(1/9) Interesting study recently published in @ehj_ed providing a comprehensive description of microvascular function in an animal model of 💔#takotsubo💔 - however, can we call it a microvascular disease? Some thoughts to challenge this view (thread 🧵)academic.oup.com/eurheartj/arti… (2/9) The authors used transaortic contriction to elicit #takotsubo in mice. They performed it on mice null for Kv1.5 channels and double transgenic mice with inducible Kv1.5 (plus controls): this elegantly reiterates the role of microvascular dysfunction (MD)...

Glad to share our latest publication on #WhyCMR with T1 and T2 mapping in #takotsubo syndrome 😊with @lucarlimite @beamusumeci1 @c_eike @v_puntmann academic.oup.com/ehjcimaging/ad… Myocardial edema largely represented, correlations with interstitial expansion, ECG changes and systolic function. Some considerations below 🧵

😊 first-authorship on @JACCjournals❗️ @beamusumeci1 jacc.org/doi/abs/10.101… - Thankful to @FraSantoroMD, Prof. ND Brunetti, @IngoEitel @t_stiermaier and @ibnsky for this collaboration and for setting up the #GEIST registry on its very beginning - few considerations below 🧵 1/8 Males represent approx. 10% of #Takotsubo patients within the registry. As comapred with females, they have ⬆️comorbid burden (malignancies, COPD etc.), ⬆️physical trigger ⬇️LVEF, worse in-hospital and long-term outcome.

1/ Case of te day, classic #HCM @beamusumeci1 @TiniGiacomo @domitillarusso 2/ Bright area in the LV septum/anteriore wall, seen already from trufi scout ... #WhyCMR

No, non è un bene scaricare le responsabilità sulla magistratura (thread) 🧵
@corzunino @PrecariUnitINFN @IoNonFaccioNien @MC_Carro

https://twitter.com/ramella_sociol/status/1491316323540160514

1/ Premessa - “Nell’università italiana il reclutamento segue nei fatti logiche slegate dai regolamenti concorsuali ”
Senza polemiche e moralismi, se si nega questo stato dell’arte, si può interrompere qua la lettura

Finally published on @journalofCMR!!! Cardiac biomarkers and #WhyCMR T1 and T2 mapping in people with chronic kidney disease - Thanks to @GoetheCVI @v_puntmann @c_eike jcmr-online.biomedcentral.com/articles/10.11… Few considerations below. We found independent associations between increasing natriuretic peptide/hsTropT on one side and myocardial involvement as assessed by native T1 and T2 mapping on the other ➡️ cardiac biomarkers=cardiac involvement (not only reduced elimination). (1/3)

Just published our latest work.

Investigating myocardial involvement in #COVID19 by troponin and BNP: dual center study on the first wave in Lazio region, Italy. link.springer.com/article/10.100… @mikeolangel @beamusumeci1 @P_Martelletti. Here it follows some considerations. 1. Increase of troponin/BNP was common in our sample, higher in patients with worse in-hospital prognosis (consistently shown in literature). Take into account epidemiological characteristics of the population: older age, high rate of comorbidity and fatal outcome.

Just published on @SciReports: disq.us/t/3qzu3fo,
Role of dyspnea at presentation in #Takotsubo. Thanks to
@FraSantoroMD @beamusumeci1 @lucarlimite @IngoEitel. Here it follows some considerations. 1- Dyspnea was associated with both worse in-hospital and long-term outcome. Similarly described in AMI (ref #12 and #13) in which heart failure symptoms at presentation might reflect wider myocardial damage. Why is it so even for a “transient” condition such as #Takotsubo?