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Christie Laura Grace Profile picture
@_HeartofGrace_
Aug 18, 2024 • 104 tweets • 53 min read • Read on X
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1/ A 🧵combining a bunch of 🧵s on cGAS STING and modRNA and LNP harms, including peer reviewed studies, specific injuries, with substack and podcast at the end.
"BREAKING STUDY PUBLISHED 10/17/2023: Foreign dsDNA can cause strokes via cGAS STING":

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2/ Length of the dsDNA plasmid drives strength of cGAs STING and the immune system. Cleaning it up and lowering amounts is a false statement.
Even in low amounts, longer pieces of dsDNA cause the most harm. 6/20
activatiohttps://x.com/_HeartofGrace_/status/1804274300255457685 Image
3/ T CELLS, have their OWN cGAS STING Pathway! DNA PLASMIDs can interact w/ cGAS STING OF T CELLS, causing FUNCTION of T CELLS to be: IMPAIRED, cause T CELL DEATH, IMPEDE T CELL PROLIFERATION, hindering an effective immune response, and CANCER.

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4/ STING Type III (R71H-G230A-R293Q) Common in European and Middle Eastern populations. this variation of STING has the highest prevalence of AUTOIMMUNE DYSFUNCTION AND AGRESSIVE CANCER RATES. Common in European and Middle Eastern populations.
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5/ A little map of injuries and image of a variation of STING and how that relates to mRNA NLP injuries

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6/ Another cGAS STING thread (this is not the spike protein)


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7/ CANCER: COMBINED" FEEDBACK LOOP of cGAS STING/ APOBEC: DNA plasmid in LNP +DS RNA triggers cGAS STING AND induction of DNA deaminase APOBEC3A + nuclear DNA damage: Dysregulation/feedback loops of cGAS STING meets APOBEC (DIFFERENT MULTI-HIT mechanism)

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8/ COVID JABS CAUSING MULTI SYSTEM ORGAN DAMAGE /FAILURE through (hyper) ACTIVATION/DYSREGULATION of cGAS STING pathway by interacting with DNA PLASMID contamination, SPIKE PROTEIN. (variants of STING and mutation of STING)

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9/ "Rapid Onset of Paralysis after COVID 19 Vaccination: potential cause: cGAS-STING "hyper" Activation a WITH INCREASED activation due to physiolgical differences in teenager compared to adult.
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10/
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11/ "p53 acts on the cGAS STING pathway in tumor suppression. cGAS STING has multiple roles in both driving cancer and stopping it."
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12/ There's a reason why hydroxychloroquine works with lupus and other autoimmune conditions (hydroxychloroquine works on the cGAS STING pathway).

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13/ "How plasmid DNA will track to the nucleus before it gets degraded in the cell. First it gets recognized by cGAS, ..., and actually PROTECT it from being broken down, and zip it right to the nucleus.:
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14/ cGAS STING DUOX2 and pancreatic cancer

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15/ berrant activation of cGAS STING pathway can cause neurodegeneration, leading to Alzheimer's and other neurological disorders. This is a complex process, and aggregation of proteins with amyloid structures forming is part of this pathway process.
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16/ cGAs STING during fetal development of lens


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17/ activation of the cGAS-STING pathway by POLE mutation likely contributes to advantageous survival of endometrial cancer patients with POLE mutations, as cGAS-STING pathway is associated with anti-tumor activity via stimulation of inflammatory genes

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18/ "Here is a list of many types of cells that are tied to cGAS STING. cGAS STING can be activated by pieces of DNA plasmid that exists currently as contamination in the current mRNA covid vaccines that utilizes plasmids. "

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19/ Now we tie cGAS STING to GSK-3, and the implications of disease, especially, amyloid (no spike needed!)

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20/ Our previous study found an increased accumulation of cytosolic dsDNA and expression of cGAS and STING in FLSs and synovial tissues from patients with RA. In addition, a positive correlation between the cGAS immunoreactive score"

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21/ More cgas sting interactions (like manganese)
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22/ cGAS STING pathway (DNA plasmid contamination can do this) activation and implications for prognosis, immune infiltration, and tumor metastasis in implications for prognosis, immune infiltration, and tumor metastasis

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23/ Lyme's disease and cgas sting (know anyone getting paid to do a study on this?

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24/ Brain injury, including seizures and strokes, have been recently found in studies this past year, to have involvement in activation by the cGAS STING pathway.

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25/ cGAS STING, dead box and cancer


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26/ I did this all to get sh1t on and used for a year, especially by people who pretended to be my friend and said they would help my dad. Scientists in THESE circles. Nice people.

cGAs STING injury and kidney injury link x.com/search?lang=en…
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27/ Pulmonary tumor after vaccination. cGAs STING and the lung

x.com/search?lang=en…
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28/ cGAS STING pathway: there are four different types of STING--This is dependent on race. European and Middle Eastern race share one distinct form. Africans another. Asians. And the indigenous. And within this pathway mutations exist.


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29/ impacts of the cGAS STING pathway activation with increased inflammation in hearing loss and tinnitus. The activation of the cGAS STING pathway by way of DNA plasmid contamination and the spike protein in Pfizer and Moderna MRNA vaccines...
x.com/search?lang=en…
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30/ cGAs STINg and carcinoma

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31/ cGAS STING, RA, and mod RNA injuries


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32/ cGAs STING T Cell Lymphoma after covid injection

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33/ cGAs STINg Alzheimer's


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34/ "GAS STING engages in what is called a 2:2 binding stoichiometry with DNA... two cGAS molecules bind to two DNA molecules. This is crucial for the activation of cGAS, leading to the production of cGAMP, which subsequently activates the STING

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35/ around 40 bp can still activate cGAs STING, two strands of it. That is it

No volume needed


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36/ ANCA-Associated Vasculitis after Moderna COVID-19 Vaccination (case report):
cGAS STING

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37/
How Chronic inflammatory demyelinating polyneuropathy (CIDP) is caused by cGAS STING pathway interactions--Case Studies: patients experiencing AIDP after AstraZeneca COVID vaccine.


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38/ Covid injections can cause virus reactivation, by the cGAS STING pathway. cGAS STING pathway can be activated by: DNA plasmid contamination, the spike protein, bacteria, and positive charges in the covid vaccines.


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39/ manganese activates cGAS STINg, and researchers want to add it to LNP platform

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40/ f it hasn't become painfully clear yet, one would think it is imperative regardless of situation, to do everything possible, to keep inflammation down in the body, and to not trigger the cGAS STING pathway. Repeated activation of this pathway is tied cancer. The activation itself causes genomic instability and mutations.

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41/ Cerebral venous thrombosis after COVID-19 vaccines


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42/ Role of cGAS STINg in tumor environment


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43/ cgas sting, and tumor evasion without integration


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44/ DNA Plasmid/Spike activate cGAS STING pathway, and cause progression of Adenomyosis, and other harms. (STUDY):


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45/ not only did hydroxychloroquine interfere with the ACE2 receptor according to studies, HCQ and CQ block the binding of dsDNA (should do the same with spike) to cGAS, thus attenuating the underlying activation of the STING pathway mediated by cGAMP

46/ cGAS STING Path and Genetics Edition. TL;DR: Variations in cGAS STING pathway, immune system, hormones, and genes—XX versus XY--are the reasons.

47/cgas sting again at the molecular level
48/ The cGAS-STING pathway promotes the development of preeclampsia, in pregnancy, which is dangerous to the mother and baby. Preeclampsia can impair fetal growth, decreasing supply of oxygen and can lead to preterm birth, stillbirth, or infant death. DNA plasmid pieces and spike protein can activate the cGAS STING pathway.
49/ cGAS STING Pathway Activation in the BRAIN: "cGAS/STING signaling pathway-mediated microglial activation in the PFC underlies chronic ethanol exposure-induced anxiety-like behaviors in mice"


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50/ High cGAS and STING expression was associated with a higher incidence of NRAS/KRAS mutations, which are linked to poor prognosis in several cancers.


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51/ The Role of cGAS-STING Signalling in Metabolic Diseases: from Signalling Networks to Targeted Intervention"


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52/ NO SV40 NEEDED! WHAT about MODERNA? Exactly! HMMM? There is no sv40 there. Been posting about cGAS STING since last October causing Aortic dissection, myocarditis, autoimmune, and cancer involvement.
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53/ mRNA "vaccines" contain DNA plasmid, and spike protein, which can activate a pathway--cGAS STING, and drive ONCOGENE EXPRESSION and MUTATIONS W/OUT SV40!! "cGAS-STING pathway expression correlates with genomic instability and immune cell infiltration in BREAST CANCER"

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54/ countless hours, making these threads.
If I counted them up I would probably, i dont know what

GAS STING, IS the unifying mechanism for "vaccine" injury, not just for autoimmune and cancer, but CLOTS too! Platelets and Megakaryocytes have cGAS STING activation for CLOT formation!

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55/
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56/
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57/

PHYSICAL LAB TEST ASSAY: HOW to TEST the VACCINE INJURED and THOSE who have DIED from VACCINE INJURY if cGAS STING was part of the INJURY due to SPIKE protein, DNA PLASMID PIECES ETC from AUTOIMMUNE ATTACK resulting in MYOCARDITIS, Aortic Dissection, mulit organ system failure, Cancer progression at TUMOR SITE, AutoImmmune Neuropathy, AIDP, SFN, and more: BELLBROOK LABS Transcreener cGAMP cGAS Assay directly measures cyclic GMP-AMP (cGAMP) produced by cyclic GMP-AMP synthetase (cGAS, C6orf150, 2'3'-cGAMP Synthetase). These cGAMP measurements allow researchers to effectively determine the enzyme's activity.Image
58/ Layman's terms: The cGAS STING pathway is a very complex system in our bodies that protects us from infection. It is also a part of autoimmune disorders, neurodegeneration, organ injury and failure, myocarditis, AAD, and CANCER.


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59/ Protocol to induce and assess cGAS-STING pathway activation in vitro" Perhaps some of the scientists who are doing tests on the vaccine injured, or those who have died from injuries, due to multi organ failure, myocarditis, aortic dissection, auto immune attack on any organ, on the nerves, on the brain

some people are disgusting, immoral, liars, and thieves

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60/
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61/ MYOCARDITIS: Inflammation and damage to the heart by DNA plasmid contamination and spike--activation of the cGAS STING pathway causes damage including MYOCARDITIS after COVID "VACCINATION" Transfection of the cardiomyocyte (layman's explanation at the end)
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62/ GUT MICROBIOME, and COVID: The microbiota in your gut is responsible for peripheral cGAS-STING activation, promoting resistance to systemic viral infections like COVID. If you give an antibiotic during a viral infection, you risk inactivation of cGAS STING to deal with that viral infection, systemically. Your gut microbiome is not some lone ranger just hanging out. Drinking, smoking, AND specific antibiotic use, will knock down numbers of bifidobacteria (some antibiotics, even one course will reduce for A YEAR).

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63/ There's a lot of talk right now about P53 and cancer. This is a lot of science for 4 AM. P53 degrades DNA exonuclease TREX1 via TRIM24, causing cytosolic dsDNA accumulation thus, triggering cGAS STING. Loss of cGAS STNIG activation means loss of tumor suppression. Right now, there is a small molecule that should hit the market (probably in three years give or take), that has nothing to do with a gene, that goes right in, and acts on STING, regressing colon cancer tumors from 70-90%.
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64/ cGAS STING is the primary pathway for many of the harms caused by the 💉 (outside of the genomic integration concern)


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65/ cGAS STING!!!


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66/ GAS STING Pathway Activation by DNA Plasmid Contamination, SPIKE, and LPS in modRNA "vaccines": AIDP, Myocarditis, Stroke, Aortic Dissection, and More: Overview, and Biopsy Methods for Detection. When DNA integration testing fails to produce results, this pathway, should.

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67/ All the same pathway--myocarditis, stroke, rapid aortic dissection, neurodegenration, autoimmune demylenating polyneuropathy, fbirosis, RA, IBD, and other disorders: cGAS STING pathway. The DNA plasmid contamination and SPIKE can activate and send into a feedback loop. Image
68/ Super stack on how a positive feedback loop is generated by the 💉: cGAS STING Pathway activation by DNA Plasmid Contamination, SPIKE, and LPS in modRNA "vaccines": AIDP, Myocarditis, Stroke, Aortic Dissection, and More: Overview, and Biopsy Methods for Detection.
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69/

MEGA THREAD ON MULTIPLE PATHWAYS AFFECTED BY DNA PLASMID CONTAMINATION that exists as a CpG motif, and potential negative health outcomes, depending on exposure (dose amounts unknown/duration/frequency. cGAs STING included


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67/ Recognition of DNA by cGAS is dependent on DNA length. Double-stranded DNA (dsDNA) longer than 20 bp activates cGAS, inducing dimerization of cGAS and resulting in the formation of a 2:2 DNA/cGAS complex, whereas dsDNA less than 20 bp is not able to induce cGAS dimerization and activation"

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68/ Inhibition of cGAS in Paraventricular Nucleus Attenuates Hypertensive Heart Injury Via Regulating Microglial Autophagy" The cGAS STING pathway is activated by exogenous (from the outside) ds(double stranded) DNA.


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69/ going back to the new year time. Well before Valentines day anyways

treacherous


Autoimmune diseases can be triggered by abnormal activation of the cGAS STING pathway. There are options to inhibit the cGAS STING pathway. The cGAS STING pathway is activated by exogenous DNA. Plasmid DNA contamination in RNA "vaccines" is, considered to our cells, to be exogenous (from the outside) DNA. "Meloxicam inhibits STING phosphorylation and alleviates intracellular DNA-mediated autoimmune responses"Image
70/ nhibition of cGAS in Paraventricular Nucleus Attenuates Hypertensive Heart Injury Via Regulating Microglial Autophagy" The cGAS STING pathway is activated by exogenous (from the outside) ds(double stranded) DNA. DNA plasmid contamination is exogenous DNA.

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71/ Activin A alleviates neuronal injury through inhibiting cGAS-STING-mediated autophagy in mice with ischemic stroke dsDNA is exogenous DNA. Plasmid DNA contamination in covid RNA vaccines is exogenous DNA. Exogenous DNA activates the cGAS STING pathway in cells.

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72/ cGAS inhibition alleviates Alu RNA-induced immune responses and cytotoxicity in retinal pigmented epithelium"

degusting pigs


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73/ Inhibition of the cGAS-STING Pathway Attenuates Lung Ischemia/Reperfusion Injury via Regulating Endoplasmic Reticulum Stress in Alveolar Epithelial Type II Cells of Rats


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74/ nhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration"


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75/ Inhibition of cGAS–STING pathway alleviates neuroinflammation-induced retinal ganglion cell death after ischemia/reperfusion injury"


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76/
There is a clinical trial on cGAS STING with IBS in kids correlating exogenous DNA--right now. cGAS STING pathway activation by pieces of DNA that do not belong, Maybe for vaxx injured, target it as last resort?



dont you wish you could go back in time, and never ever interact or cross paths with some people, ever?

me tooImage
77/A lso, zeta potential with its impact on biodistribution, the specific molar ratio required to transfect the cardiomyocyte, the charge causing clots, remodeling the inside of the blood vessels, and the DNA plasmid causing activation of cGAS STING pathway and it's impact on so many organ systems, not to mention the cancer implications and how it satisfies the muti hit cancer theory, progressing cancer

78/ Spike protein activates the Sting pathway.


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79/

dna/rna hybrids, dna plasmid, spike, ssDNA and dsDNA, and some other things activate cGAS STING

Activation of cGAS-STING Pathway Is Associated with MSI-H Stage IV Colorectal Cancer (dsDNA activates the cGAS-STING. Plasmid DNA IS dsDNA)


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80/ Nerve pain, chronic peripheral neuropathic pain, chronic central neuropathic pain, and inflammation can be caused by exogenous dsDNA interacting with the cGAS-STING pathway, resulting in a chain reaction. Plasmid DNA contamination in the RNA vaccines IS dsDNA.

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81/ Happy new Year. Time to jump right in. Do or do not--there is no try. For the science folks: Read these two in tandem: 1: "Innate Immune Response to Cytoplasmic DNA: Mechanisms and Diseases" "Suppression of cGAS Activity" "Suppression of MITA Activity"



they all ignored this, including AMLOST everyone in these circles, with an exception of people who knew this was true, including a politician

two of the of the scientists even went on podcasts who knew of everything I was posting, called giradot an LNP expert, who are currently writing papers. about cgas sting while gutting me again, while another let them drag me, and watched with glee

What great peopleImage
82/ CLNICAL TRIALS ARE IN PROCESS ON THE HARMS OF EXOGENOUS DNA ON CHILDREN! "Exploration of the Activity of DNA Located Outside of Cellular Nucleus to Amplify Inflammation in Inflammatory Bowel Disease in Children Through Biological Pathway Cyclic GMP-AMP Synthase (cGAS)

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83/ dsDNA in💉activates "STING", and may cause: Subarachnoid haemorrhage, Hypoxia, injure mitochondria, neurodegeneration, MS, Lupus, ALS, PRION disease, brain cancer, AGS, SAVI, chronic neuroinflammation, increased tumor growth, impaired T-lymphocyte, and more.
Dec 2023
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84/ more cGAS STING


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85/ Background on cGAS–STING Pathway: Cancer cells contain high levels of cytosolic DNA. The cGAS–STING signaling axis is a major sensor of cytosolic DNA and triggers the innate immune response, leading to the production of pro-inflammatory cytokines, including type I interferons.

dec 5 Image
86/
December, 2023
Thyroid damage and auto immune is linked to dsDNA. dsDNA is found in the current plasmid DNA contamination. This is slightly different in the thyroid ( histone H2B)


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87/ Nov 26, 2023

cGAS STING pathway is activated by ds DNA ( plasmids) in cells (outside nucleus). It is complicated, and interacts with helicases, like DEAD box (DDX#) Proteins. Dysregulation in cGAS-STING pathway, like DDX41, can lead to tumor formation (cancer). cGAS STING can be mutated

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88/ DEAD BOX ! Dead box! and cGAS STING!

cGAS STING pathway is activated by ds DNA ( plasmids) in cells (outside nucleus). It is complicated, and interacts with helicases, like DEAD box (DDX#) Proteins. Dysregulation in cGAS-STING pathway, like DDX41, can lead to tumor formation (cancer). cGAS STING can be mutated


These same scientists, doc, etc told me I did not know what I was talking about here either.

THIS delayed science, actually delayed trying to warn people, by dragging me through the mud while focusing on sv40 and defamed me. I think some people do not owe just ME an apology, but to apologize to others for covering me up, slandering me, defaming me, and dragging me through the mud for over a year, it meant this info was sh1t on while they sh1t on me. How terrible!

Think about that
What great people.Image
89/his study comes in handy. The cGAS-STING pathway "sees" aberrant nucleic acids. The DNA plasmids are already aberrant in more than one way--it's bacterial, recombinant, has CpG motifs, AND, according to the study breakdown in the thread below, is being mutated inside the LNP!

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90/
The cGAS-STING pathway in humans, can detect and be activated by pieces of DNA, bacterial DNA, AND RNA (all are in the LNP!) If activated (which is outside of the nucleus), this can lead to multiple diseases, including autoimmune disease and cancer.


When these people sh1t on me, they sh1t on everything I was posting here, with malicious intent.
While people kept getting harmed, while articles were written about green monkey DNA.
Think about thatImage
91/
They all ignored it while people kept getting harmed.
DNA contamination found in c@vid vaccines IS dsDNA. Humans have a pathway called, cGAS–STING pathway. This pathway can be activated by dsDNA (PLASMID DNA), causing autoinflammatory, autoimmune, degenerative disease, and cancer.

we are now into november, 2023. The only thing being discussed was SV40 and DNA plasmids. Think about this.. dragged through media channels while people were harmed and died. I have no good words here.



What great people.Image
92/Npv 15 2023
DNA PLASMID CONTAMINATION in mod RNA "vaccines" does NOT have to enter the nucleus to cause cancer. Recent advances have now expanded the roles of cGAS-STING to cancer. Highly aggressive, unstable tumors have evolved to co-opt this program to drive tumorigenic behaviors. "The cytosolic DNA-sensing cGAS-STING pathway in cancer": can be activated by dsDNA outside of the nucleus, which can be in the form of DNA plasmid contamination, which was recently found by multiple scientists in the c@vid "vaccines", thus, causing aggressive, unstable cancer.

I was told I did not now what i was talking about, by scientists i these circles, and that I was a piece of sh1t

By doing this, that buried everything I was talking about, for a YEAR, all for the pleasure of beating someone up online

what great people

93/ oo. SAME PATHWAY (cGAS) Acute myocardial infarction is accompanied by massive cardiomyocyte necrosis and tissue inflammation. In multiple studies, it was reported this extensive cardiomyocyte necrosis is also associated with elevated circulating mtDNA

Right there. November 2023--I talked about mtDNA and myocarditis

94/
nov 15 2023


DNA PLASMID CONTAMINATION in modRNA vaccines can cause STROKES Same pathway as CANCER. IT does NOT need to enter the nucleus. cGAS-STING pathway is mediator in response to dsDNA. DNA plasmid contamination is dsDNA.

(I was told everything that was said by CR. Receipts)Image
95/ dsDNA [PLASMID CONTAMINATION IN LNP/modRNA ] CAN CAUSE STROKES via cGAS STING


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96/ rumble cgas sting (I was supposed to record something similar MONTHS ago but my friend /podcaster had a baby, which is more important,

rumble.com/v58fgjp-the-pa…
97/ cGAS STING Pathway activation by DNA Plasmid Contamination, SPIKE, and LPS in modRNA "vaccines": AIDP, Myocarditis, Stroke, Aortic Dissection, and More: Overview, and Biopsy Methods for Detection.

christiegrace.substack.com/p/cgas-sting-p…
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98/ CANCER: "COMBINED" FEEDBACK LOOP of cGAS STING AND APOBEC: DNA plasmid in LNP +DS RNA triggers cGAS STING AND induction of DNA deaminase APOBEC3A + nuclear DNA damage:

christiegrace.substack.com/p/cancer-combi…
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99/ Hydroxychloroquine! But, it's not just antiviral. Look what it is doing to cGAS!


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100/ this actually occurs via cgas sting, apobec, a couple of other things, and one mechanism I a waiting to finish writing and submit on.


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More from @_HeartofGrace_

Christie Laura Grace Profile picture
Mar 26
🚨💉🦠PREPRINT! Journal has it now. NEW theoretical MULTI AXIS MECHANSM by spike protein, SHARED DISEASE and worse between LONG C@VID and C@VID V@CCINATION via ion channel dysfunction, and AUTO ANTIBODIES TO THE PROTEINS OF THE SODIUM CHANNEL!
Short summary below👇

THIS IS THE SHARED THEORETICAL MECHANISM:

I am about to release two more papers to preprint and journals in next 24 hours on worse symptoms, clots, and cancer.

I cannot write the summary I wanted, I have to go back to writing. This is al I got.
I must get back to writing, and sleep sometime.

✅Ion channels are tiny gateways in our cells that control how ions (like sodium, potassium, and calcium) move in and out. This

is crucial for sending signals in our nerves, regulating our immune system, and keeping our cells functioning properly.

This spans ALL of our physiological processes--ALL CELLS.

When ion channels don’t work correctly— ion channel dysfunction can cause a wide range of health issues, including neurological disorders, chronic pain, and immune system problems. Mast cell. So many things--head to toe. Not just nerve symptoms. All symptoms. Clots, All of it. Vascular permeability. All of it.

I am completing deeper dive on this because there just was not enough room in the paper to do it--exact further mechanisms on organ injury and cancer. This includes but not limited to myocarditis and organ injury. Antibodies against the areas and more with dysfunction of the ion channels in tandem with cGAS STING, MACROPHAGE, ZETA PPOTENTIAL, HORMONES, GENETIC MUTAIONS, PAMPS and DAMPS, and more.

Both C@VID-19 infection and v@ccination MIGHT, theoretically, contribute to ion channel dysfunction through immune system overactivation, chronic inflammation, and the production of autoantibodies that mistakenly attack ion channels.

The cGAS-STING pathway, which detects viral threats, can become overactivated, leading to persistent inflammation and autoimmune reactions. Additionally, the spike protein from SARS-CoV-2 shares structural similarities with certain ion channel proteins, which may lead the immune system to mistakenly target these channels, causing transient or chronic dysfunction. In some cases, this immune response may be self-limiting, resolving over time, while in others, it may lead to long-term autoantibody production, resulting in sustained neurological, cardiovascular, and muscular symptoms.

cGAS AMPLIFIES the feedback loops, while macrophages get dysregulated in the consumption of the charged lipids, the vessels in capillaries and arteries become permeable, clots--next paper in 24 hours will show full on mechanisms--tissue damage. The eyes, the whole body. Brain. IN SOME PEOPLE.

Can cause people to have all kinds of things getting misdiagnosed or as secondary effects. Bed bound. Death

This could if, THEORETICALLY, with severe gain of function mutations present in ion channel encoding for proteins in ion channel, cause cascade of immune system, autoantibody attack against proteins of ion channel, appear sepsis like, and cause death.

Heart attack.. SIDS. Sudden adult death.

FOR WOMEN--this paper shows that estrogen has an impact on ION CHANNELS and how that if a woman is menstruating and still has estrogen present, each month, a flare may occur, and cause worsening autoimmunity, which is not to say men have not suffered, but why WOMEN are suffering from these symptoms MORE. Could be worse all the time. Immune reaction worse. Initial injury worse.

Also, WHITE EURPOEANS and middle eastern background compared to African, Asia, and indigenous, while still suffering harms, have higher levels of STING activation due to variation in STING pathway making more susceptible to dysregulation, meaning more autoimmunity and harms than others in white and middle eastern background.

ALSO--women have dysregulation in gut brain axis due to estrogen.

Due to their role in nerve signaling, muscle function, immune regulation, and cardiovascular stability, dysfunctional ion channels can lead to widespread symptoms, including
SFN LIKE symptoms, AIDP LIKE symptoms. GBS like symptoms, transverse myelitis,
tachycardia, bradycardia, palpitations, arrhythmias, hypotension, hypertension, dizziness, fainting, syncope, chest pain, blood pooling in the legs, poor circulation, orthostatic intolerance, POTS-like symptoms, brain fog, migraines, chronic headaches, vertigo, tingling, numbness, neuropathy, tremors, muscle weakness, myoclonus, ataxia, seizures, hypersensitivity to light and sound, temperature dysregulation, fatigue, autonomic dysfunction, memory problems, difficulty concentrating, muscle cramps, muscle spasms, muscle stiffness, twitching, myopathy, exercise intolerance, paralysis episodes, myalgia, difficulty swallowing, loss of fine motor control, nausea, vomiting, bloating, diarrhea, constipation, gastroparesis, IBS, abdominal pain, acid reflux, swallowing difficulties, shortness of breath, hunger, hyperventilation, irregular breathing, chest tightness, chronic cough, respiratory muscle weakness, hormonal imbalances, ovarian dysfunction, irregular periods, amenorrhea, infertility, PCOS, thyroid dysfunction, insulin resistance, unexplained weight loss or gain, frequent urination, bladder dysfunction, incontinence, difficulty urinating, interstitial cystitis, kidney dysfunction, chronic inflammation, autoimmune disease, increased susceptibility to infections, mast cell activation syndrome, histamine intolerance, allergies, skin rashes, hives, anxiety, panic attacks, depression, mood swings, irritability, insomnia, hypersomnia, depersonalization, derealization, heat intolerance, cold intolerance, excessive sweating, lack of sweating, lightheadedness, vision disturbances, difficulty adjusting to light changes, tinnitus, and sensitivity to sound, smell, or touch.

This is NOT the complete list!

Organ injury, hypo or hyper thyroid like symptoms--that whole list on the Pfizer data dump: run through them. Specific ion channels are 4--also acetylcholine channel.

The cGAS-STING pathway detects foreign or self damaged DNA inside cells, triggering an immune response.

When SARS-CoV-2 infects cells or lingers as viral remnants, it can overactivate, leading to prolonged immune responses that may mistakenly target self-proteins, including ion channels. This process can contribute to autoantibody formation against ion channels, which may explain persistent symptoms following COVID-19 infection or, in rare cases, vaccination. THIS is combined with macrophage polarization and spike protein on ion channels-theoretical.

Because the spike protein shares structural similarities with certain ion channels, the immune system may temporarily mistake ion channels for the virus, leading to transient dysfunction. In some cases, once the immune system resets, symptoms resolve. However, in other individuals, this misdirected immune response is chronic, leading to persistent autoimmune-mediated ion channel dysfunction.

This could explain why some individuals experience long-term neurological, cardiovascular, or muscular issues after infection or vaccination.

This does not say that sv40 and biotech plasmids with other properties of spike are not present. This paper could not address that and does not discount.

Add in dna plasmids amplifying cgas sting and macrophage and charged lipids impacting further, and recipe for disaster.

The possibility of transient versus chronic ion channel dysfunction due to cGAS-STING activation and autoantibodies is URGENT need for testing for ion channel autoantibodies in individuals experiencing post-COVID or post-vaccine symptoms.

Identifying these autoantibodies could lead to better-targeted treatments, distinguishing between cases that may resolve over time versus those requiring immunotherapy. Research into the mechanisms behind autoimmune ion channel dysfunction will be crucial for improving diagnosis and treatment options for those affected by these complex conditions.

There is current drugs present that cost under ten dollars for ion channel dysfunction like tegretol. I am not a medical doc and this is not treating or DXing anything. Always check with your doc.

People are suffering spread the word. This is theoretical.

For those with labs, get testing!!!!

I have to go now and write.
I am ONLY answering emails and calls right now form doctors I am arranging meetings with. If you have questions, ask the experts in your circles.

I cannot chat about this or answer questions. If you want summaries, load into grok or whatever you choose. I must go.

I have work to do and messaging slows me down.Image
2/ The cGAS-STING Pathway, Ion Channel Dysregulation, and Immune Responses: Implications for Autoimmunity, Inflammation, Long COVID, and Post-Vaccination Responses

osf.io/preprints/osf/…Image
@drdrew
@DrJBhattacharya
@drjamesbjoyce
@mottomeneki
@DrTeckKhong
@JohnBoweActor
@DiedSuddenly_
@SenatorRennick
@FLSurgeonGen
@TuckerCarlson
@RobertKennedyJr
@NicoleShanahan

People told me to wait-I cannot. I am writing fast and two more are coming in 48 hours.
@RepThomasMassie

@TheChiefNerd

@EthicalSkeptic

@Signal2Noise4

@Pinzie
Read 12 tweets
Christie Laura Grace Profile picture
Feb 24
1/ 🚨💉🧬 Hot off the presses, March 2025, almost one year later, "next gen mRNA"

"CpG ODN-adjuvanted, alum-adsorbed, virus-like particle (VLP) vaccine displaying the hexaproline stabilized Spike (S) protein and the Nucleocapsid, Membrane, and Envelope proteins of SARS-CoV-2." Image
2/

(This requires access, so I will screen shot) sciencedirect.com/science/articl…Image
3/ The sentence reads like a nightmare to me: " CpG ODN-adjuvanted, alum-adsorbed, virus-like particle (VLP) vaccine displaying the hexaproline stabilized Spike (S) protein and the Nucleocapsid, Membrane, and Envelope proteins of SARS-CoV-2."
Read 29 tweets
Christie Laura Grace Profile picture
Feb 23
The material that has gone into humans is research grade at best. That means RG. Fit for animals but not humans.
I dare say it was even fit for animals.

I know because it was my job.

I know the difference between research grade, cGMP (which still has its issues, One just need to research any 483 form with the FDA, or having worked designing the stuff).

I designed recombinant proteins custom, fusion proteins with specialty RNA, lipids, custom work for those who have suffered from genetic disease and cancer.

Those are small batches for clinical trials that are highly filtered by expert teams with all eyes on every vial, clean as can be, with small cohorts of maybe a few dozen people, and a liter of material. And with all that, there is still side effects because that platform is flawed on multiple levels. I can cite study after study right now on the reasons why it that is, and to pull them all from my profile, and so could others.

Sludge was allowed to be injected into over 5 billion people.

Non-coding RNA can cause cancer. Fact.

Multiple studies including done by experts who out rank anyone here in the US or the UK over in Korea have done the tests stating that the modified RNA is breaking inside the LNP. This renders it non coding, which means it can't make anything and it's only function is going to be to interfere with other cellular mechanisms with the concern of causing cancer. It can cause transient concerns which can activate pathways regardless if it is degraded in the cells.

The lipids themselves have been used in multiple studies injected into animals and have been found to cause disease and cancer because of the disruption of the continual injection and what damage has occurred as a result of exhaustion of the mononuclear phagocyte system. That's something you are not familiar with and what I'm stating here is not known to most people reading this.

Positively charged lipids have an impact on cellular function and if they aggregate an areas they can do damage.

The modified RNA has been shown to have oncogenic properties.

This modified RNA also has been known to frame shift inside the ribosome causing junk proteins to be made which is irrelevant because....

Moderna did their own study with their own researchers only a couple of years ago which they paid for using special equipment and they found (packer et Al 2021) that the impurities in the positively charged lipids are covalently bonding to any nucleic acid they come in contact with including the modified RNA inside the lipid nanoparticle creating what is called an adduct and it is occurring in about 10 spots per piece of RNA in each of the particles which, will cause the same issue and cause the slippage in the ribosome causing non-coding issues which means we're back to the cancer possibility with the junk protein being made with aggregation and misfold of a spike protein that is already known to have amyloid properties related to neurodegenerative disease.

The lipid nanoparticle itself contains high levels of the original starter biotech plasmid which was housed in e coli and grown up to make the modified RNA. On this piece of plasmid which is circular which you can look up anywhere, It contains multiple parts and the one moderna used is slightly different than the one Pfizer used. There is a spot for the protein gene of interest. I can show you a video of you would like and you are a smart guy and it was done by a biotechnology student. There's also an antibiotic resistant gene, And a few other sections and on the Pfizer plasmid there is what is called the SV40 promoter which is minus the large T antigen However is still a very strong promoter. The CMv promoter also a strong promoter.

These are circular and they were not digested properly or removed from any of the batches and it all went into humans.

The scale of harm that could theoretically be on deck is unlike anything our civilization has ever seen when it comes to the potential harms.

I've heard people say they don't want to scare people.

The amount of cancer and autoimmune around myself and others is staggering. People in their 30s at my clinic have cancer. People in their twenties. 17-year-olds with brain tumors. A 9-year-old boy just got taken to the children's hospital here a couple months ago with myocarditis right after... Guess what?

That promoter can have transient expression in ways I'm not typing here because I'm writing a paper on it and when it's shown exactly what it is doing in cells aside from its other activity and how it can interfere with the proteome, in ways that people are not currently checking which will take time and sales turn over and the proteome is going to start replacing and making adjustments and fusion proteins are going to start to occur in some people (if they aren't already.... Fusion protein is often present in lymphoma, piers).

Then we have the issue with biodistribution and they lied about the whole thing including studies that prove more than once with full data to back peer-reviewed that the particle itself has a different biodistribution in pregnant animals compared to non-pregnant animals that it goes to the lymph nodes 8 times more and that means everything is going to the lymph nodes eight times more including eight times the spike protein eight times the RNA 8 times the positively charged lipids eight times the DNA plasmid contamination and any other god-awful contamination that exists that we know about which is occurring often like bacteria and other plasmids and cross-contamination from other projects because it is a well-known fact that this occurs and any 483 will show you this in every other plant on the planet.

This thing was never going to save anyone.

This needs to be taken very seriously.
@piersmorgan PS

I ranted that all from my phone using voice to text. I apologize for any grammatical errors
1/ plasmid dna can be taken up by a lymphocytes when injected into the muscle.

That's the biotech plasmid.

In pregnant females this happens at eight times the volume regarding lipid nanoparticles going into their lymph nodes while they are experiencing changes in their immune system but it also goes to the placenta.

Typing from my phone here

x.com/_HeartofGrace_…
Read 35 tweets
Christie Laura Grace Profile picture
Jan 25
1/ Digital Twins and Cancer.
This has already begun.
There's talk about how this translates into the human, physical world. This has already begun with the use of what are called organoids, which Harvard was and others were investigating, before it gained traction. Image
2/ you can read here about the use of a digital twin and cancer.

. sciencedirect.com/science/articl…Image
3/ the use of organoids for customized, personalized cancer treatment is already happening, privately. You're just not hearing about it. In 2017, HARVARD researchers started using organoids. Image
Read 19 tweets
Christie Laura Grace Profile picture
Dec 31, 2024
1/ 🚨"35-year-old woman contracted Lou Gehrig's disease after her first Pfizer dose."
ACTIVATION of DORMANT GENES in BOTH ADENOVIRUS AND RNA BASED.
These "products" like adenovirus and RNA/DNA can be DORMANT (see linked thread) and then become ACTIVE. Not just cancer :(
READ👇 Image
2/ Charcot's disease is amyotrophic lateral sclerosis

'Charcot's Disease' is a progressive and fatal

progressive death of motor neurons

.ama-assn.org/delivering-car…
3/ "New-Onset Amyotrophic Lateral Sclerosis in a Patient who Received the J&J/Janssen COVID-19 Vaccine"

pmc.ncbi.nlm.nih.gov/articles/PMC10…
Read 26 tweets
Christie Laura Grace Profile picture
Dec 31, 2024
1/ 🚨 THEY KNEW.
"REACTIVATION" potential of ADENOVIRUS VECTORS used for "gene therapy", including the use of DNA PLASMID with LATENT and REACTIVATED STATES for BOTH and why this is important for SHEDDING and DISEASE.

🚨DATE of ISSUE: JANUARY 2020. COINCIDENCE? Image
2/ Pierre Kory and others have talked a lot about shedding--they are correct. The studies are on viral vectors--these are viral vectors. There are studies I have and so do others on this, but to drive it home--right here:

gillettechildrens.org/your-visit/pat…Image
3/ back to the first document: this was released 01/2020, right before the world was about to go into forced measures against the people, demanding they get injected with something that needs FIFTEEN YEARS of testing. The US had the gene sequence form CHINA in this moment. Image
Read 33 tweets

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