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Bill Lagakos Profile picture
Bill Lagakos
@CaloriesProper
PhD Nutritional Biochemistry & Circadian Biology. Allergic to green kryptonite. For personalized health consulting services: drlagakos@gmail.com
Feb 17, 2024 • 17 tweets • 4 min read
As more rodent keto studies are emerging, please read this first:

*strain? FA composition? duration? et ceteracaloriesproper.com/rodent-keto-st… Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice sciencedirect.com/science/articl…
Jun 25, 2023 • 5 tweets • 2 min read
A ketogenic diet substantially reshapes the human metabolome

Confounded by weight loss. Again 🙄
@agingdoc1 @HealthyFellowclinicalnutritionjournal.com/article/S0261-… Mitochondrial DNA and mental wellness (anxiety & depression) nature.com/articles/s4139…
Jan 5, 2023 • 8 tweets • 5 min read
Update: I tried a 30-rep set of squats with my regular warm-up weight (135 lbs) the other day as per @AJA_Cortes' recommendation

1) was super-winded after
2) kinda felt a little pukey
3) omg leg/quad pump
4) now: legs sore af

@AJA_Cortes In reflection, I should've worked up to that from my usual 10-rep sets (working up to doubles/triples)
Jan 4, 2023 • 4 tweets • 2 min read
en.wikipedia.org/wiki/XY_sex-de… en.wikipedia.org/wiki/Klinefelt…
Jan 4, 2023 • 5 tweets • 1 min read
Piano Concerto No. 2 in C Minor, Op. 18: I. Moderato

Arthur Rubinstein

Vladimir Ashkenazy
Nov 27, 2022 • 9 tweets • 3 min read
🤡 Practically every single cell in your body synthesizes cholesterol yet carnivores are telling you to get more dietary cholesterol from steak and eggs so you can make testosterone and vitamin D.
Nov 27, 2022 • 11 tweets • 4 min read
Just overheard: "the intermittent fasting people on Twitter are the only ones who think skipping breakfast in the morning is better. The research shows tapering off food intake as the day progresses is healthier." No one is hungry in the morning, but gotta get that protein for the MPS & entraining circadian rhythms.

Family time at dinner is great but it doesn't have to be a feast or the biggest meal of the day, every day.
Nov 26, 2022 • 4 tweets • 1 min read
American Psycho (2000, amzn.to/3U7pwm3) is a pretty good book -> movie crossover. Most book -> movie crossovers don't go over well with original book readers. In the book (amzn.to/3VvHvDY) and film, Bateman is clearly insane and delusional. One of the final movie scenes where he frantically confesses to his lawyer he's killed 100s of people; in the book it's 1000's cuz a book isn't limited to 2 hours.
Nov 26, 2022 • 4 tweets • 2 min read
Make sure you know the context, what foods or diets are being compared.

Carnivore or vegan vs. healthy omnivore?

Big difference between that comparison and comparing any of them with UPF-rich SAD. ImageImage Also, some people heal and do great on higher carb diets by ditching UPFs and alcohol.

So is this really a comparison of low carb vs. high carb foods?

LC/carnivores always compare animal foods to ultra-processed junk foods.
Nov 25, 2022 • 5 tweets • 2 min read
List of countries by food energy intake
en.m.wikipedia.org/wiki/List_of_c… ImageImage en.wikipedia.org/wiki/List_of_c…

someone please make a simple Excel graph 🙏🙏🙏 Image
May 15, 2022 • 4 tweets • 1 min read
Judas Priest

Breaking The Law (1980)
archive.org/details/Judas_…

probably the best thing that ever came from England 🤟 *their Birmingham, not my former stomping grounds in the real Birmingham, Alabama en.wikipedia.org/wiki/Judas_Pri…
May 15, 2022 • 18 tweets • 13 min read
Testosterone Administration Induces A Red Shift in Democrats openicpsr.org/openicpsr/proj… holy shit @AJA_Cortes @Cernovich @AJA_Cortes @Cernovich Testosterone release and social context: When it occurs and why sciencedirect.com/science/articl…
May 14, 2022 • 7 tweets • 2 min read
Took Luna out for a nightly walk outside, with only one visible anomaly and no chem trails 😂

*note the baby-kitten-sized loose fitting harness ImageImage Loud motorcycle drove by in one direction, she slipped out of the harness and sprinted in the other direction, into oncoming traffic. I dove to grab her and roll out of the oncoming traffic. Knees look pretty bad, too. Image
Apr 29, 2022 • 6 tweets • 3 min read
Yo soo many n=1 potato dieters losing weight slimemoldtimemold.com/2022/04/29/pot… The global obesity pandemic: shaped by global drivers and local environments
thelancet.com/journals/lance… (not 🥔)
Apr 29, 2022 • 5 tweets • 6 min read
"Approximately 1 kg of silver in every Tesla on average" reddit.com/r/Silverbugs/c… @PeterSchiff @APompliano @PeterMcCormack 🤔 @PeterSchiff @APompliano @PeterMcCormack goldsilver.com/blog/why-elon-… @GoldTelegraph_ @MilesFranklinCo
Apr 27, 2022 • 6 tweets • 2 min read
#eTRF 2022
caloriesproper.com/etrf-2022/ gettr.com/post/p17delu81…
Apr 27, 2022 • 5 tweets • 1 min read
Ruh-roh... Caloric restriction does not enhance longevity in all species and is unlikely to do so in humans pubmed.ncbi.nlm.nih.gov/16858629/ Importance of circadian timing for aging and longevity pubmed.ncbi.nlm.nih.gov/34001884/
Jan 3, 2022 • 4 tweets • 2 min read
The French Dispatch (2021, amzn.to/3sRR8RZ). If you like Wes Anderson films... 👏 💎 👏 highly recommended disclaimer: I like many if not all Wes Anderson's films

The Royal Tenenbaums amzn.to/32B65NW

Moonrise Kingdom amzn.to/3EPosf0

The Grand Budapest Hotel amzn.to/32B67p2

Isle of Dogs amzn.to/3EPZjRj

(some are free to watch online)
Dec 10, 2021 • 4 tweets • 1 min read
haha true my experience 100%

old hand-me-downs >>>
Dec 9, 2021 • 4 tweets • 1 min read
Have any famous politicians started a gofundme to support the rioters who burned the Fox Christmas Tree? washingtonpost.com/politics/2020/…
Apr 1, 2021 • 5 tweets • 1 min read
Eight days of water-only fasting induces super high ketones! but massive muscle wasting and testosterone plummets ncbi.nlm.nih.gov/pmc/articles/P… so why would you do this people can do some pretty impressive mental gymnastics while trying to rationalize some behaviors... 😬