0bFuSc8 Profile picture
Apr 23 8 tweets 3 min read Read on X
More info (some concerning) on our ongoing, multi-state #H5N1 outbreak in dairy cattle from the always thorough & informative @sciencecohen:


#HPAI
1/science.org/content/articl…
🚨 Concerning 🚨 – Vets relay anecdotes of dairy workers w/flu-like Sx who don’t not want to be tested or seen by docs.

I’m guessing there’s been a lack of clear communication w/these workers (often migrants, non-English speaking or undocumented)

@RickABright #H5N1 #HPAI
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Wastewater analysis (ongoing & retrospective) can help add info 👆, would be cost effective & should be relatively straightforward for @CDCgov to implement, as @RickABright has been saying.

#H5N1 #HPAI
3/
🚨 Also concerning 🚨 – Birds tested +ive for the 3.13 strain of #H5N1 & were culled at a MN turkey farm right next to a dairy farm that **refused to test** its cattle.

@RickABright #H5N1 #HPAI
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Apparently since USDA hasn't designated #H5N1 in cattle a “program disease” (even though it has in poultry), the fed government can’t cattle movement or require testing & reporting of infected herds or of the humans who work with them.

@RickABright #H5N1 #HPAI
5/
Necropsies on (some) infected dairy cows haven’t found #H5N1 virus in their respiratory tracts.

This, along w/large amount of #H5N1 virus being found in milk, supports direct spread via milk/ milking equipment.

#HPAI
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I appreciate USDA scientists are working hard, but the agency’s communications have been lacking —they haven’t been timely or transparent— and will impact credibility.

Mid/disinformation will flourish in an information vacuum.
#H5N1 #HPAI
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Good to *finally* get confirmation from FDA that they’re studying the impact of pasteurization (& other processes) on #H5N1 in milk, but this shouldn’t have taken nearly 1 mo into this multi-state outbreak.

Communication must get better, all around.

#HPAI
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More from @0bFuSc8

Apr 20
Good to see @CDCgov's #H5N1 update, but this isn't at all clear about (IMO much needed) surveillance in dairy farm/ other farm workers.

Epi field study/ site visit are good steps but likely not nimble enough to address the current situation.
#HPAI #AvianFlu
1/

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I rly hope the One Health Approach cited means more is in the works in terms of surveillance (in cows as well as humans), but IDK how much authority @CDCgov has at dairy farms.

@USDA @USDA_APHIS aren't recommending testing for asymptomatic cows and >>

#H5N1 #HPAI #AvianFlu
2/
And communication & genetic sequence submissions from @USDA have already been lacking.

Since this response has to be coordinated b/n multiple federal & state agencies, maybe it's time to create a coordinating task force?
#H5N1 #HPAI #AvianFlu
3/
Read 4 tweets
Apr 20
Promising news: per @nmpf's CSO, research is underway from @US_FDA & @USDA
to eval impact of pasteurization (& other processes) on #H5N1 #HPAI in milk:
(Thx @Alexander_Tin)

cc: @RickABright @HelenBranswell @thijskuiken @MarionKoopmans @KrutikaKuppalli
#AvianFlu
1/
Some more details here also on the clinical course of #H5N1 #HPAI in dairy cattle & timeline on farms:



cc: @RickABright @HelenBranswell @thijskuiken @MarionKoopmans @KrutikaKuppalli @EckerleIsabella
#AvianFlu
2/ tinalexander.github.io/notes/2024/04#…


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RE: Initial detection (took 6 or so weeks to ascertain this was #H5N1 #HPAI) & spread to herds in other states. -- (This wld put initial introduction late Jan/ early Feb)

cc: @RickABright @HelenBranswell @thijskuiken @MarionKoopmans @KrutikaKuppalli @EckerleIsabella
#AvianFlu
3/ Image
Read 5 tweets
Aug 21, 2022
@nicolamlow @angie_rasmussen Yup, the @PIDJournal report on the 2 cases exported to the UK is *much* more informative than that mess in @LancetRespirMed.

NOTE though, there have already been multiple reports from India that "tomato flu" is #HFMD (that the Lancet authors basically ignored) >>

1/
@nicolamlow @angie_rasmussen @PIDJournal @LancetRespirMed Health alerts in May from the districts in Kerala that were 1st affected already stated the colloquially termed "tomato flu" is #HFMD

thehindu.com/news/national/…

2/
@nicolamlow @angie_rasmussen @PIDJournal @LancetRespirMed When they started seeing cases in another state (Odisha) later in May, testing at Regional Medical Research Centre showed 26 of 36 samples +ive for Coxsackievirus, consistent w/#HFMD:

timesofindia.indiatimes.com/city/bhubanesw…

**Samples forwarded to @icmr_niv for sequencing w/results pending

3/
Read 5 tweets
Feb 14, 2020
14FEB (via @ChannelNewsAsia)
Singapore confirms 9 new #COVID19 cases, bringing the total to 67.

• 6 of the new cases are linked to the Grace of God Church cluster.

@KrutikaKuppalli @HelenBranswell @ScottGottliebMD @UNMC_DrKhan @MackayIM @V2019N



1/
@ChannelNewsAsia @KrutikaKuppalli @HelenBranswell @ScottGottliebMD @UNMC_DrKhan @MackayIM @V2019N 14FEB contd
• Grace of God Church cluster now has 13 cases

• Unclear if the other 3 new #COVID19 cases have known links to travel/transmission chain.
(Awaiting @sporeMOH report.)

• 6 (-1) cases remain in critical care/ICU

• 2 discharges (total recovered cases = 17)

2/
Read 9 tweets

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