Sourbha Satish Dani, MD, MSc, FACC, FASE Profile picture
Premature CAD Cardiologist, Outcomes research, Health Economics, Associate Prof @TuftsUniversity @UmassChan @LSEHealthpolicy PD @LaheyCardiology @HealthSustain
Apr 23 20 tweets 4 min read
The Hook
Cardiology trials keep telling you "20% risk reduction."
But what if that same trial meant:
→ 1 in 50 patients helped (NNT 50)
→ 49 of 50 got zero benefit
Welcome to the greatest trick in clinical trials: Relative Risk vs. Absolute Risk. A thread 🧵👇 Here's the difference in 30 seconds:
RELATIVE RISK REDUCTION (RRR): % decrease vs. control → "Risk was cut BY 50%."
ABSOLUTE RISK REDUCTION (ARR): Actual percentage point difference → "Risk went from 2% → 1%."
Same trial. Two very different stories.
Mar 17, 2023 8 tweets 10 min read
Heartiest Congratulations on #Match2023 #MatchDay2023 #MatchDay
Take a moment to cherish the fruits of your hard work and perseverance! Let's not lose hope if you did not match #IMGs #AMGs! Failure is an opportunity to learn, a process to achieve your dream! @TheNRMP @ECFMG_IMG The application pool is strong! So, Do Not Give up! Let's celebrate success and learning! Cheers! Know that the universe wants you to do well! A loving family, friends, well-wishers, teachers, mentors want you to succeed!