1/ Small Gupta family case series. Now 31 relatives + 4 friends with COVID in India. 32/35 took steroids. All were normoxic when given steroids (3 later deteriorated and actually needed them). 2/ Typical outpatient starting dose is medrol 32mg/day or equivalent. All of them get a taper, total duration 14-18 days. (If actually hypoxemic and hospitalized, doses are much higher - in the medrol 80 bid range. And durations even longer).

1/People keep asking what they can “do” now that they’re vaccinated (half of adults in Canada!). Can we follow the @CDCgov advice here in Canada too? What evidence can we use to guide us? 2/The @CDCgov has said that fully vaccinated people can attend small outdoor gatherings and even outdoor dinners without a mask, including with people who are unvaccinated.

1/Re. NACI’s recent communications. No one is saying to hide info from the public. What people are concerned about is the way that info is being conveyed (and to some extent, its accuracy). IMO, here is how they should have framed this: 2/First: all vaccines are extremely effective. All of them, including the AZ vaccine, will prevent severe disease and death in close to 100% of people. This is NOT about effectiveness.

1/Lots of discussions about #lockdown vs no lockdown in medicine, politics, around dinner tables, just about everywhere. @fordnation says he needs more evidence. I just reviewed the topic for a debate @accpchest. So I'll oblige. theglobeandmail.com/canada/article… 2/I'll start by stating the obvious: lockdowns work. This was shown in multiple Spanish Flu pandemic studies, including this one demonstrating reduced excess flu mortality with earlier, more aggressive lockdown, comparing 43 US cities: pubmed.ncbi.nlm.nih.gov/17684187/