Maryanne Demasi, PhD Profile picture
May 5, 2023 8 tweets 6 min read Read on X
🧵 Thread on my statin research 👇🏼

Our analysis in @JAMAInternalMed
21 statin trials, 143,532 participants

The benefits of #statins were minimal & most trial participants who took statins, derived no clinical benefit.

Reducing LDL-C with statins showed an inconsistent/weak… twitter.com/i/web/status/1… Image
We respond to a critique by @PeterAttiaMD of our systematic review and meta analysis of #statin trials

tinyurl.com/rssdns32 Image
Proposed guidelines in the UK recommend #statins to all adults if “the person is happy to take a statin”.

Here’s why it’s a bad idea 👇🏼
tinyurl.com/254987zj Image
Do statins cause muscle aches?
~ 50% of patients stop their statins within 1yr of commencing therapy, mostly because of muscle problems.

But a major study published in @TheLancet concluded that statins are rarely to blame.

See why I disagree tinyurl.com/2n69678u Image
Experts proposed that #statins should be available over the counter.

Cardiologist Robert DuBroff and I disagree. 👇🏼

tinyurl.com/54cbymh9 Image
Here is a documentary I produced about cholesterol, statins and heart disease, which led to powerful vested interests calling for its censorship. Featuring @RFRedberg @DrJohnAbramson & more

tinyurl.com/caz2yyav Image
Scientific Censorship - read what led to the unravelling of scientific journalism at ABC TV and the prolonged, orchestrated attacks on those challenging orthodoxy.

tinyurl.com/26sc7nz9 Image
STATIN WARS: have we been misled by the evidence? Published in 2018 by BMJ’s BJSM. @BJSM_BMJ

bjsm.bmj.com/content/bjspor… Image

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More from @MaryanneDemasi

Jul 2
🚨The 'plot' to take down RFK Jr looks familiar
A leaked memo published at @brownstoneinst reveals how powerful pharmaceutical interests are plotting to remove RFK Jr. from office. I’ve seen this playbook before—because a decade ago, they used it on me.

SEE BELOW:👇👇

@jeffreyatucker @lifebiomedguru @Jikkyleaks @newstart_2024
@TheChiefNerd @maryhollandnyc @ProfTimNoakesImage
The document, reportedly from the Biotechnology Innovation Organization (BIO)—the largest pharmaceutical lobby group in the US—outlines a US$2mil campaign to “neutralise” Kennedy before September.
brownstone.org/articles/the-p…Image
The Merck precedent

Back in the early 2000s, pharmaceutical giant Merck faced growing criticism of its blockbuster painkiller, Vioxx.

Internal emails uncovered during litigation revealed that Merck kept a literal “hit list” of doctors and academics who spoke out about the drug’s cardiovascular risks.

“We may need to seek them out and destroy them where they live.”Image
Read 6 tweets
Jun 24
🛑The Cutter Incident - did we learn anything from the Covid vaccine rollout?

The Cutter Incident exposed a critical vulnerability in vaccine production- protocols that are safe & effective in the lab don’t always hold up under the pressures of large-scale manufacturing. 👇👇

@Jikkyleaks @RetsefL @Kevin_McKernanImage
Salk’s inactivated POLIO vaccine was seen as a breakthrough - the US gov rushed to roll it out in 1955.

But in the haste to scale up production, oversight of the manufacturing process slipped.

One manufacturer, Cutter Laboratories, failed to properly inactivate the virus in some of its vaccine batches. The consequences were devastating.

Around 200,000 children received doses that inadvertently contained live poliovirus. More than 200 were paralysed. At least 10 died.Image
The Covid-19 vaccines were developed at ‘warp speed’. Pfizer’s pivotal clinical trial tested a product manufactured using “Process 1” - a tightly controlled, small-scale method suited to producing ‘clean’ batches for clinical trials.

But to meet global demand, Pfizer quietly switched to “Process 2” - a large-scale industrial method using bacteria to amplify plasmid DNA. This change dramatically altered how the product was manufactured.

Put simply, the product tested in the clinical trials on the majority of participants, was fundamentally different from the product that was rolled out to the entire population.

@joshg99 & @RetsefL wrote a letter to the BMJ
bmj.com/content/378/bm…Image
Read 5 tweets
May 7
🚨Merck rigged Gardasil trials to conceal harms, court documents reveal
A forensic analysis by @PGtzsche1 - now part of the official court record—lays bare a chilling narrative of clinical trial rigging, regulatory failure, and global deception.



@DrPatSoonShiong @TheChiefNerd @Jikkyleaks @MdBreathe @Liz_Wheelerblog.maryannedemasi.com/p/merck-rigged…Image
Trials were designed to mislead

From the outset, @PGtzsche1 argues that Merck engineered its clinical trials not to detect harms, but to mask them.

Rather than using an inert placebo—such as saline solution, the gold standard in clinical research—Merck used an aluminium-based adjuvant as the control in all but two small trials.

And those two trials—marked with a red box below—showed a significantly greater incidence of harm compared to trials that used an aluminium adjuvant or a comparator vaccine as the "placebo."Image
Concealing harms by slicing the data

Beyond trial design, @PGtzsche1 details how Merck systematically manipulated the recording and reporting of adverse events.

Participants were monitored for harms for just 14 days following each vaccine dose—a relatively short window.

Autoimmune reactions and other vaccine-related harms can take weeks or months to emerge, and sometimes years to diagnose e.g. POTS

If an adverse event occurred outside this 14-day window, it was not counted as a vaccine-related effect, but reclassified as a “new medical history” and obscuring any connection to the vaccine.

“By calling adverse events ‘new medical history’, Merck not only concealed important adverse events but also their severity,” Gøtzsche explains.Image
Read 5 tweets
Apr 23
💥Slovakia launches Covid-19 vaccine probe after DNA contamination findings

A scientific analysis has sparked calls for transparency, independent testing, and a freeze on future vaccine deliveries to Slovakia.


@Jikkyleaks @Kevin_McKernan @MdBreatheblog.maryannedemasi.com/p/slovakia-lau…Image
The move, announced by Slovakia’s Prime Minister @RobertFicoSVK, follows an independent scientific analysis commissioned abroad by Czech researcher Dr Soňa Peková,

The report found that vaccine samples used in Slovakia, contained "extremely high levels of DNA" that the “manufacturer did not disclose” in the relevant regulatory documents. blog.maryannedemasi.com/p/new-evidence…Image
PM @RobertFicoSVK stated that he would task the Slovak Academy of Sciences—the country’s leading scientific institution—with repeating the analysis as soon as possible.

“In addition to the expert opinion,” he said, “only the Slovak Academy of Sciences and its expert departments can carry out another quantitative analysis of the presence of DNA and other substances in selected samples of vaccines used by the Slovak population.”Image
Read 5 tweets
Apr 15
📢The silencing of scientific curiosity
Medical journals have became enforcers of orthodoxy—retracting genuine hypotheses while protecting proven fraud.

Why is a 'hypothesis' a threat to science?


@SabinehazanMD @Jikkyleaks @Kevin_McKernan @MdBreathe @newstart_2024blog.maryannedemasi.com/p/the-silencin…Image
As a scientific writer and researcher, I’ve witnessed the decline of medical journals firsthand. I interviews Rita Redberg, ex-EIC of @JAMAInternalMed, Richard Smith ex EIC of @bmj_latest and John Ioannidis, the most cited scientist in the world blog.maryannedemasi.com/p/are-medical-…Image
Never have I seen a more absurd example of this decay than the retraction of a hypothesis paper—yes, a hypothesis—authored by @SabinehazanMD in Frontiers in Microbiology.
In May 2023—more than a year after the article was peer-reviewed and published—the journal retracted the paper following a series of complaints on PubPeer, offering only a vague explanation about “scientific soundness.”Image
Read 8 tweets
Apr 7
💉Should you take a flu shot?
Despite evidence of poor efficacy, advocates say "it's better than nothing".
Read why that's a bad argument? 👇👇


@Jikkyleaks @MdBreathe @Liz_Wheeler @RobertKennedyJr @CartlandDavidblog.maryannedemasi.com/p/should-you-t…Image
In 2013, Dr Peter Doshi wrote an editorial in @JAMAInternalMed, titled "Influenza Vaccines
Time for a Rethink." He argued that flu vaccines do not reliably reduce outcomes that matter to patients—such as hospitalisation or death.

This is supported by Cochrane reviews.
jamanetwork.com/journals/jamai…Image
Victoria & New South Wales mandates the flu jab for healthcare workers to protect vulnerable patients. But a Cochrane review found vaccinating healthcare workers made “little or no difference to the number of residents who get flu or go to hospital with a chest infection.”cochrane.org/CD005187/CENTR…
Read 7 tweets

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