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Fred Wu, MD 🫀 吳明杰 Profile picture
Fred Wu, MD 🫀 吳明杰
@FredWuMD
I take care of adolescents & adults with congenital heart disease. #MedPeds #ACHD @BostonChildrens @BrighamWomens. Clinics in Boston, Providence, & Lebanon, NH.
May 17, 2021 • 22 tweets • 18 min read
Dr. Lantin giving a Top 10 review of #ACCACPC research in 2020, a truly crazy year! #ACC21 🔟 No mention of 2020 could possibly ignore the effects of the global pandemic on research, patient care, and the way we share knowledge. #COVID19 #ACC21
May 16, 2021 • 9 tweets • 7 min read
Of interest to the #CHD and #ACHD community, Matthew Gillespie of @HeartCare4Kids, a leader in transcatheter pulmonary valves, gave an update on the state of the art over in the Right Sided Valve Interventions session, and as he rightly points out, it all started with CHD! #ACC21 Who needs pulmonary valve replacement?
👉~40K babies born w/ #CHD each yr
👉~22% have RVOT abnormalities
👉For those w/ RV-PA conduits we've had Melody/Sapien valves
👉For the 85% of RVOT pts w/o conduits with PR, these usu won't work due to dilated/distorted/dynamic RVOTs
#ACC21
May 16, 2021 • 6 tweets • 6 min read
Here are a couple of #ACC21 posters on pregnancy outcomes for women with heart disease, one from @LLUHealth on #CHD with RVOT dysfunction and one from @HopkinsMedicine on valvular heart disease, worth checking out. @doctorpianist @AllisonGHaysMD @kalamityjack #CardioObstetrics In @abbykhanmd's talk Saturday, she highlighted three commonly used risk models for predicting adverse outcomes in pregnant women with heart disease: the modified WHO criteria, CARPREG II, and ZAHARA. #ACC21
May 15, 2021 • 15 tweets • 8 min read
Starting off the Nuts & Bolts of Pregnancy and Congenital Heart Disease session with a pre-test question... #CardioObstetrics #ACC21 #ACHD Keep this chart in mind. Pregnancy is a prolonged period of cardiovascular stress with increased cardiac output, plasma volume, and heart rate. Things get really interesting during labor/delivery with acute increases in BP and CO. Image
Aug 29, 2020 • 10 tweets • 6 min read
Happy #VivienThomasDay! Today marks 110 years since the birth of Dr. Vivien Thomas. Although he never went to medical school, the surgical techniques he developed, such as the BTT shunt, are the foundation on which congenital heart surgery today was built. #CHD #ESCCongress2020 After graduating from high school, Thomas enrolled at Tennessee Agricultural & Industrial State College (now @TSUedu) as a pre-med. Unfortunately, the Great Depression depleted his savings, so he left college and found work as an assistant in Alfred Blalock's lab at @VUmedicine.
Jul 20, 2020 • 11 tweets • 4 min read
July 19, 1955, marked the last time that Dr. C. Walton Lillehei carried out a heart operation using the controlled cross-circulation technique. The patient was 5-year-old Paul Mathieu who was born with a ventricular septal defect. Here's a bedtime story for you history buffs... In the early 1950s, few cardiac anomalies could be corrected or palliated. Valve stenosis had been treated with valvotomy. PDA and CoA had been repaired in 1938 and 1944. And kids with tetralogy of Fallot were being palliated with Blalock-Taussig shunts.
Jan 7, 2019 • 11 tweets • 6 min read
On the night of January 6, 1968, @StanfordMed surgeon Norman Shumway transplanted the heart of 43-year-old Virginia White into the chest of 54-year-old Mike Kasperak. It was the first adult heart transplant to be performed in the United States. #medhistory #DonateLife Dr. Norman ShumwayMike Kasperak and wifeVirginia White By 1967, Shumway had already spent over a decade researching heart transplantation. In 1959, he and Richard Lower had performed the world's first successful heart transplant in a dog. Thus it was widely expected that he would be the first to perform a human heart transplant.
Dec 5, 2018 • 22 tweets • 6 min read
It's remarkable how quickly heart transplantation took off after Barnard reported his first on December 3, 1967. By August 15, 1969, over a period of less than 2 years, there had been 144 heart transplants performed worldwide (excluding xenotransplants) in 20 countries! Just for fun, let's see if you guys can guess the order in which countries performed their first respective heart transplants... I'll start with Christiaan Barnard's first transplant in South Africa and go through them in chronological order. I think you might be surprised!
Sep 12, 2018 • 16 tweets • 5 min read
To date, smallpox is the only major human disease that has been eradicated. September 11 happens to mark 40 years since Janet Parker became the last person ever to die from smallpox, and if you're interested, I thought I'd briefly share the story of this tragic milestone. Smallpox is a viral infection that has been around for millennia. It was characterized by a fever followed by an eruption of skin lesions that ranged from very mild to overwhelming and lethal. Ramses V, who died in 1156 BCE, is believed to be one of the earliest known cases.
Sep 3, 2018 • 8 tweets • 4 min read
It's open heart surgery's 66th birthday! On September 2, 1952, Dr. F. John Lewis at @UMNChildrens closed an atrial septal defect in 5yo Jacqueline Johnson using only total-body hypothermia, allowing him to halt her circulation for 5-1/2 minutes as he performed the operation. #CHD Using cooling blankets, Jacqueline was cooled to 28°C before her chest was opened, her systemic veins and pulmonary artery were clamped, and her right atrium opened. In the photo Lewis appears at the near side of the table. Standing on a stool behind him is Dr. Walt Lillehei.
Aug 14, 2018 • 5 tweets • 3 min read
Anyone remember the young man pictured here with Princess Di? On Aug 13, 1985, at 3 years old, Jamie Gavin of Dublin made headlines internationally as the youngest person at the time to undergo heart-lung transplant. The surgery was performed by Sir Magdi Yacoub. #CHD #DonateLife Jamie was born with hypoplastic left heart syndrome (#HLHS). Surgical options then were few. Bill Norwood had only just published his initial series on HLHS palliation; most centers remained wary. In 1984, another baby with HLHS, Baby Fae, received a baboon heart transplant.
May 24, 2018 • 18 tweets • 6 min read
Dr. Helen Taussig, considered to be the founder of pediatric cardiology and best known for her role in developing the Blalock-Taussig shunt operation for "blue babies," was born 120 years ago today. Happy birthday, Dr. Taussig! #CHD As several others have pointed out, Dr. Taussig persisted in the face of great adversity—no small part of which was due to her gender at a time when medicine was dominated by men—to become one of the most influential physicians of our time. A few highlights...