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Aaron Newman Lab
@AaronNewmanLab
Computational biology, cancer genomics, & stem cell bioinformatics lab @Stanford @czbiohub
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Mar 6, 2023
•
10 tweets
•
7 min read
Excited to announce our new method
#CytoSPACE
for mapping single cells from a reference atlas to
#SpatialTranscriptomics
(ST) data at high resolution, out now in
@NatureBiotech
! 1/10
nature.com/articles/s4158…
Available assays for ST lack single-cell resolution (e.g.
#Visium
) or have limited gene recovery (e.g.
#MERSCOPE
).
CytoSPACE computationally reconstructs tissue specimens to obtain high gene coverage and spatially-resolved scRNA-seq data suitable for downstream analysis. 2/10