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Patrick R. Secor Profile picture
Patrick R. Secor
@PRSecor
Associate Professor at U Montana. Studying bacteria and their viruses.
May 24, 2019 • 6 tweets • 3 min read
Filamentous phages spontaneously align and form liquid crystalline droplets when mixed with non-adsorbing polymers like hyaluronan

sciencedirect.com/science/articl… In addition to hyaluronan, filamentous phages form liquid crystals in DNA, mucin, glycosaminoglycans, and many more polymers. Shown here are Pf phage (green) mixed with human serum.
Mar 28, 2019 • 4 tweets • 2 min read
When I say #phage, do you think bacterial parasite? Superbug slayer (👀 @chngin_the_wrld)? #PhageTherapy?

Just out in @sciencemagazine, @bollyky and I find phage PROMOTE bacterial infection by directly triggering a maladaptive anti-viral immune response.

science.sciencemag.org/content/363/64… ABSTRACT: Pseudomonas aeruginosa (Pa) is a multidrug-resistant Gram-negative bacterium commonly found in health care settings. Pa infections frequently result in considerable morbidity and mortality.