #statins to all adults if “the person is happy to take a statin”.

Here’s why it’s a bad idea 👇🏼
tinyurl.com/254987zj Image
Do statins cause muscle aches?
~ 50% of patients stop their statins within 1yr of commencing therapy, mostly because of muscle problems.

But a major study published in @TheLancet concluded that statins are rarely to blame.

See why I disagree tinyurl.com/2n69678u Image
Experts proposed that #statins should be available over the counter.

Cardiologist Robert DuBroff and I disagree. 👇🏼

tinyurl.com/54cbymh9 Image
Here is a documentary I produced about cholesterol, statins and heart disease, which led to powerful vested interests calling for its censorship. Featuring @RFRedberg @DrJohnAbramson & more

tinyurl.com/caz2yyav Image
Scientific Censorship - read what led to the unravelling of scientific journalism at ABC TV and the prolonged, orchestrated attacks on those challenging orthodoxy.

tinyurl.com/26sc7nz9 Image
STATIN WARS: have we been misled by the evidence? Published in 2018 by BMJ’s BJSM. @BJSM_BMJ

bjsm.bmj.com/content/bjspor… Image

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More from @MaryanneDemasi

Aug 12
❌RETRACTED: How a peer-reviewed study was killed by a “fact check”
When a medical journal starts outsourcing its editorial judgement to media fact-checkers, the entire premise of peer review collapses.

LINK below 👇👇
@newstart_2024 @Jikkyleaks @Kevin_McKernanImage
In April 2024, a peer-reviewed study by Japanese researchers was published in @CureusMedical.

The study, led by Dr Miki Gibo, a primary care physician at the Matsubara Clinic in Kochi, Japan, found that in 2022 there was a statistically significant rise in deaths from certain cancers coinciding with the rollout of Covid-19 mRNA injections.

They made no claim of causation — only correlations — and outlined several possible explanations, including Covid-19 vaccination, lockdowns, and reduced cancer care.Image
By June, the study had been retracted--not because of a scientific rebuttal but by a @Reuters “fact check.”

In an internal email dated June 12, 2024, Cureus Director of Publishing Graham Parker-Finger wrote to the study authors:

“Reuters published a fact check of this article that details several concerns regarding the contents. As a result, Cureus plans to conduct a detailed post-publication editorial review to examine these concerns…”Image
Read 5 tweets
Aug 5
🔥EXCLUSIVE: Whistleblower says Merck ignored evidence linking Gardasil to autoimmune disease

New court filings reveal a clinical trial investigator tried to warn Merck of autoimmune injuries from Gardasil—but says the company shut him down.

LINK 👇👇
@Jikkyleaks @DrPatSoonShiong @WisnerBaum
@MdBreathe @newstart_2024 @TheChiefNerdImage
Dr Jesper Mehlsen, a Danish physician and former Merck trial investigator, alerted the company to signs of autonomic dysfunction following vaccination.

According to Mehlsen, those warnings were “discarded.” Image
Mehlsen’s clinic assessed 839 referred patients and conducted a comprehensive investigation, with the findings published in a 2022 peer-reviewed study in the Journal of Autoimmunity.

His conclusion: “Girls and young women with probable side effects to HPV-vaccination have symptoms and biological markers compatible with an autoimmune disease.” sciencedirect.com/science/articl…
Read 5 tweets
Jul 14
🔥Exposing the rot: Journal ignores missing data on Covid vaccine safety in pregnancy

The study authors quietly excluded 22 vaccinated women from their final analysis, and the outcomes of those pregnancies were never disclosed. If included, the data could have dramatically altered the study’s conclusions.

LINK below👇👇
@RetsefL @JikkyleaksImage
The 2022 study was widely used to reassure the public about the safety of Covid-19 vaccination during pregnancy.

It reported no increased risk of stillbirth or preterm birth among women who received Covid-19 mRNA vaccines during pregnancy compared to those who remained unvaccinated--BUT IT EXCLUDED 22 WOMEN WHO'D BEEN VACCINATED.
…pregnancychildbirth.biomedcentral.com/articles/10.11…Image
MIT professor @RetsefL & paediatrician Efrat Schurr published a critique of the study highlighting methodological flaws and asked for the missing data -- but the authors refused to hand it over.
…pregnancychildbirth.biomedcentral.com/articles/10.11…Image
Read 5 tweets
Jul 2
🚨The 'plot' to take down RFK Jr looks familiar
A leaked memo published at @brownstoneinst reveals how powerful pharmaceutical interests are plotting to remove RFK Jr. from office. I’ve seen this playbook before—because a decade ago, they used it on me.

SEE BELOW:👇👇

@jeffreyatucker @lifebiomedguru @Jikkyleaks @newstart_2024
@TheChiefNerd @maryhollandnyc @ProfTimNoakesImage
The document, reportedly from the Biotechnology Innovation Organization (BIO)—the largest pharmaceutical lobby group in the US—outlines a US$2mil campaign to “neutralise” Kennedy before September.
brownstone.org/articles/the-p…Image
The Merck precedent

Back in the early 2000s, pharmaceutical giant Merck faced growing criticism of its blockbuster painkiller, Vioxx.

Internal emails uncovered during litigation revealed that Merck kept a literal “hit list” of doctors and academics who spoke out about the drug’s cardiovascular risks.

“We may need to seek them out and destroy them where they live.”Image
Read 6 tweets
Jun 24
🛑The Cutter Incident - did we learn anything from the Covid vaccine rollout?

The Cutter Incident exposed a critical vulnerability in vaccine production- protocols that are safe & effective in the lab don’t always hold up under the pressures of large-scale manufacturing. 👇👇

@Jikkyleaks @RetsefL @Kevin_McKernanImage
Salk’s inactivated POLIO vaccine was seen as a breakthrough - the US gov rushed to roll it out in 1955.

But in the haste to scale up production, oversight of the manufacturing process slipped.

One manufacturer, Cutter Laboratories, failed to properly inactivate the virus in some of its vaccine batches. The consequences were devastating.

Around 200,000 children received doses that inadvertently contained live poliovirus. More than 200 were paralysed. At least 10 died.Image
The Covid-19 vaccines were developed at ‘warp speed’. Pfizer’s pivotal clinical trial tested a product manufactured using “Process 1” - a tightly controlled, small-scale method suited to producing ‘clean’ batches for clinical trials.

But to meet global demand, Pfizer quietly switched to “Process 2” - a large-scale industrial method using bacteria to amplify plasmid DNA. This change dramatically altered how the product was manufactured.

Put simply, the product tested in the clinical trials on the majority of participants, was fundamentally different from the product that was rolled out to the entire population.

@joshg99 & @RetsefL wrote a letter to the BMJ
bmj.com/content/378/bm…Image
Read 5 tweets
May 7
🚨Merck rigged Gardasil trials to conceal harms, court documents reveal
A forensic analysis by @PGtzsche1 - now part of the official court record—lays bare a chilling narrative of clinical trial rigging, regulatory failure, and global deception.



@DrPatSoonShiong @TheChiefNerd @Jikkyleaks @MdBreathe @Liz_Wheelerblog.maryannedemasi.com/p/merck-rigged…Image
Trials were designed to mislead

From the outset, @PGtzsche1 argues that Merck engineered its clinical trials not to detect harms, but to mask them.

Rather than using an inert placebo—such as saline solution, the gold standard in clinical research—Merck used an aluminium-based adjuvant as the control in all but two small trials.

And those two trials—marked with a red box below—showed a significantly greater incidence of harm compared to trials that used an aluminium adjuvant or a comparator vaccine as the "placebo."Image
Concealing harms by slicing the data

Beyond trial design, @PGtzsche1 details how Merck systematically manipulated the recording and reporting of adverse events.

Participants were monitored for harms for just 14 days following each vaccine dose—a relatively short window.

Autoimmune reactions and other vaccine-related harms can take weeks or months to emerge, and sometimes years to diagnose e.g. POTS

If an adverse event occurred outside this 14-day window, it was not counted as a vaccine-related effect, but reclassified as a “new medical history” and obscuring any connection to the vaccine.

“By calling adverse events ‘new medical history’, Merck not only concealed important adverse events but also their severity,” Gøtzsche explains.Image
Read 5 tweets

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