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Sanjay Mukhopadhyay Profile picture
@smlungpathguy
Sep 17, 2024 • 40 tweets • 11 min read • Read on X
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Inspired by all the pathologists' assistants I met at the @PathAssist annual conference, I'm starting a thread of educational #grosspath images

1. Thymoma (note white fibrous bands) Image
2. Laryngeal cancer (with key structures labeled) Image
3. Lymphangioma (transilluminated) Image
4. Mesothelioma (pleural) Image
5. Mesothelioma (extensive labeling of an extrapleural pneumonectomy) Image
6. Synovial sarcoma mimicking mesothelioma Image
7. Pseudomembranous colitis #gipath #pathology #grosspath @danielsode Image
@danielsode 8. Pulmonary sequestration (a portion of lung supplied by a systemic artery arising from the aorta) Image
Image
Image
Image
@danielsode @crimsonnyte 9. Metastatic melanoma within a lymph node Image
@danielsode @crimsonnyte 10. Renal cell carcinoma, from the #yalerosenslidecollection by @yro854 Image
@danielsode @crimsonnyte @yro854 11. Mesothelioma (with parietal pleura partially pulled off) Image
@danielsode @crimsonnyte @yro854 12. Schwannoma Image
@danielsode @crimsonnyte @yro854 13. Teratoma with teeth (Rokitansky protuberance) Image
@danielsode @crimsonnyte @yro854 14. Osteosarcoma Image
@danielsode @crimsonnyte @yro854 15. Coal workers' pneumoconiosis Image
@danielsode @crimsonnyte @yro854 16. Liver metastases from lung cancer (this is stage 4 cancer by definition)
@danielsode @crimsonnyte @yro854 17. Lung cancer in a lobectomy
@danielsode @crimsonnyte @yro854 18. Mesothelioma tracking into interlobar fissure and metastatic to lymph node
@danielsode @crimsonnyte @yro854 19. Invasive Aspergillus pneumonia vs mucinous adenocarcinoma. Read comments in the post to learn which one is which. Lung cancer can mimic pneumonia very closely!
@danielsode @crimsonnyte @yro854 20. Solitary fibrous tumor
@danielsode @crimsonnyte @yro854 21. Hepatic adenoma by my friend @DrjohninNE
@danielsode @crimsonnyte @yro854 @DrjohninNE 22. An example of great gross pathology teaching tips by @DraEosina
@danielsode @crimsonnyte @yro854 @DrjohninNE @DraEosina 23. Spermatocele, by the master of gross pathology photos @VijayPatho
@danielsode @crimsonnyte @yro854 @DrjohninNE @DraEosina @VijayPatho 24. Solid pseudopapillary neoplasm, pancreas
@danielsode @crimsonnyte @yro854 @DrjohninNE @DraEosina @VijayPatho 25. Gallstone by @StuffIGross
@danielsode @crimsonnyte @yro854 @DrjohninNE @DraEosina @VijayPatho @StuffIGross 26. 2 ureter kidney by @JMGardnerMD
@danielsode @crimsonnyte @yro854 @DrjohninNE @DraEosina @VijayPatho @StuffIGross @JMGardnerMD 27. Leiomyosarcoma by @JMcMahonG
@danielsode @crimsonnyte @yro854 @DrjohninNE @DraEosina @VijayPatho @StuffIGross @JMGardnerMD @JMcMahonG 28. Cryptococcoma, lung (@miguelguzmanmd )
@danielsode @crimsonnyte @yro854 @DrjohninNE @DraEosina @VijayPatho @StuffIGross @JMGardnerMD @JMcMahonG @miguelguzmanmd 29. Osteochondroma by @ThePAWearsPrada
@danielsode @crimsonnyte @yro854 @DrjohninNE @DraEosina @VijayPatho @StuffIGross @JMGardnerMD @JMcMahonG @miguelguzmanmd @ThePAWearsPrada 30. Cirrhosis by @MirunaPopescu13
@danielsode @crimsonnyte @yro854 @DrjohninNE @DraEosina @VijayPatho @StuffIGross @JMGardnerMD @JMcMahonG @miguelguzmanmd @ThePAWearsPrada @MirunaPopescu13 31. Another excellent guide to larynx specimens
@danielsode @crimsonnyte @yro854 @DrjohninNE @DraEosina @VijayPatho @StuffIGross @JMGardnerMD @JMcMahonG @miguelguzmanmd @ThePAWearsPrada @MirunaPopescu13 32. The most beautifully labeled pancreatic #grosspath images on X are by @PancPathologist
@danielsode @crimsonnyte @yro854 @DrjohninNE @DraEosina @VijayPatho @StuffIGross @JMGardnerMD @JMcMahonG @miguelguzmanmd @ThePAWearsPrada @MirunaPopescu13 @PancPathologist 33. I wish I had something like this to watch when I was starting off as a resident in #pathology but unfortunately there was no such thing in 1999! Beautifully done educational #grosspath video by @StuffIGross 🙏🏾 x.com/StuffIGross/st…
@danielsode @crimsonnyte @yro854 @DrjohninNE @DraEosina @VijayPatho @StuffIGross @JMGardnerMD @JMcMahonG @miguelguzmanmd @ThePAWearsPrada @MirunaPopescu13 @PancPathologist 34. Clear cell RCC by @_Wondweson64
@danielsode @crimsonnyte @yro854 @DrjohninNE @DraEosina @VijayPatho @StuffIGross @JMGardnerMD @JMcMahonG @miguelguzmanmd @ThePAWearsPrada @MirunaPopescu13 @PancPathologist @_Wondweson64 35. Uterus and endometrium by @StuffIGross
36. Metastatic melanoma by @rqbittenc
37. Miliary tuberculosis by @yro854
@yro854 38. More excellent placental pathology by @StuffIGross

Velamentous!
@yro854 @StuffIGross 39. More excellent #grosspath education by @StuffIGross
@yro854 @StuffIGross 40. @StuffIGross is amazing! #PathTweetAward

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More from @smlungpathguy

Sanjay Mukhopadhyay Profile picture
Dec 31, 2023
Last tweetorial of 2023 (@TristanRutland7 style again!)

Endobronchial biopsy, right lower lobe, elderly man

#pathology #pulmpath #pathtweetorial Image
What is the likely cause of these histologic findings?
Iron stain (Perls') Image
Read 15 tweets
Sanjay Mukhopadhyay Profile picture
Dec 2, 2023
Tweetorial in the style of @TristanRutland7

Lung nodule, adult

#pathology #pulmpath #PathTwitter #cytopath

Image
Image
Image
Based on the above, what is your initial thought?
Chromogranin Image
Read 19 tweets
Sanjay Mukhopadhyay Profile picture
Jan 18, 2022
1.
Multiple tweet thread #tweetorial on pathologic abnormalities in the lung caused by cigarette smoking

Smoking causes a wide variety of pathologic changes in the lung, not just lung cancer. Some of these are underrecognized or poorly named

#smokinglungpath #pulmpath
2.
These smoking-related abnormalities include:
💥 Emphysema
💥 Pigmented airspace macrophages
💥 Ropy interstitial fibrosis (SRIF)
💥 Pulmonary Langerhans cell histiocytosis

Overlap is common because these abnormalities commonly occur together.
3.
Every week I will add my thoughts to this #pathtweetorial . I feel strongly about this topic because I see SO much smoking-related lung pathology that is misinterpreted and underrecognized. Not just SRIF (👇🏾) but also pigmented macrophages, commonly dismissed as “anthracotic”
Read 10 tweets
Sanjay Mukhopadhyay Profile picture
Jan 16, 2022
1/4 (4-tweet thread)
A recent study in @ModernPathology
by Xie et el examined the ability of a deep convolutional neural network to diagnose which tumor in pleural effusions? #pathpolls
2/4
 Correct answer: lung adenocarcinoma.

nature.com/articles/s4137…
3/4
The authors claim the sensitivity and specificity of the deep convolutional neural network was somewhere between senior and junior cytopathologists. What were the numbers (sensitivity, specificity)?
cc: @DrNetto
Read 4 tweets
Sanjay Mukhopadhyay Profile picture
Mar 5, 2021
1/
 Announcing a contest to win a free pathology textbook!

Thanks to a brilliant idea by @DrMissWV and a generous offer by @science_press and @LizMontgomeryMD we are giving away a few free textbooks in an educational tweet contest called #pathbracket . See thread 👇🏾
2/
If you want to enter the contest, create a NEW educational pathology tweet between today and March 15 and tag it with #pathbracket

You must tag your own tweet. The tweet must have educational value. Tweetorials are allowed too. Contest is open to all.
3/
 On March 16, #PathTweetAward judges led by @DrGeeONE will donate their time to pick 32 of the best tweets to enter in a bracket similar to #MarchMadness . Credit with the idea of a bracket goes to @DrMissWV

Progression through the bracket will be on the basis of polls.
Read 6 tweets
Sanjay Mukhopadhyay Profile picture
Jun 7, 2020
1. How do we tell primary lung cancer from metastatic cancers from other sites?

It’s correct to say we should use all available clinical, radiologic and pathologic information, but that’s too vague to be helpful in a practical sense.

Here I offer some tips. #tweetorial
2. This #pathtweetorial is applicable mainly to #pulmpath . The principles in each organ are different. A carcinoma in a lymph node is a metastasis by definition. Not so in lung or colon.

IMHO it’s a mistake to approach a carcinoma in the lung as carcinoma of unknown primary
3. Most metastatic carcinomas to the lung occur after the primary carcinoma has already been diagnosed in another site.

💥Clinicians: give your pathologists this information! If you don’t, this is substandard, dangerous patient care.

Read 42 tweets

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