A short thread on Group A Strep (GAS), invasive GAS (iGAS), scarlet fever and other conditions.
@UKHSA has released an epi report highlighting what we are detecting through notifications and reports from labs and clinicians gov.uk/government/pub… 1/8 Key points:
1. iGAS and Scarlet fever Season is earlier than pre-pandemic and higher levels have been seen throughout this year than during the pandemic
2. Rates of infection are 2-3 times higher than seen pre-pandemic at the same time of year
2/8

UKHSA guidance - In health and care settings, non-pharmaceutical interventions (such as mask wearing and enhanced ventilation) may be used, depending on local prevalence and risk assessment, with the aim to reduce the spread of SARS-CoV-2.
gov.uk/guidance/covid… UKHSA guidance for the public

gov.uk/guidance/livin…

🎈🎈Happy Birthday #SIRENStudy - the study opened 2 years ago & recruited ~45,000 healthcare workers for follow- up to study the impact of #COVID19 prior infection on re-infection; it then was modified to discuss the impact of #vaccination and #variants

ukhsa.blog.gov.uk/2022/06/20/the… Highlighting key papers
SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN)
The Lancet 397 (10283), 1459-1469
ncbi.nlm.nih.gov/pmc/articles/P…

monkeypox - a short thread.
Firstly a huge thank you to the people coming forward with symptoms, clinicians that are taking samples and helping us find cases, health advisors and health protection teams for tracing contacts, vaccination teams and inpatient management teams 👏 I want to add an additional thanks to organisations supporting us getting the message out in the best way possible @BASHH_UK @BritishHIVAssoc @THTorguk @Grindr and all other professionals who are working on Twitter and through their social contacts.

I lead the #SIRENStudy and have been studying the impact of prior infection with COVID-19 and COVID-19 vaccinations on immunity for more than 18 months. We have published multiple studies with collaborators. The most recent preprint is available here medrxiv.org/content/10.110… 1/6 In this pre-print, which is under peer review, we demonstrate that 2 doses of vaccination on top of prior of infection, significantly reduces both asymptomatic & symptomatic infection compared to infection alone - Table 3 - the longer since primary infection the more effect 2/6