Definition of acute SMM: severe, life threatening event during pregnancy & within 6 weeks of delivery. @NPEU_UKOSS provides UK wide high quality obstetric surveillance. Deaths, while uncommon, investigated in depth.
SMM at a population level. Study population derivation. #OBAnes#OAA23ASM
Coding SMM in Scotland: diagnoses & procedures. Sepsis and esclampsia most frequent diagnoses; ICU admission & wound re-closure most common procedures. Peuperal sepsis leading cause of admission to any critical care facility. SMM incidence 50 per 1000 pregnancies. #OBAnes… twitter.com/i/web/status/1…
Risk factors for SMM: previous cesarean section, multiple gestation, African/ Middle East/ Asian descent, increased BMI, and pre-existing comorbidities have increased OR; parity protective? Increased SMM in recent years, more readily diagnosed or admitted to critical care? Or… twitter.com/i/web/status/1…
Short term outcomes of SMM: LoS >7 days, death, stillbirth, late second trimester loss. #OBAnes#OAA23ASM
Is coding accurate? Peuperal sepsis ICD-10 code. Definition closer to SMM: infection + organ dysfunction or peuperal sepsis + critical care admission. PPH excluded. #OBAnes#OAA23ASM
Media coverage - balanced? Key points: SMM as defined occurs in 1% of pregnancies. Definition requires refinement & validation. Risk factors for SMM increasing. SMM strongly linked to maternal death, stillbirth/ fetal loss, increase LoS. #OBAnes#OAA23ASM
Longer term outcomes. Consequences: PTSD, distrust of system. Surviving critical illness - post intensive care syndrome. Affects families and patients: mental health, cognitive and physical fall out —> quality of life impacts. #OBAnes#OAA23ASM
Study design. One-year mortality: 200 per 100,000 if admitted to ICU (2.5 per 100,000 if not). 42day readmission 26.7%, 42day to one-year readmission 14.1% (if admitted to ICU). Longer term outcomes: mortality, hospital readmission and NB psychiatric hospital admission.… twitter.com/i/web/status/1…
Implications. High emergency readmissions. Post ICU follow-up services ideal, but still patchy. Psychological support probably lacking. Maternity specific adaptations to existing services required? #OBAnes#OAA23ASM
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@rr_metabolicmed presents the Bruce Scott Lecture 2023 at #OAA23ASM: Obesity & diabetes in pregnancy - legacy for the child. #OBAnes
Study of 1.3 million pregnant women reveals global obesity crisis: 75% pregnant women fail to achieve healthy weight gain during pregnancy, leading to preventable adverse health consequences for both the women and their babies. Obesity has strong evidence for increased risk of… twitter.com/i/web/status/1…
Maternal obesity and offspring cardiovascular disease: maternal obesity increases offspring cardiovascular death (Hazard ratio [all cause mortality] = 1.35). At current UK maternal obesity rates, this equates to extra 650 deaths before age 50 each year. The Hazard ratio for type… twitter.com/i/web/status/1…
Physiological changes in pregnancy. Normal LFT/ laboratory changes. #OBAnes#OAA23ASM
Causes of liver derangement in pregnancy: flare of pre-existing liver disease (known or unknown). Incidence of pregnancy in people with chronic liver disease at King’s College Hospital. Historically, cirrhotic patients have been infertile d/t anovulation. Population based data… twitter.com/i/web/status/1…
Prof Donald Peebles on Embedding Maternal Medicine Networks at #OAA23ASM. Knowing who to call is half the solution to any problem? (Touched on by @elsmere_g during #OBAnes session at #Anaesthesia2023)
Direct maternal mortality rate per 100,000 maternities had been decreasing over the last 2 decades, but should a remarkable upswing since 2018, not all accounted for by #COVID19. @mbrrace outlined a case for change: most parts of UK have MDT, but make up variable most without… twitter.com/i/web/status/1…
The Maternal Medicine Network (MMN) mandate: ensure timely access to specialist advice and care at all stages of pregnancy. Development of Maternal Medicine specialist centres as regional hub & spoke model = urgent national priority (@DOckendenLtd report)
Why is teamwork important in OB/ #OBAnes? @mbrrace suggests some lessons to be learned. Prompt action is arguably reliant on good communication, within & between teams. Involving consultant/ specialist care early has been a theme for over a decade. #OAA23ASM
@DOckendenLtd’ final report highlighted “conflicting agendas and poor teamwork” contribute to adverse maternal & neonatal outcomes? So how do we create good teams?
The history of @NAPs_RCoA projects and key findings for #OBAnes over the years (failed intubation NAP4 1:390, recent US data 1:808 - gotten better or different methodology?) #OAA23ASM