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Dr Elisa Perego Profile picture
@elisaperego78
Jun 19 • 6 tweets • 2 min read Twitter logo Read on Twitter
Omicron infection can lead to #LongCovid in a significant proportion of nonhospitalized patients 6–12 months after infection. A study on 6242 people of all ages from Hong Kong infected up to 6 May 2022, with Covid proven by positive PCR or RAT

onlinelibrary.wiley.com/doi/10.1002/jm…
Unfortunately, the article is beahind a paywall, so I am unable to evaluate appropriately methods and limitations of the study. I have only access to the abstract
"This is a large-scale retrospective study. A total of 6242 of 12 950 nonhospitalized subjects of all ages with [confirmed] SARS-CoV-2 during the Omicron dominant outbreak .. in Hong Kong were included. Prevalence of long COVID, symptom frequency, and risk factors were analyzed"
"3,430 (55.0%) subjects reported at least one long COVID symptom. The most reported symptom was fatigue (1241, 36.2%). [unfortunately here I am not able to see which symptoms were evaluated and how were collected as the paper is beahind a paywall]
Associated risk factors were "Female gender, middle age, obesity, comorbidities, vaccination after infection, having more symptoms, and presenting fatigue/chest tightness/headache/diarrhea in the acute stage of illness" [again, I can't see the details because of the paywall]
"Patients who had received three or more doses of vaccine were not associated with a lower risk of long COVID" [and again here I don't have access to the details because of the paywall i.e. if at least vaccination decreased LC severity. But this still warrants attention]

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More from @elisaperego78

Dr Elisa Perego Profile picture
Jun 20
#LongCovid is an heterogeneous disease with multiple manifestations that might range from subclinical to fatal. It can basically affect all organs and body systems. Long Covid was openly recognized by the WHO in August 2020 after intense advocacy from Covid survivors
The first descriptions of #LongCovid came from social media like Twitter. People in early hotspots were often left at home with no medical support in collapsed healthcare systems. They took on social media to raise the alarm about the real nature of Covid

sciencedirect.com/science/articl…
Rather than being a "short" respiratory disease, dangerous only in the "old and sick", as said in many media and by many policymakers, Covid was a prolonged, multifaceted, multi-system disease that could hit badly even those deemed to be at "low risk"

sciencedirect.com/science/articl…
Read 6 tweets
Dr Elisa Perego Profile picture
Jun 19
A small study but it shows ➡️ a marked increase of bone marrow edema in the phalanges of hands and feet after the beginning of the covid pandemic in the study group, suggesting SARS-CoV-2 infection as a potential trigger

#LongCovid

link.springer.com/article/10.100…
The patients could present with pain and skin erythema, similar to the "covid toes". Analysis of the MRI scans in the study showed similarities to Raynaud's phenomenon. The pandemic increase was thirteenfold (13 times higher than pre-), which was statistically significant
Most cases, but not all, were found in middle-aged (mean 40.3 ± 14,3 years) female patients (80.0%), with no comorbidities. A previous SARS-CoV-2 infection was documented only in some cases (this doesn't exclude an asymptomatic/pauci-symptomatic or undocumented infection)
Read 7 tweets
Dr Elisa Perego Profile picture
Jun 18
I've concerns about the way Tony Fauci frames our fight with Covid | a bit of a long thread. First, there is a big difference between pursuing eradication, and surrender to the virus through "living with/mass infection" policies. Which is what we, actually, have now
Second, I'm not saying that SARS-CoV-2 can be eradicated in the current sociopolitical context. But, the virus has been eliminated multiple times in multiple countries, or came close to. This pointed to elimination or hard containment being possible
The decision not to pursue eradication (global elimination) or (local) elimination has been dictated, in my opinion, more by socio-economic than public health concerns. I'm not saying eradication was necessarily possible.
Read 11 tweets
Dr Elisa Perego Profile picture
Jun 17
A review of potential impacts of SARS-CoV-2 on the parathyroid glands in acute and #LongCovid. Parathyroid dysfunction has been known to lead to alterations e.g. in the blood calcium levels and bone metabolism.

link.springer.com/article/10.100…
The parathyroid glands are two pairs of glands near the thyroid in the neck. Their function is to secrete the parathyroid hormone (PTH) which is important to maintain calcium's and phosphate's optimal levels. You can have hyper- or hypoparathyroidism

en.m.wikipedia.org/wiki/Parathyro…
The review looked at the impact of SARS-CoV-2 infection on the parathyroid, with acute and prolonged manifestations "Recent findings documented the involvement of the SARS-CoV-2 in inducing various parathyroid disorders including hypoparathyroidism and hypocalcemia"
Read 7 tweets
Dr Elisa Perego Profile picture
Jun 16
Cycling star Gino Mäder, 26, has died after suffering a devastating crash and fall in a ravine during the Tour de Suisse on Thursday.

theguardian.com/sport/2023/jun…
Gino Mäder, 26, has just come back to racing after missing the 2023 Giro in May after not recovering from Covid in April. Gino had contracted Covid, too, at the same Tour de Suisse in 2022, for which he missed the top Tour de France the same year

I felt shock and sadness in hearing the news today. I've been looking at the experiences of elite sportspeople after Covid to see how they fared after infection. Gino Mäder was one I was following. Not linking the two, but it was with shock I heard about his name, the fatal fall
Read 6 tweets
Dr Elisa Perego Profile picture
Jun 15
New CDC data shows since 2019, hospital fungal infections have increased by 8.5 percent. COVID-19 is a "substantial risk factor" for patients contracting certain fungal infections. The new "data reveals the effect that risk factor had inside hospitals."
beckershospitalreview.com/public-health/…
"CDC experts also found that patients admitted with COVID-19-associated fungal infections are more likely to be in Hispanic men around 63 years old on average."
"Individuals who were hospitalized with a COVID-19-associated fungal infection were also more likely to experience an ICU admission, longer hospital stays, invasive medical ventilation, or death compared to individuals who had a fungal infection not related to COVID-19."
Read 4 tweets

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