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☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆

@DrJackKruse

Mar 10

How did we get creativity? Neanderthals migrated North got to 51st latitude froze started wearing animal skins and used fire inside caves and their brains shrunk as a result. As they shrunk due to dehydrated melanin sheets, melanin becomes dopamine. The dopamine built up and we got art culture and DaVinci.

2. Note how melanin degrades on the slide on the top line. It degrades into dopamine, other amines, and L-DOPA. When you undergo a TBI, as the Neanderthals did by going too far up on the planet, it gets cold, and you need animal skins and fire to keep you warm. Why? Neanderthals did not have uncoupled haplotypes yet. That is a human innovation to high-latitude living. As a result, they flood their shrinking brain with more dopamine than they should have had. Voila = You eventually get Michealangelo, DaVinci, and Rembrandt.

3. Look at the picture.

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☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆

@DrJackKruse

Mar 9

https://twitter.com/CaliCajun111/status/1898769296144347528

The Birkeland currents in space directly scale to the bioelectric currents and electric resistance on our membranes in a cell, so yes this post is spot on.

https://twitter.com/CaliCajun111/status/1898769296144347528

2. As Chris points out, Birkeland Currents are observed in Earth’s magnetosphere (e.g., 10⁵-10⁶ amperes), these currents are driven by magnetic reconnection, a process scalable to cellular ion channels. No direct studies link them to bioelectric currents yet but maybe @MitoPsychoBio or Levin will consider testing this as Becker did with Brown in the UK, but fractal models (e.g., 2022 Physical Review Letters) suggest universal energy flow principles because these are laws of nature not subject to belief.

Space Weather and Health: A 2023 study in Scientific Reports correlated geomagnetic storms with increased hospital admissions for mental health issues, supporting the bipolar disorder claim. Anthropogenic nnEMF (e.g., 5G at 3.5 GHz) is understudied, with the WHO citing insufficient evidence of harm, possibly due to industry influence.

Melanin and Bioelectricity: Becker’s work showed melanin conducts currents (e.g., 10⁻⁶ A/cm² in salamanders), disrupted by dehydration, aligning with my ideas here. Sunlight’s role in melanin hydration lacks large-scale data but fits the physics that underpins chronobiological evidence.

3. Implications and Decentralized Synthesis

Resistance and Energy Flow: Chris's post’s focused on resistance scaling from space connecting to cells mirrors Picard/Levin ideas in their éR framework, where mitochondrial efficiency (steps 7-9 in pic) depends on bioelectric balance, disrupted by blue light, nnEMF, and deuterium.

Therapeutic Potential: Methylene Blue’s stabilization of éR when the IMM has low delta psi, combined with sunlight and grounding, mitigate these effects, enhancing regeneration currents and reducing in many diseases like neurodegeneration risks in CTE or MS.

Societal Impact: My link to cognitive decline from poor light choices extends to Chris's post cosmic-biological narrative, suggesting environmental factors shape societal decision-making. This is certainly true in stock markets and in discussions on social media where chaos exists.

Critical View: The centralized establishment’s resistance to these ideas may stem from a lack of biophysical mechanistic studies and a preference for molecular over bioelectric models. Interdisciplinary research is needed to validate this scaling hypothesis. This is where Picard and Levin have to put their big boy pants on and get to physics. My world ;).

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☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆

@DrJackKruse

Mar 9

1. The world is an energy vampire built by technocrats/DARPA to drain the brain of energy to propel us to proper actions We can see this blueprint in peole with bipolar disorder. How does a decentralized MD see this disease that centralized psychiatrist have no answer for?

2. Bipolar disorder (BD) is a chronic and common psychiatric pathology, which can be particularly disabling. The disease has a global prevalence rate of 1–4%, begins at an early age, i.e. predominantly between 15 and 25 years old, and persists throughout the life of patients. BD is characterized by a recurrence of mood depressive episodes (pathological decrease in mood and energy), hypomanic or manic episodes (pathological increase in mood and energy), or even mixed episodes (simultaneous presence of depressive and manic symptoms).

These thymic episodes are interspersed with phases of clinical remission, known as “euthymic” episodes. The disease is associated with a high morbidity and mortality rate and due to the significant functional impact it induces, including during euthymic periods, BD is the cause of poor quality of life and is one of the ten most disabling diseases according to the World Health Organization.

The diagnosis of BD is mainly clinical and can be supported using scales or questionnaires. The diagnostic delay is estimated at around 10 years. This delay is clearly related to the heterogeneity of the clinical expression of the disease. The study of the literature shows that this delay in treatment seriously affects the prognosis, particularly on the functional level, and constitutes a major public health problem. In addition, there are no biomarkers, easily usable in current practice, to help the clinical decision for the diagnosis or for predicting the course or prognosis of the disease.

3. Sleep disturbances and sleep/wake rhythms are major in BD. These disturbances are observed during the different phases of the disease and are major symptoms of mood episodes and belong to the diagnostic criteria for depression, hypomania, and mania. In addition, these anomalies are also found during the euthymic phases of this disease. Indeed, patients suffering from BD would be more likely to present a more evening chronotype and a more languid and rigid circadian type than healthy subjects as well as a decrease in the efficiency of their sleep, an increase in sleep duration, an increased sleep latency and a prolongation of the duration of awakenings after the onset of sleep. These disturbances in sleep and wake/sleep rhythms are associated, among other things, with more frequent relapses, an alteration in the quality of life, and cognitive disorders.

Additionally, neurocognitive deficits are frequently associated with BD. Most typical deteriorations found are impairment of episodic verbal memory, executive functions, processing speed, and sustained attention. These troubles can be present during mood episodes but also in around 30% of patients during euthymic phases. Cognitive deficits of patients with BD have a direct impact on their psychosocial functioning, on the risk of relapse, on treatment adherence, or even on their ability to insight. Their early detection associated with the identification of prognostic and predictive biomarkers of the response to cognitive and functional remediation tools is essential in order to be able to offer early and appropriate treatment.

Now listen to what I said about consciousness here before going further. It occurs very early in the podcast:
youtube.com/watch?v=zCGnMY…

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☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆

@DrJackKruse

Mar 7

1. Martin is getting very close to understanding Uncle Jack. It seems I may have underestimated Levin, too.

ERP and Post-K-T Survival
The K-T extinction, triggered by the asteroid impact 66 million years ago, created a high-stress environment with reduced sunlight, disrupted photosynthesis, and scarce food—conditions that would elevate éR across ecosystems.
Eutherian mammals and theropod dinosaurs (evolving into birds) survived by modulating éR through specific adaptations: Mitochondrial capacity and Melanin are ERP measures.

Mitochondrial Amplification:
Birds: Birds have amplified mitochondria in flight muscles and appetite centers to manage the high éR of sustained flight and foraging. This optimization minimized dissipative losses, allowing them to exploit distant, viable habitats.

Mammals: Enhanced mitochondrial activity around the hypothalamus (potentially for glucose synthesis from altered light) to regulate energy under low-resource conditions. This reduced éR spikes from starvation or cold, stabilizing their bioenergetic circuit.

Melanocyte Shift: The rising éR of the KT asteroid caused life forms who made it through the event to reject reptile and amphibian adaptation of chromatophores for the amplification of melanocytes. This was then tied to leptin-melanocortin pathways to make survival in a food-poor world possible for the early therapod dinosaurs and small mammals. This amplification and reliance of melanin due to altered light lowered éR by streamlining pigmentation energy costs. This shift supported UV protection and thermoregulation, key for endothermic stability, while avoiding the oxidative stress of older pigment systems.

Endothermy: As the most unappreciated metric, quantum-tuned endothermy allowed both clades to maintain a controlled éR baseline. By optimizing mitochondrial proton gradients and electron tunneling, they sustained metabolic work despite external chaos, counteracting entropy more effectively than ectotherms. Well done @MitoPsychoBio & @drmichaellevin

2. My discussion on the Tetragrammaton podcast with Andrew Huberman doves deep into the role of melanin in quantum processing, and my breakdown aligns with many of the concepts they explore while adding a quantum biological spin. Let me unpack how melanin amplifies quantum processing in mammals, mainly through electron surge, spin coherence, and energy bandwidth, and why this was a game-changer for Eutherian mammals and birds post-K-T event.

I’ll also tie this back to the Energy Resistance Principle (ERP) of Picard and Levin and then link it to the very unappreciated metric of quantum-tuned endothermy, while addressing the cellular impacts and evolutionary implications I’ve raised for 20 years

3. Melanin’s Role in Quantum Processing
As discussed in the podcast, melanin is a wide-bandgap semiconductor that absorbs light across a broad spectrum (all 73 octaves) far beyond chlorophyll’s narrow 400-700 nm range. This property allows melanin to harness light energy in ways that plants can’t, fundamentally altering how animals process energy and information at a quantum level. This would have been highly adaptive when the sun was blocked because of how chlorophyll operates with sunlight to create all the food webs. In evolution, chlorophyll came first, then hemoglobin, and then the KT event amplified melanin biology when the sun was dimmed.

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☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆

@DrJackKruse

Mar 7

Sunlight, Staying Indoors, Nicotine, and Vasopressin

Remember, the military has a long history of understanding how nicotine and the stress response operate in soldiers. They gave soldiers Lucky Strikes in their K ratios to lower stress responses and provide an anxiolytic effect. Right after the war, the military studied these effects.

Military research showed that nicotine acutely stimulates vasopressin release by activating nicotinic acetylcholine receptors, particularly in the brainstem (e.g., nucleus tractus solitarius), which signals the hypothalamus to secrete vasopressin. Studies like Burn et al. (1945) noted nicotine’s antidiuretic effect (via vasopressin).

Studies on nicotine self-administration in rats show that it initially boosts vasopressin in the hypothalamic paraventricular nucleus (PVN).

DARPA, FAUCI, and the DoD, through Biden mandates, tried to force humans to stay indoors and encouraged this during COVID-19 lockdowns. This put them in front of more tech gear and screens, which led to chronic and intense vasopressin release. This would have stimulated the light stress injury cascade and blocked the regeneration pathways. Smokers avoided what many non-smokers could not. Now you know why. It had nothing to do with snake venom.

DARPA LEARNED THE LESSON FROM WW2

Nicotine’s anxiolytic effect is well-documented in smokers, especially when they are put under ANY stress. This includes light stress, viral stress, or jab stress. It acutely activates the hypothalamic-pituitary-adrenal (HPA) axis (raising cortisol and vasopressin). This fits with the military history in WWII. They passed out Lucky Strikes like today's pediatricians pass out adderall. DARPA studied why soldiers smoked to cope, and they found that nicotine tempered their stress response. The military later studied this in heavy trauma patients with significant blood loss from injuries. They confirmed these findings during DARPA's time at SRI.

Dehydration exacerbates stress and PTSD risk by amplifying HPA axis activity and causes vasopressin release. Studies on soldiers show dehydration also increases cortisol from POMC translation, leading to cognitive strain due to high blood glucose & insulin signaling.

DARPA’s Role: DARPA has explored hydration and stress since the 2000s, including projects on brain resilience and PTSD prevention. A 2010s DARPA program, “Targeted Neuroplasticity Training,” investigated physiological stressors. When I was treating Camp Shelby soldiers, they all told me that the DoD was highly interested in water purity when deployed in Iraq. Why? RO water minimizes osmotic stress, stabilizing vasopressin levels compared to mineral-heavy or impure water. A 2007 study on hydration and cognitive performance in soldiers shows that purified water reduces stress markers.

PTSD Link: PTSD involves HPA dysregulation, with altered vasopressin and cortisol responses. Nicotine’s use in Iraq (via smoking or patches) interacted with RO water’s effects, with pure water keeping baseline vasopressin lower, while nicotine provides acute stress relief. No declassified DARPA documents confirm this exact strategy. Still, my work with these soldiers told me they were studying these effects because, in the desert, they were very focused on soldier performance under stress.

2. When you go outside and get hit with UVA light, Nitric oxide is manufactured in your skin and their arterioles to bring those vessels closer to the surface. This raises the amount of NO. What does it do?
NO Binding to Hemoglobin: Effects on Oxygen and CO2 Exchange
Nitric oxide’s interaction with hemoglobin is a well-studied but often underappreciated aspect of its physiology, and NO biology highlights its relevance to the light-driven processes I’ve explored.

3. Here’s how it fits:
NO Binding Mechanisms: S-Nitrosylation: NO can bind to the cysteine residue (Cysβ93) in hemoglobin’s β-globin chain, forming S-nitrosohemoglobin (SNO-Hb). This reversible binding modulates hemoglobin’s function beyond oxygen transport. Nitrosylhemoglobin: NO can also bind directly to the heme iron (Fe²⁺) in the porphyrin ring, forming nitrosylhemoglobin, particularly under deoxygenated conditions. This competes with oxygen binding and influences oxygen affinity.

This means going in the sun makes you need less O2 on the arteriole side because the sun is giving your system a hypoxia exercise treatment. On the venous side it increases venous O2.

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☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆

@DrJackKruse

Mar 4

1. Benefits of Sun Exposure beyond Vitamin D:
'There is growing observational and experimental evidence that regular exposure to sunlight contributes to the prevention of colon-, breast-, prostate cancer, non-Hodgkin lymphoma, multiple sclerosis, hypertension and diabetes.'

'Initially, these beneficial effects were ascribed to vitamin D. Recently it became evident that immunomodulation, the formation of nitric oxide, melatonin, serotonin, and the effect of (sun)light on circadian clocks, are involved as well.'

'In Europe (above 50 degrees north latitude), the risk of skin cancer (particularly melanoma) is mainly caused by an intermittent pattern of exposure, while regular exposure confers a relatively low risk.' People spend more time inside under artificial light that links to skin cancers.
pubmed.ncbi.nlm.nih.gov/27876126/

2. What does the operating room for skin cancers look like in my clinic?

3. Modern humans have lost darkness while making their lives in alien suns. Artificial light at night is significantly correlated for all forms of cancer as well as lung, breast, colorectal, and prostate cancers individually. Immediate measures should be taken to limit artificial light at night in the main cities around the world and also inside houses."
Artificial light at night is unnatural. It changes the natural rhythm of every clock in the body.
Bright sunny days and dark nights are natural. Humans are designed to be in sync with nature.
While I don’t expect people to sit at home in the dark, there are ways to mitigate the negative effects of light at night.
Wear 100% blue light blocking glasses after the sun goes down.
Wear a sleep mask to bed.
Expose your naked eyes to morning sunshine to start the day.
Get night bulbs (that have zero blue light) and turn them on instead of bright daytime lights.
Try to stop looking at screens after the sun goes down.
Get consistent sleep every night.
You should naturally be tired by 10 and naturally wake up with the sun if your circadian rhythm is in tune with nature.

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More from @DrJackKruse

☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆

☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆

☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆

☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆

☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆

☣️ Pleb Kruse = BTC foundationalist in exile 🟩🔆

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