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Manuel Leonetti Profile picture
Manuel Leonetti
@LeonettiManuel
Quantitative Cell Science group leader @czbiohub, genome engineer, systems biologist.
Mar 30, 2021 • 8 tweets • 6 min read
Endogenous tagging + 3D live-cell imaging + mass-spec interactome = opencell.czbiohub.org, an open-source map of the human proteome. So excited for our first release, wonderful collaboration with @labs_mann @loicaroyer & many other colleagues. @OpenCellCZB (2/8) We used endogenous #CRISPR tagging with fluorescent probes to map both localization and interactions of proteins in their native cellular context.