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Arnav Agarwal Profile picture
Arnav Agarwal
@ArnavAgarwalMD
Internal Medicine physician. @UofTMedicine 》@McMasterGIM @MacDeptMed. ★ Evidence synthesis • guideline development • advocacy • editor @HealthyDebate.
Mar 3, 2022 • 13 tweets • 15 min read
🔥 Our latest @WHO living guidance on drugs for #COVID19:

Severe/critical:
✅steroids, IL-6RB, baricitinib
🔷REGN-COV
🔶other JAK2i, plasma

Non-severe:
🔷molnupiravir, REGN-COV, sotrovimab
🔶steroids
🚫plasma

All:
🔶remdesivir, ivermectin
🚫HCQ, LPV/r

bit.ly/3pAK6Oe Important considerations/caveats:
✨Choice between baricitinib & IL-6RB for severe/critical COVID-19 depends on availability & clinical/contextual factors.
✨In non-severe illness, molnupiravir, sotrivimab & casirivimab-imdevimab are weakly recommended for those at highest risk.
Dec 7, 2021 • 9 tweets • 13 min read
🔊Our latest @WHO living guidance on treatments for #COVID19, out today:

For severe/critical:
✅steroids
✅IL-6 RB
🟨mAb
🟧convalescent plasma🔥

For non-severe:
🟨mAb
🟧steroids
🚫convalescent plasma🔥

For both:
🟧remdesivir
🟧ivermectin
🚫HCQ
🚫LPV/r

bit.ly/3pAK6Oe ImageImage Two recommendations:
🌟against administering convalescent plasma for non-severe covid-19.
🌟against administering convalescent plasma for severe or critical covid-19, except in the context of a clinical trial. Image