Aaron Newman Lab Profile picture
Computational biology, cancer genomics, & stem cell bioinformatics lab @Stanford @czbiohub
Mar 6, 2023 10 tweets 7 min read
Excited to announce our new method #CytoSPACE for mapping single cells from a reference atlas to #SpatialTranscriptomics (ST) data at high resolution, out now in @NatureBiotech! 1/10

nature.com/articles/s4158… Available assays for ST lack single-cell resolution (e.g. #Visium) or have limited gene recovery (e.g. #MERSCOPE).

CytoSPACE computationally reconstructs tissue specimens to obtain high gene coverage and spatially-resolved scRNA-seq data suitable for downstream analysis. 2/10