Bioengineer, computational immunologist, futurist, husband, father, entrepreneur. Founder, CEO & President of Centivax
Dec 1, 2020 • 5 tweets • 2 min read
1. RNA vaccine ingredients. These vaccines have RNA wrapped up inside tiny droplets of oil and cholesterol. The lipids are similar to your cells - they have mild chemical charge on one side that orients the RNA (short-lived genetic message encoding the coronavirus spike protein) 2. ... inside them (biological systems do this all the time). There is also polyethalene glycol - this is a common compounds used in medicines to make them more water soluble, it’s also used as a constipation medicine when given at high doses and in a bunch of other applications.
Mar 23, 2020 • 4 tweets • 2 min read
Interviewed on CNBC this morning regarding our #COVID19 antibody cure. We discuss why a vaccine will take too long to avert the medical and economic crisis in 2020. Vaccines don’t work well in the elderly and immunocompromised. Thus we need an antibody. cnbc.com/video/2020/03/…
We discuss our plan for rapid GMP partnerships, to run a Phase I/II study in the summer followed by compassionate use release in the fall. This is the fastest way to avert the humanitarian and financial crisis
Mar 8, 2020 • 4 tweets • 2 min read
Comparing two estimates: #California 03/07/20: about 100 #COVID19 cases confirmed. Estimate #1: Assuming 20% of cases are severe enough to seek treatment, and 25% of such cases were actually tested at hospitals, I estimate 2000 infected people in the state.
Estimate #2: given #COVID19 R0=2.5, a 6 day infection cycle, spreading beginning around same time as DNA estimated Seattle cases of 7-weeks ago, we would have 669 cases from a single individual, and 1043 if we had one new spreader arrive per week until Chinese air travel ceased.