Dr.Sayajirao Gaikwad Profile picture
Jul 29, 2025 9 tweets 2 min read Read on X
🫀 Key Cardiac Risk Markers You Shouldn’t Ignore
Heart attacks in 20s & 30s are becoming frighteningly common.
Fit on the outside ≠ Healthy on the inside.
Here’s how to investigate early & prevent silent cardiac risk 🧵 👇
🔴 1. Lipid Profile is just the beginning
Check more than just total cholesterol.
✅ LDL (bad cholesterol)
✅ HDL (good cholesterol)
✅ Triglycerides (TG)
✅ VLDL

🔍 Ideal:
•TG < 100
•HDL > 50
•LDL < 100
•TG/HDL ratio < 2
🔴 2. ApoB & ApoA1 – Better than LDL
🔸ApoB = Number of artery-clogging particles
🔸ApoA1 = Protective particles

✅ Ideal ApoB < 90
✅ ApoB/ApoA1 Ratio < 0.6
This is a stronger predictor of heart disease than LDL alone.
🔴 3. Lp(a) – The silent genetic risk
🔸Not tested in basic reports
🔸Genetically inherited
🔸Can increase heart attack risk even if other markers are normal

✅ Ideal Lp(a) < 30 mg/dL
📌 Test it once in life—even if you’re young.
🔴 4. hsCRP – Inflammation matters
🔸High-sensitivity C-Reactive Protein
🔸Marker of chronic low-grade inflammation

✅ Ideal < 1.0 mg/L
🔥 Chronic inflammation silently damages arteries.
🔴 5. Homocysteine – B12 & Heart Link
🔸Elevated in B12/folate deficiency
🔸Promotes clotting & damages blood vessels

✅ Ideal < 10 µmol/L
📌 If high, correct B12, folate, B6 levels.
🔴 6. Fasting Insulin & HOMA-IR
🔸Most missed test. Insulin resistance often starts years before diabetes.

✅ Fasting insulin < 6
✅ HOMA-IR < 1.5

📌 Even with normal sugar, high insulin = silent metabolic risk.
🔴 7. CAC Score (Calcium Score CT)
🔸Non-invasive scan to detect early plaque in coronary arteries
🔸Score 0 = very low risk
🔸Higher scores = hidden artery blockage

📌 Highly recommended if you have family history or are >35 with risk markers.
🧠 Prevention is not just avoiding junk food.
It’s about testing early and tracking the real markers of silent cardiac risk.
✅ Don’t wait for chest pain.
✅ Don’t assume fitness = health.
✅ Investigate > Guess
✅ Act early = Live longer

#HeartHealth #PreventHeartAttack #MetabolicHealth

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More from @DietDrsayajirao

Dec 14, 2025
Eggs, Nitrofurans & Cancer : Let’s Debunk the Fear (With Science)
Recent viral claims say “eggs cause cancer” due to nitrofuran residues.
This is misleading. Here’s the fact-based breakdown 🧵 🧠⬇️
1️⃣ What’s the panic about?
A lab test detected trace AOZ (~0.73 µg/kg) in one egg batch.
AOZ is a marker of a banned antibiotic (furazolidone).
Headlines followed: “Eggs are carcinogenic.”

That leap is scientifically wrong.
2️⃣ What are nitrofurans?
Old antibiotics once used in poultry.
Banned globally as a precaution, not because food caused cancer in humans.

📌 Evidence of cancer =
➡️ High-dose rat/mice studies
➡️ NOT real-world human food exposure
Read 12 tweets
Nov 16, 2025
THE “LONGEVITY CHECKLIST”
✓ Low visceral fat
✓ Low fasting insulin
✓ Strong muscles
✓ High VO₂ max
✓ Good sleep
✓ Whole-food diet
✓ Fasting window 14–16 hours
✓ Stress in control
✓ No smoking, minimal alcohol
✓ Key nutrients optimized
✓ Social connection
✓ Purpose & lifelong learning
1) Cardiorespiratory fitness (VO₂max)
Higher VO₂max is one of the strongest independent predictors of lower all-cause and cardiovascular mortality. Even small improvements in aerobic capacity translate into measurable increases in life expectancy. Regular Zone-2 training with occasional intervals is consistently shown in cohort data to improve metabolic health, cardiac efficiency and overall survival.
2) Resistance training
Meta-analyses show strength training is linked to ~15–27% lower all-cause mortality when done 30–60 minutes per week. It preserves muscle mass, prevents sarcopenia, improves insulin sensitivity, strengthens bone and reduces cancer and cardiovascular mortality. Muscle is one of the most protective biometrics you can build after 40.
Read 7 tweets
Nov 2, 2025
Studies show :
• 2 nights of 5-hour sleep ↓ testosterone 10–15%
• ↑ insulin resistance 24%
• ↑ cortisol & hunger hormones

Yet most people spend ₹10,000/month on supplements not sleep.
What if your real deficiency is rest? 🧵
1️⃣ Sleep controls your hormones.
Cut your sleep short → cortisol spikes, leptin drops, ghrelin rises.
You crave sugar, overeat 300+ extra calories/day, and blame “low willpower.”
It’s not willpower. It’s biology.
2️⃣ Sleep builds your body.
Just one week of 5-hour nights ↓ testosterone 10–15% and ↓ growth hormone 20%.
Even with perfect diet and workouts, recovery tanks.
You can’t out-train or out-supplement poor sleep.
Read 11 tweets
Oct 30, 2025
Diet for Diabetes What Science Actually Says
Let’s start with a truth:
Diabetes isn’t just a blood sugar problem.
It’s a metabolic energy problem where your body becomes resistant to insulin, the key hormone that helps glucose enter your cells.
So, managing diabetes = improving insulin sensitivity.🧵
The goal of a diabetic diet isn’t “eat less sugar.”
It’s to lower insulin demand and glucose spikes throughout the day.
That means:
👉Control carbs (quality + quantity)
👉Prioritize protein
👉Add healthy fats
👉Support gut & liver health
Step 1: Control Carbohydrates (Smartly)
👉 Choose low-glycemic carbs they raise blood sugar slowly.
Examples:
👉Millets (foxtail, barnyard, little millet)
👉Quinoa
👉Rolled oats
👉Vegetables (especially green, fibrous ones)

🚫 Limit or avoid:
White rice, refined flour, sugary drinks, bread, breakfast cereals, fruit juices.
Read 14 tweets
Oct 29, 2025
PCOD vs PCOS : They’re NOT the Same Thing

Let’s clear one of the most misunderstood topics in women’s health.
Most people use PCOD and PCOS interchangeably but scientifically, they’re different.
#PCOS #HormoneHealth #WomensHealth
1️⃣ PCOD = Polycystic Ovarian Disease
PCOS = Polycystic Ovary Syndrome

PCOD is a functional disorder of the ovaries.
PCOS is a systemic endocrine-metabolic syndrome that affects multiple organs not just the ovaries.
2️⃣ The Core Difference:
PCOD is a temporary, often lifestyle-driven imbalance where ovaries release many immature eggs.
PCOS is a chronic hormonal disorder marked by insulin resistance, androgen excess, and ovulatory dysfunction.

PCOD = symptom
PCOS = syndrome
Read 14 tweets
Oct 25, 2025
The Most Important Muscle You’re Probably Ignoring and It Could Transform Your Metabolic Health

Let’s talk about the soleus a small muscle in your calf with a massive impact on glucose control, fat metabolism, and longevity.
A thread 🧵👇
1️⃣ The Soleus: The Unsung Metabolic Engine

It’s a deep calf muscle that works quietly every time you stand or walk.
~70–90% slow-twitch fibers.
Built for endurance, not explosiveness.

But here’s the shocker this tiny muscle can influence how your entire body processes sugar and fat.
2️⃣ Why the Soleus Is Special

Most muscles burn stored glycogen first.
The soleus? It burns blood glucose and fatty acids directly even at rest.

That means when it’s active, it keeps blood sugar and lipids under control without demanding much insulin.

This is why scientists call it a “metabolic powerhouse.”
Read 11 tweets

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