5 years ago, I proposed using #DeepLearning to predict response to immunotherapy in TCR-Seq.
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Last year, we published #DeepTCR. Today, I am proud to share its application in cancer immunology, now out in @ScienceAdvances #ScienceResearch
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science.org/doi/10.1126/sc… This project started with a hypothesis that if a specific antigen-specific response was characteristic of responses to immunotherapy, then this should be reflected in the TCR repertoire/sequences.

After all, the TCR repertoire is ground truth for the antigen-specific response.