Kevin McKernan Profile picture
Jun 19 8 tweets 4 min read Twitter logo Read on Twitter
I've seen someone authoritatively claim ONLY the SV40 polyA signal is present in the vaccine.

This person never looked at the sequence.
Here is the region with the SV40 promoter, The 72bp bidirectional SV40 Enhancer, and the SV40 Ori.

nature.com/articles/s4141… Image
SV40 origin is only active in people who have SV40 T-Antigen expressed. Many people (100M) are SV40 infected suggesting they may be present in these individuals

ncbi.nlm.nih.gov/pmc/articles/P…
There is an SV40 poly A signal downstream of the F1 origin but this is omits many of the other SV40 components in expression plasmid. Image
What is the F1 origin?
This can be used to make single stranded copies of the plasmid DNA for viral packaging in mammalian cells or bacterial strains.
The direction of the yellow arrow directs the + strand of synthesis.

nature.com/articles/s4141…
The above paper is where much of the cancer risk of SV40 comes from. This relates to people infected with the full 5,234 viral genome, not just the components in the expression plasmid. What happens with SV40 infected people are vaccinated? Image
Seroprevalence is significant.
ncbi.nlm.nih.gov/pmc/articles/P…. Image
I don't profess to know what all this means. I know enough to know it should be disclosed given the guidelines that are in place.

This is the opposite of disclosure. No DNA sequence provided to the EMA. Just a vector map with this stuff missing. Image

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More from @Kevin_McKernan

Jun 18
While @PeterHotez squirms over a @joerogan debate, he is waving around his charity.

Is it pure charity?

The claim is that they made a patent-free vaccine...

which requires licenses and clinical trial data that is thin or hard to come by.

sec.gov/Archives/edgar… Image
Patents are not the only way to secure business interests. Trademarks, trade secrets and licensing deals can be just as potent.
Corbevax TM has a trademark and many licensing deals are in place to deliver this cheap vaccine. It is cheap and 'likely' a safer approach than mRNA
Read 18 tweets
Jun 16
There is a difference in saying SV40 promoters are not carcinogenic because they are missing the T-antigen …
And saying
We don’t know what will happen regarding genome integration.. or what will happen to the substantial part of the population already infected with SV40 virus. Image
A non trivial amount of the population already has SV40 virus capable of making the T antigen.

Injecting SV40 promoters and the SV40 origin into these patients may have unintended consequences. Image
Saying something doesn’t cause cancer and saying we don’t know are very different statements the fact checkers don’t like to face.

I go back to Keith Pedens work at the FDA looking at genome integration risks and oncogenesis.

While there isn’t direct evidence yet… Image
Read 4 tweets
Jun 15
My presentation at the FDA VRBPAC meeting today.
49 minutes in.
Image
Image
Read 17 tweets
Jun 14
I like JJ Couey.

Since he doesn’t have much of a platform on Twitter and he feels l slighted him ‘dunking’ on his IC hypothesis,

It’s only fair I air his grievances to my whole audience. 4:20 mins in.
Nice 420!

analytics.twitter.com/mob_idsync_cli…
I have had emails with JJ going back to December alerting him to what I saw as some of the holes in his Infectious clone hypothesis.

It’s not fair to say I sprung a dunk on this. I would get asked repeatedly to address it and finally got tired of piecemeal explaining the issues.
So I wrote everything into one thread that probably felt like a blind sided attack since he’s not on Twitter. But most of this I had already aired to him offline.

I also took his feedback on a Substack I wrote on the topic and edited things.
Read 6 tweets
Jun 13
My experience with PubPeer has been very poor.
Wont let me register as my domain name at Medicinal genomics is not 'recognized'.

So if anyone else is registered and wants to point out this fake trace in a Drosten paper, please do.
There is no way... Image
The primers depicted in that extended data fig 1 generated those sanger traces as sanger doesnt sequence your primers. If a different set of primers were used to 'validate' the qPCR assay,
1)what were they?
2)using different primers to validate the fidelity of your PCR is fake
You are no longer measuring the fidelity of you PCR primers if you use a different one for sequencing.
The reverse primer can be read with Sanger if its close enough to the Forward primer (under 600bp). Must be on the 3' of the sanger trace for this to happen.
Read 5 tweets
Jun 10
Oncologist’s employer takes Pfizer donations.
Claims it’s against his institutions policy to sequence his fresh vaccines.
Demands I send them our expired vials that he spent days chastising the veracity of.

Never declares this conflict.

Our primers are public.
Conflicted parties don’t advance the field.

David has exposed himself as having zero impartiality on the topic.

He has access to fresh vials but won’t touch those.
He wants our vials which he claimed were insufficient for publication and an embarrassment to work with.
He has all the tools he needs to replicate this and address the problems he’s gone on public record with.

But he’s not doing this.

osf.io/b9t7m/
Read 8 tweets

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