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Ryan KC Yuen Profile picture
Ryan KC Yuen
@RKCYuen
Senior Scientist, Associate Professor (@SickKidsNews, @UofT) | Focuses on understanding the genetic architectures of complex disorders | Views are my own
Jul 27, 2020 • 9 tweets • 6 min read
Our new study is now out in @nature! We identified repeat expansions as a substantial genetic contributor to #autism, in collaboration with 38 researchers across @SickKidsNews, @UofT, @illumina, @verilylifesci, @autismspeaks & more ⤵️ (1/9)

Link: nature.com/articles/s4158… Thanks to advances in #genome sequencing, there have been improvements in clinical diagnosis & gene discovery for a variety of human disorders. Despite this, the number of genetic factors identified so far contribute less risk than expected - aka "missing heritability" (2/9)