Professor @DSMOtago, Director @CMOR_Otago Centre for Musculoskeletal Outcomes Research @otago university; PhD, DPT, #MSkD clinical epidemiology, #osteoarthritis
Feb 13, 2023 • 8 tweets • 3 min read
OK: 1. Research on treatments should follow a pathway. It’s meant to begin with efficacy “can it work?” along with mechanistic studies on “how does it work?”. Once efficacy has been established, it’s time to move on to effectiveness “does it work for in the intended population”?
2. Efficacy studies are your classic placebo-controlled trial: ideal conditions, high internal validity. I think people misunderstand the role of efficacy studies. We don’t need many of these to answer “can it work?”.
Aug 8, 2021 • 8 tweets • 2 min read
Are Manual Therapy or Booster Sessions Worthwhile in Addition to Exercise Therapy for Knee Osteoarthritis? Economic Evaluation and 2-Year Follow-up of a RCT.
**50 days' free access** authors.elsevier.com/c/1dXi48nLVhjB…2/7 Compared with conventional delivery of Ex Ther (12 consecutive sessions), either distributing the sessions over a year using 8 consecutive sessions then 4 later "booster" sessions, OR adding Manual Therapy, improved outcomes and were cost-effective at 2yrs (& 5yrs projected)