Derm @bwhdermatology (acne, epi, patient-reported outcomes, antibiotic stewardship, high-value care). Assoc Ed @JAMADerm. Views are mine, not medical advice.
Mar 6 • 8 tweets • 2 min read
This is an important report/FDA petition, but I think it requires some additional context to avoid making the wrong conclusions. Before we consider banning the sale of one of the most beneficial acne treatments, let's review what is actually presented in the report. A thread: 1/8
The premise of this report is that benzoyl peroxide has the potential to thermally decompose into benzene, which has carcinogenic potential (i.e. we don't want it in our skin care products).
2/8
Nov 30, 2022 • 9 tweets • 4 min read
While pregnancy can be associated with worsening of acne, it can be challenging to treat given more limited available options. In this Tweetorial, we'll explore how to approach acne during pregnancy. #MedEd#dermtwitterlink.springer.com/article/10.100…
1/8
First, it is important to acknowledge that we have limited data on the safety of many treatments in pregnancy. Therefore, it is critical to engage in shared decision making depending on individual willingness to accept risk/uncertainty and to with our obstetrics colleagues.
2/8
Aug 26, 2022 • 19 tweets • 6 min read
Isotretinoin is a highly effective treatment for acne and the only acne treatment that can provide a lasting remission. However, there are many misconceptions about isotretinoin. In this updated Tweetorial, let's bust some common isotretinoin myths! #dermtwitter#JBAcneTips 1/19
Myth #1 - Isotretinoin and depression: Multiple meta-analyses have found that there is no population level association between isotretinoin use and depression. In fact, isotretinoin may be associated with decreased depressive symptoms. 2/19 jaad.org/article/S0190-…
Jul 27, 2021 • 17 tweets • 7 min read
We’ve busted some common #isotretinoin myths, but what about actual side effects of isotretinoin in the treatment of #acne. In this Tweetorial, we’ll review the most common side effects and how they can be managed. #dermtwitter#MedEd 1/16
The most commonly reported side-effect is mucocutaneous dryness. It is dose dependent, occurring in 75% of those treated with 0.25-0.5mg/kg/day and in nearly 100% treated with 1mg/kg/day. 2/16 europepmc.org/article/med/21…
Jul 13, 2021 • 14 tweets • 5 min read
What is the optimal approach to monitoring patients being treated with #isotretinoin for #acne? In this Tweetorial, let’s review the evidence for best practices! #dermtwitter#MedEd 1/13
First, why do we monitor labs?
Benefits:
-Prevent severe adverse effects
-Guide dosing
Downsides:
-Pain
-Fear
-Cost
2/13
May 26, 2021 • 15 tweets • 5 min read
Isotretinoin can be a highly effective treatment for #acne and is the only acne treatment that can provide a lasting remission. However, there are many misconceptions about #isotretinoin. In this Tweetorial, let's bust some common isotretinoin myths! #dermtwitter 1/13
Myth #1 - Isotretinoin and depression: Multiple meta-analyses have found that there is no population level association between isotretinoin use and depression. In fact, isotretinoin may be associated with decreased depressive symptoms. 2/13 jaad.org/article/S0190-…
Mar 19, 2021 • 7 tweets • 3 min read
Just out in @JAADjournals, interesting cohort study led by @ArielleNaglerMD evaluating whether there is an increased risk of suicidality among #acne patients treated with #isotretinoin. A quick thread 1/7 #dermtwitter#dermatology pubmed.ncbi.nlm.nih.gov/33727021/
The authors conducted a cohort study evaluating the rate of psychiatric disorders and suicidality among 3 cohorts: those with acne treated with isotretinoin, those treated with antibiotics only, and those in the general population. 2/7
