Stefanie Grosswendt Profile picture
single-cell scientist, Independent Group Leader @berlinnovation/@ChariteBerlin/@BIMSB_MDC, From Cell States to Function in Embryos & Cancer
Aug 3, 2020 13 tweets 9 min read
We’re excited to share our newest publication @nature. With #scRNAseq we investigated 10 key #epigenetic regulators in #embryogenesis. Interesting early task for #Polycomb! Meissner lab @MPI_MolGen & @HSCRB /w @helenekretzmer & Zachary D. Smith (1/13) nature.com/articles/s4158… What is normal in #devbio? First, we generated a single-cell reference of WT mouse #gastrulation and early organogenesis to which we later compared mutant phenotypes. We identified 42 embryonic and extraembryonic cell states and placed them in a lineage tree. (2/13) Image