Amir, PharmD Profile picture
I talk about drugs, diseases, drugs, misinformation, and drugs. Opinions mine and not particularly good.
Dec 28, 2022 7 tweets 2 min read
This is your periodic, completely random recommendation to not let a chiropractor touch your neck. Bonus comment: (Actual) medicine is a balance of risks and benefits.

If your intervention has no proven benefits, then any risk is unacceptable.
Mar 5, 2022 5 tweets 4 min read
⭐ Transplant immune suppression failure from St John's Wart

⭐ Kidney stones from high dose vitamin C

⭐ Blunted response to platinum-based chemo due to antioxidant supplement

⭐️ Hypercalcemia and falls from high dose Vit D ⭐ Diarrhea from magnesium supplements

⭐ Chronic insomnia from a supplement secretly containing banned stimulants

⭐ Liver failure requiring transplant from a contaminated herbal product

⭐ Antibiotic AND thyroid supplement failure from crazy iron use
May 17, 2021 16 tweets 7 min read
1/ Forget COVID for a sec! Come read about 🌟𝘱𝘭𝘢𝘤𝘦𝘣𝘰𝘴🌟 instead.

Is placebo effect as powerful as some suggest?
Not really.
But it's surprisingly consistent, & that has important implications in medicine.

I dug up an old student presentation on them.
Let’s dive in🧵 Quote from Emile Coue "... 2/ The term was 1st used in medicine in the 1800s: Treatment "adapted more to please than to benefit".

Even then, the importance of suggestion/placebos/bedside manner/whatever you call it was known to be tremendously important.
Apr 5, 2021 10 tweets 4 min read
1/ The message is consistent: Variants are causing more severe infection in younger people.

You’ve seen the stories of 30-40 year olds in the ICU, on heart/lung machines, and dying.

So from a rehab hospital, let me tell you about some of the survivors. 🧵 2/ We see #COVID19 survivors of all ages. Early 30s to late 90s.
- Severe cases often have some lung injury.
- Many develop heart issues or have existing ones worsen.
- Going from “frequent hikes” to “need to catch my breath halfway up a flight of stairs” is a common complaint.
Feb 14, 2021 23 tweets 8 min read
1/ Plenty of people like @deonandan and @DeNovo_Fatima have made great points on the #VitD buzz. Here's my 2 cents.

Title:
𝑊ℎ𝑦 𝑎𝑟𝑒 𝑚𝑜𝑠𝑡 𝑠𝑐𝑖𝑒𝑛𝑡𝑖𝑠𝑡𝑠/𝑑𝑜𝑐𝑡𝑜𝑟𝑠 𝑠𝑢𝑐ℎ 𝑏𝑢𝑧𝑧𝑘𝑖𝑙𝑙𝑠 𝑎𝑏𝑜𝑢𝑡 𝑉𝑖𝑡 𝐷 𝑟𝑖𝑔ℎ𝑡 𝑛𝑜𝑤?

Man I suck at titles.
🧵 2/ Let's start with 2 summaries. All sources at the end.

𝗧𝗟;𝗗𝗥 #𝟭 - For most people, it's safe to take anywhere from 200 to 4000iu of Vit D/day.

We just don't want ppl to think these pills are an alternative to social distancing,😷, or medical help if you're sick. E.g. ⬇️
Jan 1, 2021 8 tweets 5 min read
When pts ask me why I'm skeptical of #supplements by default, I give examples to highlight the lack of regulation+data. I wrote some here.

Title: “Some reasons I'm cautious with supplements and would rather you get the nutrients in your diet"

Rolls off the tongue, I know.🧵 1) The largest trials of antioxidant 💊showed they don’t ⬇️risk of cardiovasc events, diabetes, cancer, or cognitive decline.
Some showed ⬆️hemorrhagic stroke and prostate cancer, but it’s inconsistent.

pubmed.ncbi.nlm.nih.gov/17698683/

pubmed.ncbi.nlm.nih.gov/19066368/

ncbi.nlm.nih.gov/pmc/articles/P…