The CDC reports 29 states & DC are experiencing High or Very High transmission.
The heat map is a patchwork quilt with COVlD levels varying considerably state by state.
Transmission is shifting north + east.
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PMC COVlD Dashboard, Sep 22, 2025 (U.S.)
COVlD levels by state, AL to MS.
Note that even levels the CDC calls "Low" like Guam at 1.5% actively infectious are at the threshold where I would tell people who have lapsed that it's time to #MaskUp.
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PMC COVlD Dashboard, Sep 22, 2025 (U.S.)
COVlD levels by state, Missouri to Wyoming.
New York is a good example of where the CDC label of "Moderate" simply does not cut it. 1 in 49 is very high, and the data quality statewide has been poor.
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PMC COVlD Dashboard, Sep 22, 2025 (U.S.)
PMC presently estimates transmission peaked on Sep 6 at 1.24 million new daily infections.
Our forecasts were in the range of 1.0-1.3 mil with a peak timed to Sep 6-13, based on rocky & lagged real-time data. Hope it helped you.
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PMC COVlD Dashboard, Sep 22, 2025 (U.S.)
New weekly infections are estimated at 6.5 million nationwide, leading to thousands of new long-term sequelae, and an eventual ≈3,000 excess deaths.
Only about 1 in 44 infections are being reported.
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PMC COVlD Dashboard, Sep 22, 2025 (U.S.)
Current SARS-CoV-2 transmission (red line) is eerily tracking that of 2 years ago (yellow).
The good news is the sudden apparent decline from peak transmission. To see the bad news track the yellow line's autumn "lull."
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PMC COVlD Dashboard, Sep 22, 2025 (U.S.)
Our central forecast has national transmission declining steadily the next several weeks, but there is considerable statewide variation.
Historically, 60% of SARS-CoV-2 transmission occurs on the back end of waves.
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PMC COVlD Dashboard, Sep 22, 2025 (U.S.)
Protect yourself. You have value. The long-term benefits of reducing cumulative reinfections are tremendous.
The vast majority of PMC dashboard users protect themselves with multilayered mitigation.
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Levels are flat during a relative "lull" in transmission.
▪️1 in 187 estimated actively infectious
▪️260,000 estimated new daily infections
▪️High: OK, MS, WV
▪️Moderate: VT
▪️All other states low/very low in relative transmission
🧵THREAD 1/6
COVID-19 persists in 2026.
We are in a relative "lull" following a 12th wave, but at a baseline of 200-300K estimated new daily infections.
Transmission was lower in the era many refer to as #DuringCOVID, when multi-layered mitigation was used instead of denial.
🧵THREAD 2/6
Transmission during a "lull" is high in an absolute sense. Many people are getting infected.
Simultaneously, its low in a relative sense, or compared to so-called "typical" transmission. In most places, it's a safer time for medical/dental care.
Transmission is stable in a relative "lull" nationally between waves.
We estimate that approximately 313,000 people are still getting infected per day, with outbreaks radiating from TN and MS.
🧵1 of 10 (don't miss #10)!
With limited data reported, Mississippi has an estimated 1 in 27 residents actively infectious.
In a room of 25 people, that's a 61% chance of exposure, if no testing/isolation protocols.
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1 in 24 people in Tennessee are estimated to be actively infectious with SARS-CoV-2. That's a 65% chance of exposure in a room of 25 people where nobody is testing/isolating.
This is an unethically misleading study with findings easily explained by residual confounding. Some health systems and patients have thorough record keeping. Others don't. All sorts of variables will correlate (infections, cancers, anything else tracked in medical records).
This is a really obvious issue for an international epi study. It should not have been published.
The above study is using the same processes the anti-vaxxers use -- junk epi that does not account for confounding -- to support whatever pre-conceived notions the authors have, with absurdly large effects.
Denial is but one of several obvious defense mechanisms people use to try to block their awareness of the ongoing toll of COVID-19. There are many others.
Short-term capital also plays a role, but even that requires a large dose of defense mechanisms.
During this 12th COVlD wave, the CDC reports 1-in-3 states have "High" or "Very High" levels.
PMC estimates the proportion of residents actively infectious (prevalence):
◾️USA: 1 in 67
◾️IA: 1 in 27
◾️MI: 1 in 25
◾️IN & CT: 1 in 23
◾️ME: 1 in 21
◾️OK & SD: 1 in 17
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On average, Americans have have 5.0 cumulative SARS-CoV-2 infections.
This week's infections are expected to result in 1/4 to 1 million new #LongCOVID conditions and ≈2,000 excess deaths.
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The wave peak is now estimated >10% higher than last week at 1.2 million new daily infections, nearly double the Delta wave.
We expect sustained high transmission (≈600,000 to 750,000 new daily infections) the next few weeks as COVlD circulates through schools/families.
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