Maria Van Kerkhove Profile picture
Dec 31, 2023 24 tweets 5 min read Read on X
Long🧵 #COVID19 and where we are. I’m worried.

We are entering the 5th year of the pandemic and we are certainly in a different phase. This phase is marked by an evolving virus (with the XBB and BA.2 sublineages circulating and JN.1 becoming dominant).
It’s marked by reduced impact compared to the peak of #COVID19 a few years ago, but it’s still a global health threat and it’s still a pandemic causing far too many (re)infections, hospitalisations, deaths and long covid when tools exist to prevent them.

data.who.int/dashboards/cov…
It’s marked by co-circulation of many other pathogens eg flu, mycoplasma, RSV, etc.

Cases and hospitalisations for #COVID19 have been on the rise for months. Hospitals in many countries are burdened and overwhelmed from COVID and other pathogens, and deaths are on the rise.
It’s marked by complacency. I will never accept that there is an “acceptable level of dearth” (something I’m asked) for #COVID19.
We are talking about people, parents, children, people who laugh, love, dream

I wrote this last March and this still applies

Governments must not be complacent, individuals must not be complacent. We have all gone through something traumatic with #COVID19. The world shut down, we lost millions of our loved ones, billions have been personally affected by COVID. We cannot forget. @WHO will not forget
The legacy of #COVID19 must be strengthened health systems, with agility to scale up and down, to protect communities and health workers, improve the air we breathe, to provide access to safe, reliable & affordable PPE, tests, treatments & vaccines to ALL people in ALL countries.
To ensure we have comprehensive surveillance & sequencing systems that allow robust risk assessment to inform & empower people with good info. To protect & advance science. To support scientists & innovation & accept that as we learn, we change, we adjust, we course correct.
I’m worried that too many think #COVID19 is not something to worry about, that they need a new variant with a Greek letter to take this virus seriously. When we need to assign a Greek letter, we will not hesitate.
I’m worried we so badly want to move on that govts, many of whom have new leadership and have moved on, will forget the overflowing hospitals, the tents in parking lots for the sick, refrigerated trucks serving as morgues, burial grounds, fire pyres, exhausted health workers…
We can’t forget those who died alone and the people dying now- thousands each week. The hundreds of thousands in hospital right now fighting for their lives. Those suffering from #LongCOVID struggling each and every day….
These memories -still fresh- need to fuel & finance better health systems, equity, pandemic preparedness for current (#COVID19) & future threats IN THE CONTEXT of all of our other challenges of war, displacement, climate change. We have to do better. It’s hard. #PandemicAccord
As individuals, we are mourning, we are trying to heal, we are dealing with our own mental and physical health - I am trying to work on mine too - because what we went through was not “normal”.
The #COVID19 pandemic was not normal. It didn’t have to be this bad… and this wasn’t even the worst pandemic we need to prepare for.

So let’s talk the positive and the future because, while I’m worried, I’m also hopeful and optimistic.
I’m inspired by science, by innovation, by spirit and drive, by health workers and by my @WHO colleagues who - every single day - are on the front lines helping people whether this is in war zones or driving scientists to address unknowns to provide health solutions for people.
I’m grateful for science and innovation of PPE, improving ventilation, improving trust and communication, diagnostics, medications and clinical care, vaccines,

I’m thankful for the global advancements in surveillance, PCR & sequencing capacities, IPC, clinical care, emergency…
…medical teams, vaccine delivery, supply chain management, risk communication, community engagement and infodemic management, mass gathering management, emergency operations and coordination, R&D, etc.
These advancements must be maintained to deal with #COVID19 and all pathogens that have epidemic and pandemic potential: flu, dengue, mpox, cholera, nipah, Marburg, Ebola, RVF, CCHF, plague, MERS-CoV … and the next disease X.
I’m optimistic because of the good in people around the world despite the challenges we face. I’m optimistic because of the good in my colleagues @WHO led by @DrTedros and @DrMikeRyan.

@WHOWPRO @WHOEMRO @WHOAFRO @pahowho @WHO_Europe @WHOSEARO @rd_blueprint @WHOGOARN @UN …
About a year ago, I ended a talk @rpi with 4 questions and most of my talks now are structured around versions of these questions:

1) Do you remember? Do you really remember the first time you heard of this virus, this cluster of pneumonia in China? The fear of the unknown? The waiting for patients to reach your hospitals?

2) What will you do different? The next time … because it will happen again?
3) How will your work contribute now and for the next one? In whatever role you have… Because each of you played a role in this one and will in the next…. Thank you for your work.
4) How can you do better? I ask myself that every day, and I get up and try. @WHO is a learning organization and we have incredible people who work so hard - with the abilities provided to us by our member states - every. single. day.
We make mistakes. I make mistakes. But I get back out there every day and try to do better.

I’m in the arena. This is a huge responsibility I take seriously.

Last question: what are you doing? Your life is precious. You have so much to contribute.
Make a positive difference. Be kind. Stay alive. Live a happy, healthy and fulfilled life

Thank you health workers. Thank you public health professionals and scientists. Thank you community and youth leaders. Thank you CSOs and @WHO partners. Thank you all

Happy 2024 everyone!

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More from @mvankerkhove

Dec 19, 2023
🆕 @WHO TAG-VE Risk Evaluation of JN.1

Due to its rapidly increasing spread, WHO is classifying JN.1 as a separate variant of interest (VOI) from the parent lineage BA.2.86.  It was previously classified as VOI as part of BA.2.86 sublineages.

Short 🧵

who.int/activities/tra…
JN.1 is a descendent lineage of BA.2.86, with the earliest sample collected on 25 August 2023. In comparison with BA.2.86, JN.1 has the additional L455S mutation in the spike protein.

Full @WHO risk evaluation of JN.1 is available at link below
who.int/docs/default-s…
As of 16 December 2023, 7344 JN.1 sequences had been submitted to @GISAID from 41 countries, representing 27.1% of the globally available sequences in epidemiological week 48 (27 Nov to 3 Dec 2023). See Table 1 in risk evaluation.
Read 5 tweets
Jul 29, 2023
🧵Anyone who knows me knows that I despise the phrase “living with COVID”. We are living with #COVID19 & we must do it better. Governments must better manage COVID-19: prevent infections especially among those most at risk for severe disease & treat those infected & suffering…
…. This virus continues to circle the globe. It’s changing, it’s (re)infecting, it’s killing, it’s causing long term harm (#LongCOVID).

We will not ignore those suffering from LongCOVID and work harder to ensure better prevention and treatment.
Governments need to sustain critical actions to prevent infection (self test, ventilate, mask, etc), early detection w/ clinical care, vax/boosting those most at risk, sequencing to track variants and strong surveillance with continued reporting to @WHO
⬇️
who.int/emergencies/di…
Read 6 tweets
Jun 9, 2023
Long 🧵

It’s been just over a month since the lifting of the PHEIC for #COVID19 by @WHO @DrTedros.

While the world is moving on… and most people are able to live safely because they have some protection against developing severe disease and dying, they have good access to…
…health care, medicines and information, and they know how to keep themselves and loved ones safe from #COVID19… not all people around the world have this.

Governments can’t move on, must not forget. @WHO isn’t moving on…
…Our job is to inform all and support governments in maintaining the necessary life saving actions, to use our blood, sweat and tears that resulted in substantial gains in surveillance, clinical care, development and access to countermeasures, address underlying inequalities…
Read 13 tweets
Mar 16, 2023
. @WHO has updated its variant tracking system and working definitions for SARS-CoV-2 variants as part of our ongoing work to improve #COVID19 surveillance
1/9

who.int/news/item/15-0…
Omicron is the most genetically diverse variant of concern to date, and when it emerged was a game changer for the #COVID19 pandemic.
 
Since Feb 2022, Omicron and its many sublineages have almost completely replaced other variants. 2/9
. #Omicron viruses are now the background genetic pool from which new variants will most likely emerge. @WHO & TAG-VE will use the updated system to monitor #Omicron sublineages independently & consider their classification as variants of interest or concern, as needed.
3/9
Read 10 tweets
Mar 11, 2023
So where exactly are we now in the #COVID19 pandemic and where are we going?

Long thread ⬇️
@DrTedros @DrMikeRyan @WHO
3 years ago @WHO described the situation of #COVID19 as a pandemic, but it was 6 weeks earlier - on 30Jan20 - that @DrTedros declared the evolving situation as a Public Health Emergency of International Concern (PHEIC), our highest alarm to the world.

From 1 Jan 20 to that point, @WHO had issued EISs, DONs, comprehensive technical guidance, a global strategy to suppress transmission & save lives, sent officials to China to learn, started daily pressers warning the world to take action in the hope we could prevent a pandemic…
Read 24 tweets
Mar 2, 2023
🧵As an American myself and directly involved in the response to #COVID19 pandemic and in the origins studies since day 1, comments by @MarshaBlackburn, @SenatorRisch and others about @WHO and our work are deeply hurtful and inaccurate.
As the #COVID19 health operations & technical lead, my role has been to convene the world's expertise & consolidate that knowledge into actions that save lives. As the responsible technical officer for advancing our understanding of this current pandemic to prevent future ones…
I am deeply frustrated at the lack of additional information from the US reports assessing #COVID19 origins, which have not been shared with us and from investigations in China that can actually further the technical, serious discussions.
Read 5 tweets

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