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Christie Laura Grace

Sep 29, 2023 • 32 tweets • 12 min read • Read on X

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1/ 🧵How SURFACE CHARGE (zeta potential) on LNP DIRECTS WHERE in body it goes (LIVER then distribute, OR, DIRECTLY TO SPLEEN, or DIRECTLY TO HEART OR LUNGS) , AND WHY this explains multiple types of ADVERSE EVENTS, including the recent FATAL HEART STUDY that is being shared.

2/CHARGES: WATCH video (refresher for some): This video (Mr. Anderson) explains how positive (+), negative (-), and neutral (0) items interact. How even something WITH a + CHARGE can ATTACH to something NEUTRAL.
Trying to use basic explanations for all.

3/ LNP: My silly drawing. NOT ALL lipids will be discussed. WE are FOCUSING on CHARGE.
The RED backward S= negatively charged mod RNA (-). The GREEN plus (+) is POSITIVELY charged ionizable lipid. They stick together (better pic included). Also; Pfizer's doc: zeta= -3 mV.

4/ ONLY watch video if you know science. In the video/study, SCIENTISTS, took LNP w/ RNA (-) w/ pos. lipids (+) and injected into mice--different kinds--some w/ equal (-)/(+)=neutral, some more (+), some more (-), some VERY negative(--), and tracked

5/ WHERE in mouse's body LNP/RNA went, according to CHARGE. Zeta potential is complicated. It has factors: SIZE of LNP, Amount of positive (+) and negative (-) charges in it, surface charge (outer layer) in respect to pH, and other things. This is watered down, for simplicity.

6/ The scientists at the NANO company and OTHERS (not conspiracy theory, not my theory), FOUND that if they adjusted the RATIO of positive (+) to negative charges (-) inside the LIPID NANOPARTICLE, they found the LNP did NOT go to the LIVER and distribute, as initially thought.

7. The scientists found that, if the LNP has a surface charge that is NEUTRAL (ish), it goes to LIVER and distributes to other areas of the body, as seen in initial studies, and clinical trial (sans the DNA plasmids, yes?) This was with a zeta potential approx. - 3 millivolts

8/ BUT if the LNP had a higher (+) POSITIVE CHARGE, it did NOT go to the LIVER and distribute--it goes to LUNGS. IF it has slightly negative (-) charge, it goes to SPLEEN. If it has MORE NEGATIVE (--), it can LEAK into VASCULAR (HEART, vein, artery) and cause bad things.

9/ If the charge is positive (+), it is zipping right to the lungs. It does not matter if you aspirate. This is by injecting into the MUSCLE, not just IV. MUSCLE. It could cause injury in lung (PE?). If a little negative, it goes to spleen. If VERY negative, it goes to HEART.

10/ It can also cause (if very negative charge): CLOTS (binding to platelet factor 4--proven in AstraZeneca study), create a PROTEIN CORONA (the LNP will bind with albumin, other plasma proteins--diff thread)--possible injury, and express spike in endothelium of vascular.

11/ Now, let us look at the basic construction of the LNP in very simple terms for as many to understand as possible. LNP is made of cholesterol, DSPC, "unprotonated" (has not received a charge yet from H+) ionizable lipids, charged (+) lipids, PEG, and modRNA (-) charge.

12/ as seen above, the LNP is self-assembling (this is a term certain "people" are taking the wrong way--the LNP assembles in the LAB, because of charges and contents.) However, the companies must have measured the "charge" on the LNP, without DNA plasmids. They did this w/IVT.

13/ (this is old drawing, before it was shared that the DNA plasmids are in pieces. The purple circle in NEXT drawing is the DNA plasmid. The Red backward S is still modRNA, and green plus (+) is positively charged lipids.
First, it was thought that the LNP only had modRNA in it

14/ But instead of just modRNA, and lipids in mix, there is DNA plasmids in the mix when the LNP is forming. The measurement of the zeta potential, -3 mV was done using a process to make the LNP and modRNA using IVT (no plasmids). Hence, might not be accurate measured charge.

15/ Two things could have happened. You could have DNA plasmid pieces (excuse the plasmid circles as they represent the DNA plasmid) which are (-) surrounded by pos lipids (+) forming lipoplex--not part of RNA LNP structure. OR, DNA/RNA lipopolyplex (modRNA AND DNA inside). Now,

16/ The DNA polyplex by itself should have a more positive charge (going to the lungs!). And according to the study precision nano and others did, highly negative is going to vascular system, which would account, for what was described previously. This new study just came out.

17/ This study says: ". . VACCINE WAS NOT DETECTED IN THE MEDIASTINAL LYMPH NODES, SPLEEN, OR LIVER. VACCINE WAS DETECTED IN THE MYOCARDIUM IN A SUBSET OF PATIENTS VACCINATED WITHIN 30 DAYS OF DEATH."

nature.com/articles/s4154…

18/ "Serious adverse complications due to these vaccines are uncommon and may include anaphylactic reactions, myocarditis, pericarditis, myocardial infarction, cerebral sinus thrombosis, stroke, pulmonary embolism, neuropathies, and autoimmune hepatitis"
We know, from studies,

19/ That when you alter the ratio of (+) charged lipids to negative charged (-) modRNA, this would change where it goes in the body. The contamination of DNA plasmids MUST be CHANGING the ZETA potential and overall charge of the LNP, causing it, sometimes, to go to vascular/lung

20/ Another thing that could be happening, in addition to DNA plasmids changing the zeta potential (charge) is the LNP is breaking down during the freeze/thaw process, and parts can leak out, changing the overall charge as well. Dr. Ko and De, and others proved.

21/ Negative charges also cause clots (negatively charged liposomes) as shown above.
The introduction of the negatively charged DNA plasmids, at a rate of billions per dose, at 100 bp (base pair average, must be shifting zeta. It probably distributes UNEVENLY, which accounts

22/ for heterogeneity (differences) between batches and vials. Because it is not evenly distributed, there would be batch an vial variation. The FDA needs to investigate immediately, and need to immediately halt distribution.
The DNA plasmids are of significant concern.

23/

anandamide.substack.com/p/sequencing-o…
anandamide.substack.com/p/south-caroli…

24/

pubmed.ncbi.nlm.nih.gov/36588456/
nature.com/articles/s4200…

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(you could still watch--it just might melt the brain or confuse)

https://twitter.com/_HeartofGrace_/status/1706434015148810686

A thread on the CpG motif contained within the DNA plasmid and what the immune system and other impacts it most likely is causing.
(multiple studies to back)

https://twitter.com/_HeartofGrace_/status/1706434015148810686

@kharaguchi

I was limited to 24 tweets in thread. If the DNA plasmids have entered the LNP, this means it is shifting the zeta in a negative direction. The calculations have been done assuming size differences and using two different formula sets.
Approximations using base pair average of 100 was used.
Some may contain far more DNA plasmids than others which would cause it to shift greater into the negative direction.
Because not everyone is having these effects, It must be the case that some the lipid nanoparticle have far more DNA plasmids in them than others which would account for the differences in charge. The lipid nanoparticle also vary in size which means, depending on some factors, so would zeta.
The opposite of what most would assume to be true is not.

The smaller the LNP, the stronger the charge.

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Christie Laura Grace

@_HeartofGrace_

Mar 26

🚨💉🦠PREPRINT! Journal has it now. NEW theoretical MULTI AXIS MECHANSM by spike protein, SHARED DISEASE and worse between LONG C@VID and C@VID V@CCINATION via ion channel dysfunction, and AUTO ANTIBODIES TO THE PROTEINS OF THE SODIUM CHANNEL!
Short summary below👇

THIS IS THE SHARED THEORETICAL MECHANISM:

I am about to release two more papers to preprint and journals in next 24 hours on worse symptoms, clots, and cancer.

I cannot write the summary I wanted, I have to go back to writing. This is al I got.
I must get back to writing, and sleep sometime.

✅Ion channels are tiny gateways in our cells that control how ions (like sodium, potassium, and calcium) move in and out. This

is crucial for sending signals in our nerves, regulating our immune system, and keeping our cells functioning properly.

This spans ALL of our physiological processes--ALL CELLS.

When ion channels don’t work correctly— ion channel dysfunction can cause a wide range of health issues, including neurological disorders, chronic pain, and immune system problems. Mast cell. So many things--head to toe. Not just nerve symptoms. All symptoms. Clots, All of it. Vascular permeability. All of it.

I am completing deeper dive on this because there just was not enough room in the paper to do it--exact further mechanisms on organ injury and cancer. This includes but not limited to myocarditis and organ injury. Antibodies against the areas and more with dysfunction of the ion channels in tandem with cGAS STING, MACROPHAGE, ZETA PPOTENTIAL, HORMONES, GENETIC MUTAIONS, PAMPS and DAMPS, and more.

Both C@VID-19 infection and v@ccination MIGHT, theoretically, contribute to ion channel dysfunction through immune system overactivation, chronic inflammation, and the production of autoantibodies that mistakenly attack ion channels.

The cGAS-STING pathway, which detects viral threats, can become overactivated, leading to persistent inflammation and autoimmune reactions. Additionally, the spike protein from SARS-CoV-2 shares structural similarities with certain ion channel proteins, which may lead the immune system to mistakenly target these channels, causing transient or chronic dysfunction. In some cases, this immune response may be self-limiting, resolving over time, while in others, it may lead to long-term autoantibody production, resulting in sustained neurological, cardiovascular, and muscular symptoms.

cGAS AMPLIFIES the feedback loops, while macrophages get dysregulated in the consumption of the charged lipids, the vessels in capillaries and arteries become permeable, clots--next paper in 24 hours will show full on mechanisms--tissue damage. The eyes, the whole body. Brain. IN SOME PEOPLE.

Can cause people to have all kinds of things getting misdiagnosed or as secondary effects. Bed bound. Death

This could if, THEORETICALLY, with severe gain of function mutations present in ion channel encoding for proteins in ion channel, cause cascade of immune system, autoantibody attack against proteins of ion channel, appear sepsis like, and cause death.

Heart attack.. SIDS. Sudden adult death.

FOR WOMEN--this paper shows that estrogen has an impact on ION CHANNELS and how that if a woman is menstruating and still has estrogen present, each month, a flare may occur, and cause worsening autoimmunity, which is not to say men have not suffered, but why WOMEN are suffering from these symptoms MORE. Could be worse all the time. Immune reaction worse. Initial injury worse.

Also, WHITE EURPOEANS and middle eastern background compared to African, Asia, and indigenous, while still suffering harms, have higher levels of STING activation due to variation in STING pathway making more susceptible to dysregulation, meaning more autoimmunity and harms than others in white and middle eastern background.

ALSO--women have dysregulation in gut brain axis due to estrogen.

Due to their role in nerve signaling, muscle function, immune regulation, and cardiovascular stability, dysfunctional ion channels can lead to widespread symptoms, including
SFN LIKE symptoms, AIDP LIKE symptoms. GBS like symptoms, transverse myelitis,
tachycardia, bradycardia, palpitations, arrhythmias, hypotension, hypertension, dizziness, fainting, syncope, chest pain, blood pooling in the legs, poor circulation, orthostatic intolerance, POTS-like symptoms, brain fog, migraines, chronic headaches, vertigo, tingling, numbness, neuropathy, tremors, muscle weakness, myoclonus, ataxia, seizures, hypersensitivity to light and sound, temperature dysregulation, fatigue, autonomic dysfunction, memory problems, difficulty concentrating, muscle cramps, muscle spasms, muscle stiffness, twitching, myopathy, exercise intolerance, paralysis episodes, myalgia, difficulty swallowing, loss of fine motor control, nausea, vomiting, bloating, diarrhea, constipation, gastroparesis, IBS, abdominal pain, acid reflux, swallowing difficulties, shortness of breath, hunger, hyperventilation, irregular breathing, chest tightness, chronic cough, respiratory muscle weakness, hormonal imbalances, ovarian dysfunction, irregular periods, amenorrhea, infertility, PCOS, thyroid dysfunction, insulin resistance, unexplained weight loss or gain, frequent urination, bladder dysfunction, incontinence, difficulty urinating, interstitial cystitis, kidney dysfunction, chronic inflammation, autoimmune disease, increased susceptibility to infections, mast cell activation syndrome, histamine intolerance, allergies, skin rashes, hives, anxiety, panic attacks, depression, mood swings, irritability, insomnia, hypersomnia, depersonalization, derealization, heat intolerance, cold intolerance, excessive sweating, lack of sweating, lightheadedness, vision disturbances, difficulty adjusting to light changes, tinnitus, and sensitivity to sound, smell, or touch.

This is NOT the complete list!

Organ injury, hypo or hyper thyroid like symptoms--that whole list on the Pfizer data dump: run through them. Specific ion channels are 4--also acetylcholine channel.

The cGAS-STING pathway detects foreign or self damaged DNA inside cells, triggering an immune response.

When SARS-CoV-2 infects cells or lingers as viral remnants, it can overactivate, leading to prolonged immune responses that may mistakenly target self-proteins, including ion channels. This process can contribute to autoantibody formation against ion channels, which may explain persistent symptoms following COVID-19 infection or, in rare cases, vaccination. THIS is combined with macrophage polarization and spike protein on ion channels-theoretical.

Because the spike protein shares structural similarities with certain ion channels, the immune system may temporarily mistake ion channels for the virus, leading to transient dysfunction. In some cases, once the immune system resets, symptoms resolve. However, in other individuals, this misdirected immune response is chronic, leading to persistent autoimmune-mediated ion channel dysfunction.

This could explain why some individuals experience long-term neurological, cardiovascular, or muscular issues after infection or vaccination.

This does not say that sv40 and biotech plasmids with other properties of spike are not present. This paper could not address that and does not discount.

Add in dna plasmids amplifying cgas sting and macrophage and charged lipids impacting further, and recipe for disaster.

The possibility of transient versus chronic ion channel dysfunction due to cGAS-STING activation and autoantibodies is URGENT need for testing for ion channel autoantibodies in individuals experiencing post-COVID or post-vaccine symptoms.

Identifying these autoantibodies could lead to better-targeted treatments, distinguishing between cases that may resolve over time versus those requiring immunotherapy. Research into the mechanisms behind autoimmune ion channel dysfunction will be crucial for improving diagnosis and treatment options for those affected by these complex conditions.

There is current drugs present that cost under ten dollars for ion channel dysfunction like tegretol. I am not a medical doc and this is not treating or DXing anything. Always check with your doc.

People are suffering spread the word. This is theoretical.

For those with labs, get testing!!!!

I have to go now and write.
I am ONLY answering emails and calls right now form doctors I am arranging meetings with. If you have questions, ask the experts in your circles.

I cannot chat about this or answer questions. If you want summaries, load into grok or whatever you choose. I must go.

I have work to do and messaging slows me down.

2/ The cGAS-STING Pathway, Ion Channel Dysregulation, and Immune Responses: Implications for Autoimmunity, Inflammation, Long COVID, and Post-Vaccination Responses

osf.io/preprints/osf/…

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People told me to wait-I cannot. I am writing fast and two more are coming in 48 hours.
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Read 12 tweets

Christie Laura Grace

@_HeartofGrace_

Feb 24

https://twitter.com/_HeartofGrace_/status/1780785761660383613

1/ 🚨💉🧬 Hot off the presses, March 2025, almost one year later, "next gen mRNA"

"CpG ODN-adjuvanted, alum-adsorbed, virus-like particle (VLP) vaccine displaying the hexaproline stabilized Spike (S) protein and the Nucleocapsid, Membrane, and Envelope proteins of SARS-CoV-2."

https://twitter.com/_HeartofGrace_/status/1780785761660383613

2/

(This requires access, so I will screen shot) sciencedirect.com/science/articl…

3/ The sentence reads like a nightmare to me: " CpG ODN-adjuvanted, alum-adsorbed, virus-like particle (VLP) vaccine displaying the hexaproline stabilized Spike (S) protein and the Nucleocapsid, Membrane, and Envelope proteins of SARS-CoV-2."

Read 29 tweets

Christie Laura Grace

@_HeartofGrace_

Feb 23

The material that has gone into humans is research grade at best. That means RG. Fit for animals but not humans.
I dare say it was even fit for animals.

I know because it was my job.

I know the difference between research grade, cGMP (which still has its issues, One just need to research any 483 form with the FDA, or having worked designing the stuff).

I designed recombinant proteins custom, fusion proteins with specialty RNA, lipids, custom work for those who have suffered from genetic disease and cancer.

Those are small batches for clinical trials that are highly filtered by expert teams with all eyes on every vial, clean as can be, with small cohorts of maybe a few dozen people, and a liter of material. And with all that, there is still side effects because that platform is flawed on multiple levels. I can cite study after study right now on the reasons why it that is, and to pull them all from my profile, and so could others.

Sludge was allowed to be injected into over 5 billion people.

Non-coding RNA can cause cancer. Fact.

Multiple studies including done by experts who out rank anyone here in the US or the UK over in Korea have done the tests stating that the modified RNA is breaking inside the LNP. This renders it non coding, which means it can't make anything and it's only function is going to be to interfere with other cellular mechanisms with the concern of causing cancer. It can cause transient concerns which can activate pathways regardless if it is degraded in the cells.

The lipids themselves have been used in multiple studies injected into animals and have been found to cause disease and cancer because of the disruption of the continual injection and what damage has occurred as a result of exhaustion of the mononuclear phagocyte system. That's something you are not familiar with and what I'm stating here is not known to most people reading this.

Positively charged lipids have an impact on cellular function and if they aggregate an areas they can do damage.

The modified RNA has been shown to have oncogenic properties.

This modified RNA also has been known to frame shift inside the ribosome causing junk proteins to be made which is irrelevant because....

Moderna did their own study with their own researchers only a couple of years ago which they paid for using special equipment and they found (packer et Al 2021) that the impurities in the positively charged lipids are covalently bonding to any nucleic acid they come in contact with including the modified RNA inside the lipid nanoparticle creating what is called an adduct and it is occurring in about 10 spots per piece of RNA in each of the particles which, will cause the same issue and cause the slippage in the ribosome causing non-coding issues which means we're back to the cancer possibility with the junk protein being made with aggregation and misfold of a spike protein that is already known to have amyloid properties related to neurodegenerative disease.

The lipid nanoparticle itself contains high levels of the original starter biotech plasmid which was housed in e coli and grown up to make the modified RNA. On this piece of plasmid which is circular which you can look up anywhere, It contains multiple parts and the one moderna used is slightly different than the one Pfizer used. There is a spot for the protein gene of interest. I can show you a video of you would like and you are a smart guy and it was done by a biotechnology student. There's also an antibiotic resistant gene, And a few other sections and on the Pfizer plasmid there is what is called the SV40 promoter which is minus the large T antigen However is still a very strong promoter. The CMv promoter also a strong promoter.

These are circular and they were not digested properly or removed from any of the batches and it all went into humans.

The scale of harm that could theoretically be on deck is unlike anything our civilization has ever seen when it comes to the potential harms.

I've heard people say they don't want to scare people.

The amount of cancer and autoimmune around myself and others is staggering. People in their 30s at my clinic have cancer. People in their twenties. 17-year-olds with brain tumors. A 9-year-old boy just got taken to the children's hospital here a couple months ago with myocarditis right after... Guess what?

That promoter can have transient expression in ways I'm not typing here because I'm writing a paper on it and when it's shown exactly what it is doing in cells aside from its other activity and how it can interfere with the proteome, in ways that people are not currently checking which will take time and sales turn over and the proteome is going to start replacing and making adjustments and fusion proteins are going to start to occur in some people (if they aren't already.... Fusion protein is often present in lymphoma, piers).

Then we have the issue with biodistribution and they lied about the whole thing including studies that prove more than once with full data to back peer-reviewed that the particle itself has a different biodistribution in pregnant animals compared to non-pregnant animals that it goes to the lymph nodes 8 times more and that means everything is going to the lymph nodes eight times more including eight times the spike protein eight times the RNA 8 times the positively charged lipids eight times the DNA plasmid contamination and any other god-awful contamination that exists that we know about which is occurring often like bacteria and other plasmids and cross-contamination from other projects because it is a well-known fact that this occurs and any 483 will show you this in every other plant on the planet.

This thing was never going to save anyone.

This needs to be taken very seriously.

@piersmorgan PS

I ranted that all from my phone using voice to text. I apologize for any grammatical errors

1/ plasmid dna can be taken up by a lymphocytes when injected into the muscle.

That's the biotech plasmid.

In pregnant females this happens at eight times the volume regarding lipid nanoparticles going into their lymph nodes while they are experiencing changes in their immune system but it also goes to the placenta.

Typing from my phone here

x.com/_HeartofGrace_…

Read 35 tweets

Christie Laura Grace

@_HeartofGrace_

Jan 25

1/ Digital Twins and Cancer.
This has already begun.
There's talk about how this translates into the human, physical world. This has already begun with the use of what are called organoids, which Harvard was and others were investigating, before it gained traction.

2/ you can read here about the use of a digital twin and cancer.

. sciencedirect.com/science/articl…

3/ the use of organoids for customized, personalized cancer treatment is already happening, privately. You're just not hearing about it. In 2017, HARVARD researchers started using organoids.

Read 19 tweets

Christie Laura Grace

@_HeartofGrace_

Dec 31, 2024

https://twitter.com/Ken__kaneki33/status/1873662544700969202

1/ 🚨"35-year-old woman contracted Lou Gehrig's disease after her first Pfizer dose."
ACTIVATION of DORMANT GENES in BOTH ADENOVIRUS AND RNA BASED.
These "products" like adenovirus and RNA/DNA can be DORMANT (see linked thread) and then become ACTIVE. Not just cancer :(
READ👇

https://twitter.com/Ken__kaneki33/status/1873662544700969202

2/ Charcot's disease is amyotrophic lateral sclerosis

'Charcot's Disease' is a progressive and fatal

progressive death of motor neurons

.ama-assn.org/delivering-car…

3/ "New-Onset Amyotrophic Lateral Sclerosis in a Patient who Received the J&J/Janssen COVID-19 Vaccine"

pmc.ncbi.nlm.nih.gov/articles/PMC10…

Read 26 tweets

Christie Laura Grace

@_HeartofGrace_

Dec 31, 2024

1/ 🚨 THEY KNEW.
"REACTIVATION" potential of ADENOVIRUS VECTORS used for "gene therapy", including the use of DNA PLASMID with LATENT and REACTIVATED STATES for BOTH and why this is important for SHEDDING and DISEASE.

🚨DATE of ISSUE: JANUARY 2020. COINCIDENCE?

2/ Pierre Kory and others have talked a lot about shedding--they are correct. The studies are on viral vectors--these are viral vectors. There are studies I have and so do others on this, but to drive it home--right here:

gillettechildrens.org/your-visit/pat…

3/ back to the first document: this was released 01/2020, right before the world was about to go into forced measures against the people, demanding they get injected with something that needs FIFTEEN YEARS of testing. The US had the gene sequence form CHINA in this moment.

Read 33 tweets

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